tetano
Editor, Senior Moderator
Infect Chemother
. 2020 Jun 12.
Online ahead of print.
Age Related Morbidity and Mortality Among Patients With COVID-19
Seung Ji Kang[SUP] 1 [/SUP], Sook In Jung[SUP] 2 [/SUP]
Affiliations
Abstract
On March 11, 2020, the World Health Organization declared coronavirus disease (COVID-19), caused by the novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a pandemic. During the COVID-19 pandemic, an age-associated vulnerability in the burden of disease has been uncovered. Understanding the spectrum of illness and the pathogenic mechanism of the disease in a vulnerable population is critical, especially during the pandemic. Herein, we reviewed published COVID-19 epidemiology data from several countries to identify any consistent trends in the relationship between age and COVID-19-associated morbidity or mortality. We also reviewed the literature for studies explaining the difference in the host response to SARS-CoV-2 infection according to age. The insights from these data will be useful in determining the treatment policies and preventive measures of COVID-19.
Keywords: Age; COVID-19; Morbidity; Mortality; Pandemic.
. 2020 Jun 12.
Online ahead of print.
Age Related Morbidity and Mortality Among Patients With COVID-19
Seung Ji Kang[SUP] 1 [/SUP], Sook In Jung[SUP] 2 [/SUP]
Affiliations
- PMID: 32537961
Abstract
On March 11, 2020, the World Health Organization declared coronavirus disease (COVID-19), caused by the novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a pandemic. During the COVID-19 pandemic, an age-associated vulnerability in the burden of disease has been uncovered. Understanding the spectrum of illness and the pathogenic mechanism of the disease in a vulnerable population is critical, especially during the pandemic. Herein, we reviewed published COVID-19 epidemiology data from several countries to identify any consistent trends in the relationship between age and COVID-19-associated morbidity or mortality. We also reviewed the literature for studies explaining the difference in the host response to SARS-CoV-2 infection according to age. The insights from these data will be useful in determining the treatment policies and preventive measures of COVID-19.
Keywords: Age; COVID-19; Morbidity; Mortality; Pandemic.