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The POTENTIAL IMMUNOGLOBULIN Y (IgY) AS THERAPY IMMUNITY PASSIVE TO THE PATIENT FLU BURUNG
Juli 1, 2008
Akbar Fahmi, Akbar Satrianegara
The Airlangga University school of medicine, Surabaya, 2008
ABSTRAK
Bird flu spread from South-East Asia to Asian Tengah, Africa and Europe.
Met by the existence of the case of the spread to humankind that often caused the death (Hien et al, 2004).
This illness was caused by the virus that was mentioned H5N1.
Since May 2005, the number of endemic countries and cases that was confirmed (340 cases on December 14 2007) increased, one of his causes was the spreading clade 2,2 went through Europe, Asia and Africa.
The vaccination offered the opportunity that was good for prevented the illness and reduced the death rate in one pandemik, but had the limitations in punctuality and the availability of the vaccine (Stohr and Esveld, 2004).
Technology IgY offered the other solution that often still not glance at by ilmuan.
IgY was protein that functioned as antibodies to the chicken and the poultry.
The hen transferred immunity to his descendants melaui the egg yolk (Klemperer, 1893).
The chicken kept the content IgY that was high to the egg yolk and was the producer of efficient antibodies (Gottstein and Hemmeler, 1985).
In time 6 weeks, one chicken that already terimunisasi produced 298 g IgY, higher than the antibodies serum (16,6 mg) that was taken from one rabbit (Nakai et al, 1994).
Moreover, was based on the distance filogenetik between the poultry and the mammal (Jensenius et al, 1981), the chicken produced more specific antigens to oppose mammalian antigens than that could the mammal did.
For example, BSA (Ermeling et al, 1992) and serum human (Lo?sch et al, 1986), more antigenik against the species of the poultry daipada the mammal. IgY more superior against serum antibodies that were caused by the height of the level of specific antibodies (Orlans, 1967; Rose et al, 1974) and the relative reduction from purification (Akita and Nakai, 1992) with the level of the low loss (Polson and Von Wechmar, 1980). Antibodies to the egg yolk also had the benefit more than serum antibodies because kompabilitas him towards the modern protection rule. (Gottstein and Hemmeler, 1985).
Therapy IgY as passive in the defence system of humankind could be proposed was given to the person who was infected by the virus H5N1 as efforts to give passive immunity to the patient so as to be able to increase the life expectancy.
Giving of therapy better per oral so as more effective gave immunity towards the virus H5N1 theoretically.
http://forismafkunair.wordpress.com...terapi-imunitas-pasif-pada-pasien-flu-burung/
Juli 1, 2008
Akbar Fahmi, Akbar Satrianegara
The Airlangga University school of medicine, Surabaya, 2008
ABSTRAK
Bird flu spread from South-East Asia to Asian Tengah, Africa and Europe.
Met by the existence of the case of the spread to humankind that often caused the death (Hien et al, 2004).
This illness was caused by the virus that was mentioned H5N1.
Since May 2005, the number of endemic countries and cases that was confirmed (340 cases on December 14 2007) increased, one of his causes was the spreading clade 2,2 went through Europe, Asia and Africa.
The vaccination offered the opportunity that was good for prevented the illness and reduced the death rate in one pandemik, but had the limitations in punctuality and the availability of the vaccine (Stohr and Esveld, 2004).
Technology IgY offered the other solution that often still not glance at by ilmuan.
IgY was protein that functioned as antibodies to the chicken and the poultry.
The hen transferred immunity to his descendants melaui the egg yolk (Klemperer, 1893).
The chicken kept the content IgY that was high to the egg yolk and was the producer of efficient antibodies (Gottstein and Hemmeler, 1985).
In time 6 weeks, one chicken that already terimunisasi produced 298 g IgY, higher than the antibodies serum (16,6 mg) that was taken from one rabbit (Nakai et al, 1994).
Moreover, was based on the distance filogenetik between the poultry and the mammal (Jensenius et al, 1981), the chicken produced more specific antigens to oppose mammalian antigens than that could the mammal did.
For example, BSA (Ermeling et al, 1992) and serum human (Lo?sch et al, 1986), more antigenik against the species of the poultry daipada the mammal. IgY more superior against serum antibodies that were caused by the height of the level of specific antibodies (Orlans, 1967; Rose et al, 1974) and the relative reduction from purification (Akita and Nakai, 1992) with the level of the low loss (Polson and Von Wechmar, 1980). Antibodies to the egg yolk also had the benefit more than serum antibodies because kompabilitas him towards the modern protection rule. (Gottstein and Hemmeler, 1985).
Therapy IgY as passive in the defence system of humankind could be proposed was given to the person who was infected by the virus H5N1 as efforts to give passive immunity to the patient so as to be able to increase the life expectancy.
Giving of therapy better per oral so as more effective gave immunity towards the virus H5N1 theoretically.
http://forismafkunair.wordpress.com...terapi-imunitas-pasif-pada-pasien-flu-burung/
