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Indonesia: The Clinical sign of Bird Flu Increasingly was difficult to be recognised

Commonground

Senior Moderator
Indonesia: The Clinical sign of Bird Flu Increasingly was difficult to be recognised

[There are 2 other articles from back in July, on this strain in Purwakarta]

MINGGU, 11 JANUARI 2009 | 17:40 WIB

Jakarta, on Sunday ? the bird flu diagnosis to the poultry increasingly was difficult to be carried out because his clinical sign resembled several other endemic illnesses. So, the breeders and the community must generally increase his vigilance because the poultry that was infected by this bird flu continued to be able to become the source of the spread to humankind. According to the Dean of the School Of Veterinary Medicine of Institut Pertanian Bogor (IPB) I Wayan Teguh Wibawan, on Sunday (11/ 1), when being contacted from Jakarta, the nonexistence of the clinical sign that was typical to the poultry that was infected by bird flu showed the illness was endemic. "This happened not only to the nonpedigreed chicken, but also to the thoroughbred chicken," he said.

"However, that not meant to the change" in the "characteristics" of the "virus happen." Because results of the research showed the virus to the poultry that was given the vaccine stayed cruel, there was this possibility of happening because of the bird flu virus that attacked not 100 percent agreed with antibodies to the chicken, including antibodies that was formed by the vaccine, said Wibawan added. For example, till at this time the group of the bird flu virus from Purwakarta and Sukabumi was different from all the available vaccines in Indonesia. [*See 2 Posts Below this article] That because antigenisitas this virus group was different from two other virus groups in Indonesia, that is the classic Legok group and the South Sulawesi virus group. The manifestation of the illness was sub-clinical showed, it was warned bird flu viruses could be detected and isolated from chickens that appeared healthy. The chicken that was seen healthy then could contain the bird flu virus. "That must be paid attention to because his virus was raging and could be the source" of the "spread," said Wibawan

"Therefore, the bird flu vaccination necessarily only as accessories from the bird flu precaution to the poultry." That more must be paid attention to was sanitation or biosecurity, among them the official must bathe with soap as well as changed clothes and sandals before entering the pen, the handling a camp as the pen foundation, he said.


*Article from April 30th, 2008]

The Immune virus the Vaccine was found
Rabu, 30/04/2008

The Directorate General (the Director General) Departemen Livestock Breeding of Agriculture found the existence of the virus of H5N1 strain Purwakarta (PWT) immune the bird flu vaccine.

His article, the poultry in Indonesia has experienced mutation. Now, this virus has spread in Purwakarta, some Subang, some of Jakarta, and Tangerang.
Director Kesehatan of the Dirjen Animal of Deptan Livestock Breeding, Musny Suatmodjo, worried the occurrence of the jump of the case of bird flu to the poultry that was difficult to be combatted if strain that mutated with the other flu virus.
According to Musny, since 2003 till 2006, this virus experienced antigenic drift, so as not vulnerable if vaccinated by using the normal poultry vaccination.
"From 2003 to 2006, this virus experienced antigenic drift, around 27% his amino acid changed so as not vulnerable if vaccinated by using the normal poultry vaccination was used in Indonesia," said Musny to the reporter ended to the speaker in "Insentifikasi Controlling discussions of Bird Flu" that was spread out by the Service of Peternakan West Java yesterday afternoon.
Musny said, uptil now the poultry vaccination that was given to press the spreading of the bird flu virus was the vaccine kind H5N1, H5N2, and H5N9.
Outside strain PWT, said Musny, his side guaranteed the vaccination that circulated to protect the poultry from the bird flu attack was still effective was used for three strain big H5N1 other that is Papua, Sukabumi, and Bali.


With the discovery of the virus of this H5N1 PWT, Musny ordered so that the Service of Peternakan West Java did bio security tightly for all poultry livestock breeding in the region that had strain PWT. Diperkirakan, said he, the number of poultry populations in the region that had strain PWT reached 50 million tails and most were maintained in big livestock breedings.
"Bio security against the poultry at this time must be tighter so that always disinfektan from equipment, vehicle food and his humankind.
His humankind also if entering the location of the pen must with bathed and shampoo hair.

Next month we will also test all strain certain and from the expert's commission broke that would we the test with strain from Sukabumi, X said Musny.
He added, for the program of the poultry vaccination in Indonesia during 2008, has been prepared by 175 million doses of the vaccine H5N1.
65 million doses including being the contribution from the World Bank.
This number, said Musny, still a little compared with the number of targets of the poultry vaccination in sector four in the high risk territory that reached approximately 200 million from around 400 million poultries in sector four.
In the meantime, Peternakan West Java Rachmat Setiadi Section Head said, at this time the step bio security and surveillance continued to be carried out to prevent infected him bird flu in West Java, especially in the territory strain PWT.

Moreover, continued Rachmat, communication with the big breeders also continued to be carried out so that they are careful because of the vaccine that circulated in Indonesia evidently not vulnerable.
On the other hand, the application of the governor's regulation (pergub) no 19/2007 about the Control of Bird Flu apparently was not yet it was considered important by the regent and the guardian of the city.
[Link does not function anymore]

[Another article on the same subject, from July 2, 2008]
The Bird Flu groove was Just found in Purwakarta

The Penelitian Veteriner hall (Balitvet) Bogor, West Java, found the groove (strain) the new bird flu virus in Purwakarta.
Peternakan West Java Rachmat Setiadi Section Head said, in accordance with his location, the groove that was suspected of by results of the mutation being acknowledged also as the Purwakarta groove with the specific code strain PWK.
Director Kesehatan of the Animal Directorate General Peternakan Departemen of Musny Suatmodjo Agriculture said, strain that was the bird flu virus that had emerged in this territory in 1976.
"Strainnya continue to H5N1, only available protein compositions inside were different," he said when being contacted the Time, yesterday.

The difference of the protein composition caused the bird flu vaccine that uptil now was used in Indonesia to become ineffective.
Despite this, Musny guaranteed the bird flu virus of H5N1 strain Purwakarta not turn off like strain other bird flu.
The difference that was specific in the protein composition in strain Purwakarta, according to Musny, happened resulting from the mutation in the virus body personally.
However the mutation did not change the composition like perubahan [a change; alteration; mutation; transformation; transmutation; transition; adjustment; switch; conversion]
the form from H5N1 became the kind H5N2.
To map the explanation of the bird flu virus, according to Rachmat, Dinas Peternakan spread out the co-operation with Balitvet.
"Kami was discussing that with Balitvet," he said.
Apart from in Purwakarta, strain same was reported emerged in several other territories.
Strain just like that, Musny continued, also to be found in the Sukabumi territory, Subang and Jakarta.
"Penyebarannya only in the area," he said.
[link does not function anymore]​
 
Re: Indonesia: The Clinical sign of Bird Flu Increasingly was difficult to be recognised

Source: http://www.kompas.com/read/xml/2009/01/13/08053829/AI.Tak.Terdeteksi

Google translation:
AI Not Detected
Clinical symptoms of Bird Flu No More Specific

Tuesday, 13 January 2009 | 08:05 WIB
JAKARTA, KOMPAS - bird flu virus mutation memapar the poultry in Indonesia since 2003 has caused a new problem. Poultry fell ill that bird flu virus is now no longer show clinical symptoms of the more specific so difficult recognized.

Likewise opinion poultry disease experts from Gadjah Mada University, who is also member of the panel of experts Control Committee of the National Bird Flu and pandemic influenza Facing Preparedness (Komnas FBPI), Charles Rangga Tabbu, when contacted last week in Yogyakarta.

According to him, the problem of avian influenza (AI) in the new Indonesia is a virus that attacks the birds now klinisnya symptoms vary with the year 2003. Similarly, damage to the poultry network.

"We have difficulties diagnose bird flu in poultry in the field. Formerly the birds fell ill easily recognizable, but not now,
"said Charles who is also Chairman of the Association of Veterinarians poultry Indonesia. Subklinis difficult to guess the form of the symptoms and not specific.

According to him, the clinical symptoms that can not be observed with the naked eye or hold the fuselage. "It should be done in the lab examination," said the lecturer at the Faculty of Veterinary Medicine pathology UGM this.

It disclosed senada Dean of Faculty of Veterinary Medicine Bogor Agriculture Institute (IPB) I Wayan Teguh Wibawan, Sunday (11 / 1). "Clinical symptoms and patologis bird flu in poultry, especially chickens, the more difficult because diagnosed very varied, both the chicken and the race is not race," he said.

According to him, the clinical symptoms, such as purple on the crest, foot, leg and kebiruan, not necessarily appear. "Moreover, the death of poultry bird flu is not high, can be distracted identification. Residents confused, it tetelo or bird flu, "he said.

Changes in symptoms of this mutation caused the virus or because the birds have been vaccinated ago contact with the virus. Antibody that is not too strong the virus remains lodged in the birds themselves and leaving the virus in the feces (viral shedding).

"Always have to have a laboratory to help detect the virus or virus isolation to do with technology or amplification genes or viruses," she explains.


Now signs of clinical bleeding or live-The speck The speck on the red body organs including chicken intestine and kidney. The problem is, bleeding in the body's organs are also found on a chicken disease Ende, cholera, and gumoro.

"This is art with a diagnosis epidemiologis, patologis, history to sick poultry, the vaccine is given, the examination and PCR," he said.

Similarity in nature

According to Charles, so that effective vaccination should seek similarity nature biological and genetic composition of the same. Furrow subtipe virus vaccine and the vaccine must homolog with the field virus.


For example, to this group of AI virus from Sukabumi and Purwakarta different with all the vaccines in Indonesia. That's because this virus antigenisitas group with two different groups of the virus in Indonesia, namely the classic virus Legok and South Sulawesi.

Director of Animal Health Ministry of Agriculture, Ad Interim Turni Rusli, said the virus mutation may occur. Therefore, as anticipated, the government efforts to make early detection, among others, with the community to react quickly on a variety of historical information or new information concerning the case of AI.

"If there is information in a village, the direct approach, to the destruction and targeted vaccination," he said.

In addition to have antibody, birds also have cellular immunity in the show clinical signs of disease. However, that does not mean the virus mutation occurs.

"It's possible this happened because the bird flu virus which attacked not 100 percent fit with the antibody on the chicken, including the antibody made by the vaccine," said Wibawan.

Manifestation of the disease are subklinis show, that the virus, bird flu virus can be detected and diisolasi of chicken-chicken that looks healthy. "Note virusnya as violent," he said.

About the symptoms, Health Minister Siti Fadilah Supari said the bird flu in poultry should continue to be encouraged by the Ministry of Agriculture.

According to Menkes, meet the press after a matter of the program plan MOH in 2009, yesterday, also complete the MOH facilities 100 hospitals bird flu, along with two national reference laboratory bird flu National Research and Development of Health and Eijkman Institute, 8 laboratory regional, subregional and 34 laboratory .

In addition, the MOH distributing oseltamivir to health agencies, hospitals reference bird flu, public hospital districts / cities, private hospitals that treat cases of bird flu, and health centers in all provinces in Indonesia. (MAS / Evy)
 
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