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Indonesia increases risk by failing to share bird flu samples: WHO

HenryN

Retired
Indonesia increases risk by failing to share bird flu samples: WHO <!-- END HEADLINE -->
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Indonesia, the country hardest hit by human cases of bird flu this year, is putting the world at risk by failing to share samples of the virus, a senior international health official said Monday.
The sharing of laboratory samples from H5N1 bird flu victims is essential to keep track of any mutations in the virus that might herald the development of an even deadlier pandemic strain of influenza, according to the World Health Organisation.
"The one country that has not yet shared viruses with us this year is Indonesia," David Heymann, WHO assistant director general for communicable diseases, said in a conference call with journalists.
Heymann said that by not sharing samples with WHO research laboratories, Indonesia was putting its own population in danger because anti-flu vaccines developed by industry would not contain components of Indonesian bird flu infections.
"The second thing Indonesia is doing is putting the public health security of the whole world at risk because they're not sharing viruses," he added.
Indonesia had stopped sharing virus samples with foreign laboratories in December 2006 because it feared multinational drug companies could use them to develop vaccines that were not affordable for poor countries.
It is seeking changes to the global flu surveillance system to ensure developing countries get a fair deal.
Negotiations are under way to reach an agreement on detailed international virus sharing guidelines at a special meeting of the WHO's member states in November.
Tensions over the issue had seemingly eased in May after talks on virus sharing began, and Indonesia said it had resumed sending H5N1 specimens to a WHO laboratory in Tokyo.
However, Heymann revealed Monday that the three specimens Indonesia sent to Tokyo did not have live flu viruses in them, and two were from the same person.
Twenty-seven of the 56 human cases of H5N1 bird flu recorded by the WHO this year have occurred in Indonesia. It also has by far the highest death rate, accounting for 23 out of the 34 deaths recorded in six countries this year.
China had shared samples of viruses with the WHO's international network of laboratories in June, Heymann said.
Meanwhile, Vietnam has been trying to send samples, but the shipment has not been cleared yet because of problems with ensuring the consignment complies with strict biosafety rules, he added.


http://news.yahoo.com/s/afp/2007080...a&printer=1;_ylt=AsZxrdMQtM2RNZ.U7TYk3TiKOrgF
 
Re: Indonesia increases risk by failing to share bird flu samples: WHO

now, what is with these samples which Indonesia sent to Tokyo,
will they be sequenced and published ?
And if yes, when ?
And, shouldn't we repeat the last year's petition,
which may have contributed that Indonesia
started sharing samples in July 2006 ?

Why is it so silent now about OFFLU and GISAID ?

If the _real_ concern of Indonesia is the vaccine,
then why don't they share the inner genes at least
or the 3rd postitions ?
 
Re: Indonesia increases risk by failing to share bird flu samples: WHO

now, what is with these samples which Indonesia sent to Tokyo,
will they be sequenced and published ?
And if yes, when ?
And, shouldn't we repeat the last year's petition,
which may have contributed that Indonesia
started sharing samples in July 2006 ?

Why is it so silent now about OFFLU and GISAID ?

If the _real_ concern of Indonesia is the vaccine,
then why don't they share the inner genes at least
or the 3rd postitions ?
Please, the issue in Indonesia is VERY different than individuals hoarding sequences.
 
Re: Indonesia increases risk by failing to share bird flu samples: WHO

Indonesia yet to share live H5N1 virus samples: WHO
06 Aug 2007 16:04:21 GMT
<!-- 06 Aug 2007 16:04:21 GMT ## for search indexer, do not remove-->Source: Reuters

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<!-- AN5.0: inline article box end --><SCRIPT language=JavaScript src="/bin/js/article.js"></SCRIPT> By Laura MacInnis
GENEVA, Aug 6 (Reuters) - Indonesia has yet to provide usable samples of the H5N1 bird flu virus to the World Health Organisation, compromising international efforts to prepare for a pandemic, a top WHO official said on Monday.
David Heymann, assistant director-general for communicable diseases at the U.N. agency, said the three specimens Jakarta sent in May, which came from two humans infected with the deadly influenza strain, contained fragments but no live virus.
Indonesia is now the only country that has not shared samples of H5N1 that drugmakers can use to develop vaccines. Heymann said this raised global pandemic risks, given that vaccines now being developed cannot protect against the virus mutations that proved lethal there.
"Indonesia is aware of these issues and is working with WHO ... to see how they can best begin sharing again," he said. "We are hoping that that will begin fairly soon."
Indonesia has had 81 confirmed human deaths from bird flu, more than any other country. The disease is endemic among birds in most parts of Indonesia, where millions of backyard chickens are kept close to humans.
Although most people who have caught bird flu have had direct or indirect contact with infected fowl, experts fear the constantly-mutating virus could change into a form easily transmitted from person to person and sweep the world.
Jakarta, which has complained poor nations would not be able to afford vaccines being developed, earlier this year refused to share virus samples with the WHO unless it had guarantees they would not be used commercially.
While it later agreed to ship specimens under a deal with the Geneva-based agency meant to improve access to vaccines, Heymann said Indonesia had not shared any virus samples since the three unusable ones were shipped in May.
China last sent bird flu samples in June. Vietnam has been trying to share specimens but is currently wrestling with shipping regulations, both in Vietnam and abroad, he said. H5N1 vaccines developed from live virus samples could be used to contain an early epidemic among humans or could be used to prime certain populations for a possible outbreak to give them a certain amount of immunity, Heymann said.
Influenza vaccines have to be reformulated every year to match the circulating strains because the virus mutates often.
Health experts met in Singapore last week to discuss how influenza viruses should be shared, a debate that is expected to continue until the World Health Assembly in May 2008 when the WHO's 193 member states formally take up the issue.
According to WHO figures, 319 people have become infected with bird flu since 2003 and 192 have died.

http://www.alertnet.org/thenews/newsdesk/L63164.htm
 
Re: Indonesia increases risk by failing to share bird flu samples: WHO

<TABLE style="DIRECTION: ltr" width="100%" border=0><TBODY><TR><TD>WHO: Indonesia Not Sharing Bird Flu Virus Samples</TD></TR><TR><TD vAlign=top>By Lisa Schlein
Geneva
06 August 2007
</TD><TD vAlign=top align=left></TD></TR></TBODY></TABLE>Schlein report (mp3) Download 693k
audio_icon.gif

Listen to Schlein report (mp3) Download 693k


The World Health Organization says all countries, with the exception of Indonesia, are sharing their avian influenza viruses. WHO says the failure to share virus samples could retard the development of an effective bird flu vaccine and could increase the dangers of a potential pandemic. Lisa Schlein reports for VOA from Geneva.
<TABLE class=APIMAGE style="DIRECTION: ltr" width=210 align=left><TBODY><TR><TD>
ap_switzerland_who_david_heymann_195_23Oct06.jpg
</TD></TR><TR><TD class=imagecaption>David Heymann, WHO Assistant Director-General for Communicable Diseases (file photo)</TD></TR></TBODY></TABLE>The World Health Assembly passed a resolution requiring all countries to share their avian influenza viruses. WHO Assistant Director-General for Communicable Diseases, David Heymann, says countries that do not share viruses are not in compliance with that resolution.
He tells VOA it is important for governments to share viruses they isolate from humans because the virus mutates in an unpredictable manner.
"So, by not sharing viruses, Indonesia is actually harming two things," said Dr. Haymann. "It is putting in danger its own population because if those viruses are not freely shared with industry, vaccines will not contain the elements of the Indonesia infections."
"And, the second thing that Indonesia is doing is, therefore, putting the whole world at risk, the public health security of the world at risk because they are not sharing viruses," he added.
Dr. Heymann says the Indonesian government is aware of these issues. He says he is hopeful that Indonesia will fall in line, but there is no guarantee this will happen.
Indonesia suspended its voluntary transfer of avian flu virus samples to the World Health Organization early this year. It complained pharmaceutical companies in western countries were using its viruses to develop a vaccine and that developing countries would not benefit from this research.
Dr. Heymann says WHO is developing ways to make sure the benefits from a vaccine would be broadly shared. He says this has already begun. WHO has a stockpile of 50 million doses of available H5N1 vaccines, which would be distributed to countries in need.
He says WHO also is helping developing countries that want to produce their own vaccines.
"WHO has given grants to six countries in the world, six developing countries, after having received proposals from them to transfer technology using resources that have been provided by the United States, Japan and the Asian Development Bank and Canada," said Dr. Haymann.
"So, WHO is working to help transfer the technology. That would be a sustainable means of making sure that pandemic vaccines were available. And, then in addition developing a mechanism to be sure that vaccine could be obtained during a pandemic," he continued.
The countries that have requested help in developing their own bird flu vaccines are Brazil, Mexico, India, Indonesia, Thailand and Vietnam.
The World Health Organization reports 192 people have died from bird flu. Indonesia, with 81 reported deaths, is the most severely affected country.
So far, avian influenza is a largely animal disease. But, WHO warns millions of people could become infected if the H5N1 bird flu virus mutates into a form that could be easily spread from one human to another.

http://www.voanews.com/english/2007-08-06-voa54.cfm?renderforprint=1
 
Re: Indonesia increases risk by failing to share bird flu samples: WHO

can there be UNO-sanctions against Indonesia,
is it possible just in theory ?
 
Re: Indonesia increases risk by failing to share bird flu samples: WHO

can there be UNO-sanctions against Indonesia,
is it possible just in theory ?

This looks like a good place to start...
"So, WHO is working to help transfer the technology. That would be a sustainable means of making sure that pandemic vaccines were available. And, then in addition developing a mechanism to be sure that vaccine could be obtained during a pandemic," he continued.
The countries that have requested help in developing their own bird flu vaccines are Brazil, Mexico, India, Indonesia, Thailand and Vietnam.
Try as I might, I cannot understand this logic. Is this some sort of kamikaze game?

Indonesia had stopped sharing virus samples with foreign laboratories in December 2006 because it feared multinational drug companies could use them to develop vaccines that were not affordable for poor countries.
 
Re: Indonesia increases risk by failing to share bird flu samples: WHO

Indonesia had stopped sharing virus samples with foreign laboratories in December 2006 because it feared multinational drug companies could use them to develop vaccines that were not affordable for poor countries.

I fail to see how guaranteeing an appropriate vaccine is even available can improve the affordability.:confused:

In-country VAX capacity seems the ultimate solution for all countries.

.
 
Re: Indonesia increases risk by failing to share bird flu samples: WHO

that would imply that Indonesia considers not affordable
vaccines as worse than no vaccines at all.
Doesn't make sense. Just a formulation how they
hope to hide that it's just blackmail.
 
Re: Indonesia increases risk by failing to share bird flu samples: WHO

David Heymann, said the agency had received three specimens from Jakarta in May, but none contained any live virus.

Jakarta wanted assurances that any vaccines developed would not be too expensive for developing nations.

It ended its boycott in May, however, after receiving assurances from WHO that the virus samples would be used for risk assessment and not passed on to private pharmaceutical companies without Jakarta's permission.

http://www.thejakartapost.com/detailgeneral.asp?fileid=20070807161526&irec=0

the only samples it has sent, in May, were unusable

?He?s not a scientist, he should ask the scientists,? Dr Triono said. ?The samples have been sequenced and can be used for risk assessment and to assess whether there has been a mutation.?

http://www.ft.com/cms/s/63ed6b18-44b3-11dc-82f5-0000779fd2ac.html



so, did WHO receive Indonesian sequences in May,
but no live virus and but kept the sequences secret ?
And neither GISAID nor OFFLU nor niman nor Branswell
nor... said anything about it ? Or did I miss something ?
 
Re: Indonesia increases risk by failing to share bird flu samples: WHO

gsgs said:
so, did WHO receive Indonesian sequences in May,
but no live virus and but kept the sequences secret ?
And neither GISAID nor OFFLU nor niman nor Branswell
nor... said anything about it ?
Well, if it was a SECRET, how would these other people/organizations know about whether they were live viruses or not? ???
 
Re: Indonesia increases risk by failing to share bird flu samples: WHO

I mean, the exact nucleotides of the sequences are secret
not the existence of the sequences.

And secret maybe only to public, not to WHO.
It could be in the secret WHO database, although
they had announced earlier, they would give it to GISAID.
http://www.gisaid.org/pr_20070329_en.html

However the GISAID policy of making sequences public is still unclear
to me despite several email "explanations" from GISAID. No reply from OFFLU.
 
Re: Indonesia increases risk by failing to share bird flu samples: WHO

I mean, the exact nucleotides of the sequences are secret
not the existence of the sequences.

And secret maybe only to public, not to WHO.
It could be in the secret WHO database, although
they had announced earlier, they would give it to GISAID.

However the GISAID policy of making sequences public is still unclear
to me despite several email "explanations" from GISAID.
The CDC has MANY deposits in the WHO secret database, but they have published the human Indonesian sequences. Similarly, the WHO reference lab in Australia has published the Indonesian bird sequences, including samples from 2007, and they also submit to the WHO secret database.

Linking the WHO database (which is a problem for OTHER H5N1 sequences like those from Europe) to the Indonesian SEQUENCES really makes no sense and simply creates confusion (although such comments do also show who is confused).
 
Re: Indonesia increases risk by failing to share bird flu samples: WHO

and your comment didn't help to unconfuse.
Maybe someone else can reformulate ?


Did WHO receive human Indonesian Indluenza sequences in May ?
When will they be available ?
Why is niman no longer concerned about withheld Indonesian sequences ?
 
Re: Indonesia increases risk by failing to share bird flu samples: WHO

I mean, the exact nucleotides of the sequences are secret
not the existence of the sequences.

And secret maybe only to public, not to WHO.
It could be in the secret WHO database, although
they had announced earlier, they would give it to GISAID.
http://www.gisaid.org/pr_20070329_en.html

However the GISAID policy of making sequences public is still unclear
to me despite several email "explanations" from GISAID. No reply from OFFLU.
Well, I still ask then, if the exact nucleotides of the sequences were a SECRET, how would these other people/organizations know about them?

You aren't making any sense as far as I can see. :confused:
 
Last edited:
Re: Indonesia increases risk by failing to share bird flu samples: WHO

uhh, secret means, unavailable to public, only available to
the 15 or such WHO referrence labs.

Why is it unclear now ? We were talking about this problem since years.

Who has access to the Indo human sequences from May 2007 ?

When will they be available to me ?
 
Re: Indonesia increases risk by failing to share bird flu samples: WHO

uhh, secret means, unavailable to public, only available to the 15 or such WHO referrence labs.
Well, what I don't understand is how Helen Branswell or Dr. Niman enter into this? If the WHO kept this a SECRET, how on earth would they know?????
 
Re: Indonesia increases risk by failing to share bird flu samples: WHO

sorry, you lost me. My confusement ever increases...
 
Re: Indonesia increases risk by failing to share bird flu samples: WHO

Linking the WHO database (which is a problem for OTHER H5N1 sequences like those from Europe) to the Indonesian SEQUENCES really makes no sense and simply creates confusion (although such comments do also show who is confused).

I don't undestand why, doctor Niman
I don't understand the protocol of "sharing data "

last indonesian strains in LA data base , are 24/01/2007.. it s exact ?
 
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