Indonesia HUMAN Cases - March 26, 2008 to April 9, 2008

[Commonground]

Re: Indonesia HUMAN Cases - Mar/26/2008+

Re: Indonesia HUMAN Cases - Mar/26/2008+

Suspect AI Died
Senin, 07/04/2008

Mulyanti, 16, pasien suspect bird flu had finally blown out the last breath on Saturday (5/4) struck 16,00 WIB.
Mulyanti died after receiving the maintenance for three days in the Penyakit Infeksi Sulianti Soroso Hospital (RSPI-SS), in Jakarta Utara.
Yanti's body, the Mulyanti nickname arrived in the funeral parlour in Street Garuda Blok D2 Nomor 7,RT05/10,Perumahan Bumi Sawangan Indah, the Depok City, on Saturday night, struck 19,00 WIB. Yanti's Body was at once buried that same evening.
"Dari the hospital has been bathed and that same evening after being buried immediately was buried," Sutisna words, casualties's father, yesterday.
He said, beforehand did not have the matter that aroused suspicion in his child's illness.
"Previously my child was just very healthy, but suddenly his breath was felt crowded and feverish high," he said.

Now casualties's older brother, Suhandi explained, originally his brother only went to the doctor close to the house, because of only coughs and the fever and according to the doctor only experienced the stomach upset and laryngitis then.
He said, because never recovered Yanti had finally taken medicine to the Bahkti Yuda Hospital, Depok since Monday (31/3).
After receiving the maintenance for two nights, finally on Wednesday night (2/4) Yanti was reconciled to RSPI-SS, because of being suspected of suffering bird flu.
According to Suhandi, his residence environment was organised was neat enough, and only several residents who maintained birds.
In fact beforehand, the Mulyanti condition could be said to improve. According to a relative of casualties, Ugi, the Mulyanti condition increasingly good.
"Condition increasingly improved, but still quarantined in isolation space and was not yet permitted to come home," said Ugi that accompanied casualties during in RSPI-SS. Wali of the City Depok Nur Mahmudi Ismail that heard this news at once ordered the Pertanian Service to take the fast action on this case.

"Dinas agriculture must clean the environment around to turn off the bird flu virus in order to not spread increasingly spread," he revealed.
The section head the Health of the Animal and the Health of the Veteriner Community (Kesmavet) the Service of Pertanian Kota Depok, Deddy Sujadi said, in Yanti's residence territory was found several poultries belonging to the resident who died suddenly.
Therefore, his side also did rapid test in the location of casualties's housing.
From these results was found by the existence of the positive poultry bird flu, so as his side at once carried out the extermination against all the poultries belonging to this resident.
"As many as 28 chickens belonging to the resident around immediately was destroyed, because of results rapid test showed the poultry that was maintained this was positive bird flu," he said.
Deddy said, up to now his side is still being waiting for results of the test of the RSPI Sulianti Saroso side that his plan was just known today.
When results of the test stated Yanti died positive because of bird flu, then his side will destroy all the available poultries in the radius 200 metre from casualties's house.

http://www.seputar-indonesia.com/edisicetak/jawa-barat/suspect-ai-meninggal.html

 

[Commonground]

Re: Indonesia HUMAN Cases - Mar/26/2008+

Re: Indonesia HUMAN Cases - Mar/26/2008+

Ability to overcome Bird Flu Not Way of Doing

Jakarta, Kompas: Various policies of the government of dealing with the spreading of the bird flu virus or H5N1 did not go in the operational level.
As a result, casualties died continued to fall, in fact Indonesia occupied the first place of bird flu casualties that most in the world, at least 107 people died.
China and Vietnam, two countries that beforehand terjangkit the bird flu virus or avian influenza (AI) during 2003, currently in fact relative could control the spreading of this virus.
The number of casualties was infected and died under Indonesia.
On the other hand, in Indonesia, casualties were infected and died continued to improve, including the occurrence of the new case in this week in Padang (West Sumatra), Depok (West Java), and Tegal (Central Java).
"Some ability management not serious carried out," the member's words the Ahli Panel the Nasional Pengendalian Committee of Bird Flu and Menghadapi Pandemi Influenza Preparedness (Komnas FBPI), Mangku Sitepu.

http://www.kompas.co.id/kompascetak/read.php?cnt=.xml.2008.04.07.08490317&channel=2&mn=154&idx=154

 

[Commonground]

Re: Indonesia HUMAN Cases - Mar/26/2008+

Re: Indonesia HUMAN Cases - Mar/26/2008+

Negative, Result of the Blood Test Victim Suspek AI

The sample inspection of blood of a Tangerang inhabitant, Provinsi Banten, who was expected terjangkit the bird flu virus or avian influenza (AI) showed results of the negative.

"Results" of "his blood inspection were negative, but the patient continued to be treated intensively, the" Pemberantasan" broad headword and the Prevention of the Lingkungan Dinas Kesehatan Illness of the Tangerang City, Liza Puspadewi as being quoted by Antara, on Sunday (6/4).

As being reported beforehand, a woman had the initials Nur (45), the resident of the Village of Poncol Rt 05/08 the District Kunciran the Penang Subdistrict the Tangerang City, was expected suffered suspek bird flu and was treated in space of the bird flu isolation in the regional Public Hospital (RSUD) Tangerang from Friday (4/4) at dawn.
Pelayanan RSUD Tangerang Deputy Director, Bambang Wisnubroto said the sign of casualties headed was infected by bird flu like the high fever, breathless that was accompanied by the difficult cough and trombosit low.
The previous doctor decided to take the sample of casualties's blood to be checked in the Departemen Laboratory of the Health, Jakarta, but results of the negative or was indicated not terjangkit the deadly virus.

http://www.kompas.com/index.php/rea...8/negatif.hasil.tes.darah.penderita.suspek.ai

 

[Commonground]

Re: Indonesia HUMAN Cases - Mar/26/2008+

Re: Indonesia HUMAN Cases - Mar/26/2008+

The patient Tamiflu-Resistant was not yet found in Indonesia
Senin, 07 April 2008 | 17:54 WIB

Indonesia did not yet have the bird flu patient who was immune to tamiflu-medicine bird flu that was recommended by Food and Drug Administration (FDA) the United States.
"Possibly in the other country," said Director General Pengendalian of the Illness and Lingkungan I Nyoman Kandun Sanitation to the reporter in the Department of the Health, on Monday (7/4).
Jennifer McKimm-Breschkin, the researcher from Australia in 2007 stated the virus H5NI (the bird flu groove) in Indonesia was more insensitive 20-30 times in tamiflu than the virus that was same from Cambodia.
The deputy the Pengembangan Field of the Iptek Nasional Kementrian Negara Riset System and Tien R. Muchtadi Technology also indicated the possibility resisten the virus H5NI in tamiflu during the annual meeting of bird flu in Bali late last March.
According to Kandun, Departemen of the limiting Health of purchase access tamiflu so that consumption tamiflu exact the target, especially time and his dose.

http://www.tempointeraktif.com/hg/nasional/2008/04/07/brk,20080407-120637,id.html

 

[Commonground]

Re: Indonesia HUMAN Cases - Mar/26/2008+

Re: Indonesia HUMAN Cases - Mar/26/2008+

The resident of the Atmosphere was Still Negative Flu Burung
on Monday, April 07 2008 | 19:39 of WIB

The Interaktif TIME, Depok: results of the diagnosis against Mul, 16 years, the resident of the Atmosphere, Depok, that died last Saturday (5/4) still negative bird flu.
"Until this results were still negative," said Section Head Kesehatan of the City Depok Mien Hartati when being contacted the Time, on Monday (7/4).
However, Mien added results of this diagnosis could be still changing.
According to him, his side until this was still being waiting for results of the further inspection of the bird flu command post.
"Tomorrow (today) if having the development would I let know" said Mien.
Beforehand, Mul, that was treated for three days in the Penyakit Infeksi Sulianti Saroso Hospital, Jakarta Utara, it was suspected was affected by bird flu.
http://www.tempointeraktif.com/hg/jakarta/2008/04/07/brk,20080407-120657,id.html

 

[Commonground]

Re: Indonesia HUMAN Cases - Mar/26/2008+

Re: Indonesia HUMAN Cases - Mar/26/2008+

600 Poultry Kampung in Bukittinggi and Agam Destroyed
on Monday, April 07 2008 | 10:30 of WIB

The Interaktif TIME, Padang: To avoid the plague expansion of bird flu, for the last four days the Service of Peternakan West Sumatra destroyed 600 nonpedigreed chickens in three areas, that is the Ngarai Sianok Valley, Palupuh and Bukittinggi.

Kasubdin Bina Kesehatan of the Animal of Dinas Peternakan West Sumatra, Drh Erinaldi, to say for the time being the extermination of the chicken has been enough, because till at this time just the three areas that his chicken was affected by bird flu.

"Chicken was the free nonpedigreed chicken, so we guessed that every day one game with chickens that were affected by bird flu, so the limit of the crossing territory has been enough," he said today.

Beforehand, was based on results of the testing polymerase chain reaction (PCR) by taking mucus on the chicken throat that was done the Penyidikan Hall and the Veteriner Testing (BPPV) Bukittinggi, was found by 12 kept chickens the resident of the Ngarai Sianok Valley, Agam, was stated positive terjangkit the bird flu virus.
Moreover, was gotten by three cases of bird flu from the three areas, one of them struck the baby was 21 months old came from the Ngarai Sianok Valley that was positive bird flu and currently was treated in RSUP M. Djamil Padang.

 

[sharon sanders]

Re: Indonesia HUMAN Cases - Mar/26/2008+

Re: Indonesia HUMAN Cases - Mar/26/2008+

The resident of the Atmosphere was Still Negative Flu Burung
on Monday, April 07 2008 | 19:39 of WIB

The Interaktif TIME, Depok: results of the diagnosis against Mul, 16 years, the resident of the Atmosphere, Depok, that died last Saturday (5/4) still negative bird flu.
"Until this results were still negative," said Section Head Kesehatan of the City Depok Mien Hartati when being contacted the Time, on Monday (7/4).
However, Mien added results of this diagnosis could be still changing.
According to him, his side until this was still being waiting for results of the further inspection of the bird flu command post.
"Tomorrow (today) if having the development would I let know" said Mien.
Beforehand, Mul, that was treated for three days in the Penyakit Infeksi Sulianti Saroso Hospital, Jakarta Utara, it was suspected was affected by bird flu.
http://www.tempointeraktif.com/hg/jakarta/2008/04/07/brk,20080407-120657,id.html

Didn't one of the treating physicians report that this patient was positive?

 

[Commonground]

Re: Indonesia HUMAN Cases - Mar/26/2008+

Re: Indonesia HUMAN Cases - Mar/26/2008+

Florida1, there is more detail on this case in Post #140.
This is Mulyanti/Yanti (16) who just passed away. Apparently they have tested her twice, and both times it was negative.

 

[Gert van der Hoek]

Re: Indonesia HUMAN Cases - Mar/26/2008+

Re: Indonesia HUMAN Cases - Mar/26/2008+

From Padang, West Sumatra; Alifah Qamsah was tested positive; the other 2 still wait for the test results from Jakarta.

3 Bird Flu patients in Padang improved

on Monday, April 7 2008


Three patients suspect bird flu in the Hospital M. Jamil Padang today it was reported improves. Although being stated improved, they were not yet permitted to come home.

Alifah Qamsah or normally was called by Anisa (23 months) today was reported improved. He could have eaten, not the cough, cramps, and breathless.

"However, we did not yet permit and currently still was in isolation space, the" medic's" headword the RSUP Service M. Jamil, Irayanti when being met okezone, on Monday (7-4-2008).

Now Etriani (29), the nurse RSUP Bukittinggi that became the patient was expected by bird flu and Afifah (21 months), also was ascertained has improved. "Etriani could have walked small in the place, but was not yet permitted by us to go out of the room."

Whereas Afifah, could have eaten and communicated with his mother, he stated.

http://news.okezone.com/index.php/ReadStory/2008/04/07/1/98282/3-pasien-flu-burung-di-padang-membaik

 

[Gert van der Hoek]

Re: Indonesia HUMAN Cases - Mar/26/2008+

Re: Indonesia HUMAN Cases - Mar/26/2008+

On Monday, April 07 2008

Menkes: Mulyanti died Not because of Bird Flu

The Health Minister (Menkes), Siti Fadilah Supari said, was based on results of the inspection, Mulyanti (16), the Depok resident who died, evidently not because of being attacked by the bird flu virus, but suffered the tuberculosis illness (the TB or TB).

After being carried out by the results inspection of the negative was attacked by the bird flu virus, he said after giving the public's lecture, with the Avian Diplomacy theme: Facing The Challenge of Technology and Global Capitalism, in FISIP-UI, Depok, on Monday.

Beforehand Mulyanti (16) the Depok resident Street Garuda the Bloc D2 ***, RT05/RW. 10, Earth Housing the Beautiful Atmosphere, died, and was expected because of bird flu on the Saturday (5-4) struck 16,00 WIB. Mulyanti for three days in the Sulianti Soroso Infection Hospital (RSPI-SS), in Jakarta North.

Menkes said, that was detected dying because of contracting bird flu of only two people that is in Padang, West Sumatra and Subang, West Java.
The resident of the other area that died not because of bird flu, he said.

According to him, at this time had 31 provinces in Indonesia that his poultry was stated positive bird flu, and three provinces (Jakarta, Banten and West Java) the case of his bird flu still quite high compared with the other province.

So, said he, needed the national program cleansed the poultry farm of the settlement and destroyed the poultry that was infected by bird flu.
The poultry that was in a radius of 1 kilometre must segara was destroyed, he said.

He also said various policies of dealing with the spreading of the bird flu virus or H5N1 still continued to be carried out. All the policy programs continued to be undertaken, he said.

Beforehand, the Section Head the Health of the Animal and the Community of Veteriner Kota Depok, Deddy Sudjadi said, in Yanti's place territory was found several poultries belonging to the resident who died suddenly.

His side also did rapid test in the location of casualties's housing.
From these results was found by the existence of the positive poultry bird flu, so as his side at once carried out the extermination against all the poultries belonging to this resident.

28 chickens belonging to the resident around immediately was destroyed, because of results rapid test showed his kept poultry was positive, he said.
Was based on the note of the Depok Municipal Government, beforehand three Depok residents who died resulting from bird flu.

First during 2006, namely Yasinto (22 years), the resident of the Pangkalan Jati District, Kecamatan Limo and Yuliana, (30) the resident of the Cilangkap District, Kecamatan Cimanggis, as well as Muhammad Ibnu Yusuf (9) the Pancoranmas resident who died at the end of January 2008.

http://www.kapanlagi.com/h/0000221578.html

 

[Gert van der Hoek]

Re: Indonesia HUMAN Cases - Mar/26/2008+

Re: Indonesia HUMAN Cases - Mar/26/2008+

Two patients Suspect Bird Flu in Padang Negative

7 April 2008

Etriani, 29 and Asyifa, 2, that was treated in the Hospital M. Djamil Padang was stated by the negative was infected by the virus H5N1.

That was ascertained after the hospital side accepted results of the blood test both of them from Kesehatan Research And Development (Balitbangkes) the Department of the RI Health. Was like this it was said the Head of the Medik Service RS M. Djamil Padang Irayanti, on Monday (7-4).

According to him, the condition for the two patients at this time continued to
improve. The high fever, the cough and breathless that beforehand was suffered by the two patients gradually decreased.

At this time, both of them were treated intensive in installation space treated inap (Irna) C the III RS floor internal disease M. Djamil was neighbouring with AQ, 2, the other bird flu patient.

Etriani was the nurse in the Stroke Nasional Hospital (RSSN) the Bukittinggi City. He underwent the maintenance in RS M. Djamil Padang since Sunday (30-3).

As for Asyifa began to undergo the maintenance in RS M. Djamil Padang since Tuesday (1-4) then.

In the meantime, the AQ condition, the positive patient bird flu that also was treated in RS M. Djamil Padang continued to improve.
Pre-schoolers who came from Nagari (the village) Sianok, Kecamatan IV Koto, Kabupaten Agam could have at this time eaten and no longer experienced the fever, the cough and cramps.

Irayanti said, although the Alifa condition continued to improve, the team of the doctor did not yet permit him to come home.

These pre-schoolers will be permitted to come home after his condition really was restored and results of the last blood test were stated by the negative contained the virus avian influenza.

AQ was the reconciliation patient from the Stroke Nasional Hospital (RSSN) the Bukittinggi City. He began to be treated in RS M. Djamil Padang since Monday (24-3) then. He was stated positive was infected by bird flu after the Service of Kesehatan West Sumatra accepted results of the test of pre-school blood from Balitbangkes Departemen of the RI Health, on Wednesday (2-4) then.

http://www.koranindonesia.com/2008/04/07/dua-pasien-suspect-flu-burung-di-padang-negatif/

 

[Commonground]

Re: Indonesia HUMAN Cases - Mar/26/2008+

Re: Indonesia HUMAN Cases - Mar/26/2008+

Etriani, 29 and Asyifa, 2, that was treated in the Hospital M. Djamil Padang was stated by the negative was infected by the virus H5N1.

I do not have an onset of symptoms for
Alifa (positive)
Asyifa (negative)
Etriani (negative)

I notice the article does not mention what they do have.
I may have missed the onset somewhere along the line?
If anyone has that info, please post it here.

 

[Gert van der Hoek]

Re: Indonesia HUMAN Cases - Mar/26/2008+

Re: Indonesia HUMAN Cases - Mar/26/2008+

I do not have an onset of symptoms for
Alifa (positive)
Asyifa (negative)
Etriani (negative)

I notice the article does not mention what they do have.
I may have missed the onset somewhere along the line?
If anyone has that info, please post it here.

Here are some pieces of the puzzle:

In Bukit Tinggi ALQ (F, 1 year) positive bird flu was the resident of Lembah Ngarai Sianok. Apart from the fever, the cough, pilek and breathless, ALQ also experienced diarrhoea. The sign of early began apparently on March 17 2008 and ALQ was carried to RSUP Stroke Bukittinggi (22/03/08 ) before being treated in RS M. Djamil Padang on March 24 2008.

Press release Dep of Health; http://www.depkes.go.id/index.php?option=news&task=viewarticle&sid=3065


According to Eva (40), Bibi Anisa, his nephew has been feverish and coughs since Saturday last March 13. At that time the older brother Anisa, Edi Satria, was just carried to RSUD Bukittinggi. "But his older brother died when being treated," said Eva.

http://www.flutrackers.com/forum/showpost.php?p=144347&postcount=14


Al (2), the patient suspect bird flu that was treated in the room of the Instalasi Rawat Inap Isolation (Irna) C Penyakit Dalam RSUP M. Djamil Padang, up until yesterday his condition was still critical.
The patient of Hospital reconciliation of Ahmad Mukhtar Bukittinggi this was suspected bird flu, because of the sign of his illness resembled bird flu.

This assumption was strengthened by his older brother's situation, Ed (21).
That just recently, he died with the same sign.
At this time the side RSUP M. Djamil Padang sent the sample of the patient's blood to Research And Development Department of Health RI for the further inspection the Patient who was the child to four from four related this, was the daughter from "Zu" and "Fa", the resident of the Sianok Kota Bukitinggi Gorge.
At this time his condition was still critical with the temperature of his body on 38 levels, even yesterday the night could experience cramps cramps and breathless.

"Ak" (18 ) one of casualties's cousins said that two days after his first older brother of Alm "Ed" (21) was sick, he also experienced was sick.
Only his two parents supposed "Al" only common fevers.
Moreover at that time his parents were busy treating his older brother who was treated in RS Ahmad Mukhtar (RSAM) Bukitinggi.

http://www.flutrackers.com/forum/showpost.php?p=144574&postcount=29


The medical staff RSSN Suspect Flu Burung

"Et" (29), the medical staff in the Internal Disease ward in the Stroke Nasional Hospital (RSSN) Bukittinggi, on Sunday (30/3) around struck 02,00 WIB, was forced to be run off with to RS M. Djamil Padang, because suffered hot high like the sign suspect bird flu."Et was transported by the RSSN ambulance, was accompanied by three nurses and two doctors who wore the robe, the mask and impermeable eyes glasses."

http://www.flutrackers.com/forum/showpost.php?p=144885&postcount=40

 

[Commonground]

Re: Indonesia HUMAN Cases - Mar/26/2008+

Re: Indonesia HUMAN Cases - Mar/26/2008+

Thank you so much Dutchy.
So we know that Alifa was symptomatic around 3/11 and wasn't admitted to M. Djamil Hospital until the 24th. I can't believe she made it, although I am extremely happy for it.

Now Asyifa also went quite a while before any Tamiflu. From 3/17 (or 3/13) until 3/22 (if she received it at RSUP Bukittingi).

The nurse, Etriani treated Edi, who was admitted on the 11th.
Etriani was admitted on the 30th. And Etriani was run off with "just" a very high temperature. So she didn't wait long.

Hmmmmm....

 

[Gert van der Hoek]

Re: Indonesia HUMAN Cases - Mar/26/2008+

Re: Indonesia HUMAN Cases - Mar/26/2008+

From Padang, West Sumatra

Two patients Suspect the Bird Flu Negative, "Irayanti: Still was waiting for Second results"

After being waiting almost one week, results of the Polimerace Chain Reaction inspection (PCR) first, two patients suspect bird flu in RSUP M. Djamil Padang was stated by the negative by Research And Development Department of Health RI. Meskipun Demikian, the two patients were still getting the intensive maintenance in the room of the isolation of Irna C Penyakit Dalam RSUP M. Djamil Padang.

In accordance with the procedure continue to him the patient was permitted to come home and to be stated healthy, after three times produced by the PCR test stated the patient suspect was stated by the negative.

Before results of PCR went out, explained Irayanti, before results rapid test from RSUP M. Djamil Padang also stated the negative.
However in accordance with the handling procedure suspect bird flu, then must be carried out by the PCR test totalling three times.
Because of this PCR test results were more accurate, sensitive and specific compared with results rapid test.

Till at this time his side was still being waiting produced by PCR that was second and third from Research And Development Department of Health RI. Because the taking of blood was for the second and third test carried out periodically, after the taking of the sample of blood for the first test.

At this time the condition for two suspect this bird flu patient increasingly showed the pleasing development.

If beforehand Afifah could suffer hot high that was accompanied by cramps, at this time the temperature of his body again was normal.

Even so with Etriani that initially could experience the fever and the cough, at this time his condition has also begun to be restored.

Now Alifah that was stated positive produced by PCR first him, but his condition continued to improve.

At this time he no longer uses the medical implement to help breathing like oxygen and the implement sonde to help put food into his body.

The three patients were treated in one room of the isolation RSUP M. Djamil Padang. Only for the patient who was stated positive like Alifah the room of his maintenance was separated with two other patients.

However from the aspect of their maintenance continued to get the same maintenance.

The nurse and the family who entered this room must use the protection implement himself (APD). Among them, used sterile clothes of two layers, the mask and the cover of the head.

All that was carried out to prevent spread him the infection that was carried from outside the room to the patient. Because of the condition for the patient at this time still in the susceptible and weak situation.

http://www.padangekspres.co.id/index.php?option=com_content&task=view&id=2544&Itemid=27

 

[Commonground]

Re: Indonesia HUMAN Cases - Mar/26/2008+

Re: Indonesia HUMAN Cases - Mar/26/2008+

After being waiting almost one week, results of the Polimerace Chain Reaction inspection (PCR) first, two patients suspect bird flu in RSUP M. Djamil Padang was stated by the negative by Research And Development Department of Health RI. Meskipun Demikian,

Here's what the NEJM said:

NEJM - Update on Avian Influenza A (H5N1) Virus Infection in Humans

Excerpt:

Laboratory Diagnosis

Detection of viral RNA by means of conventional or real-time reverse-transcriptase polymerase chain reaction remains the best method for the initial diagnosis of influenza A (H5N1).52 These assays can provide results within 4 to 6 hours and can be performed under biosafety level 2 conditions. The genetic variability of influenza A (H5N1) viruses7,8 calls for frequent updating of primers and probes. Consequently, access to sequences from recent influenza A (H5N1) viral isolates is essential. To detect other influenza A virus infections and reduce false negative results due to mutations in the H5 hemagglutinin gene, a conserved influenza A gene (e.g., matrix or nucleoprotein) should also be targeted.

Diagnostic yields are higher with throat specimens than with nasal swabs because of higher viral loads of influenza A (H5N1) in the throat.1,3 However, nasal swabs are useful for detecting human influenza viruses, so collection of both specimens is recommended. If they are available, tracheal aspirates have higher viral titers and yields than specimens from the upper respiratory tract.3 Negative results in single respiratory specimens do not rule out influenza A (H5N1) virus infection,21 and repeated collection of multiple specimen types is recommended.52 Previous antiviral treatment may reduce the diagnostic yield. Detection of influenza A (H5N1) viral RNA in feces or blood may provide prognostic information,3 but it has lower diagnostic sensitivity than influenza A (H5N1) viral RNA in respiratory specimens.

Commercially available rapid assays for influenza-antigen detection have poor clinical sensitivity for the detection of influenza A (H5N1) virus (Table 2 of the Supplementary Appendix),1,20,21 and they do not differentiate between human and avian subtypes of influenza A viruses. Although rapid antigen tests have similar analytic sensitivity for detecting human and avian influenza A (H5N1) viruses, they require 1000 times higher levels of virus than viral cultures to be positive.53

The detection of anti-H5 antibodies is essential for epidemiologic investigations and may provide retrospective diagnostic confirmation in patients. Seroconversion generally occurs 2 to 3 weeks after infection. Microneutralization assays are the most reliable methods for detecting antibodies to avian viruses, but they are labor-intensive and require biosafety level 3 facilities and appropriate strains of influenza A (H5N1) viruses. As compared with initial samples, elevations of four times or more or single titers of 1:80 or more in convalescent-phase samples are considered to be diagnostic.52 Modified nonpathogenic influenza A (H5N1) virus generated by reverse genetics or lentivirus pseudotyped with H5 hemagglutinin54 may provide alternatives for performing neutralization tests in biosafety level 2 facilities. Hemagglutination-inhibition assays with the use of horse erythrocytes show promising results but require further validation.

http://www.flutrackers.com/forum/showthread.php?p=125122#post125122

 

[Oracle]

Re: Indonesia HUMAN Cases - Mar/26/2008+

Re: Indonesia HUMAN Cases - Mar/26/2008+

This would appear to be an extremely important cluster of cases, certainly worthy of international study (MUCH more so than the widely publicized Jiangxi China Father-Son case that was sadly lacking in vital details, but apparently worth writing up in Lancet).

As pointed out above, rigorous testing is required to determine with a degree of confidence, whether or not H5N1 infection is present. Antiviral drug treatment complicates detection, obviously.

The nurse's case suggests that family genetics may not be a dominant feature of susceptibility. Locality, however, is a dominant feature.

Indonesian public health officials should retain the exceptionally important patient (all, not just viral) samples obtained from this cluster of patients, storing them carefully for re-analysis.

Now would be a VERY good time to capture index and associated case exposure details.

We will be revisiting this cluster for in-depth analysis, later on.

 

[Laidback Al]

Re: Indonesia HUMAN Cases - Mar/26/2008+

Re: Indonesia HUMAN Cases - Mar/26/2008+

Official (final?) report from DEPKES about Mulyanti . . . .

MY Warga Depok Negatif Flu Burung on April 08 2008

MY (P, 16 years) the Depok resident of Provinsi West Java, the patient who was expected (suspek) bird flu that was treated in RS Penyakit Infeksi Sulianti Saroso Jakarta, was based on the inspection of the Body laboratory of Litbangkes Department of Health RI was stated by the bird flu negative.
The patient suspek this bird flu died on April 2 2008 struck 23,35 WIB because of the other illness not because of bird flu.
Was like this information that was accepted by the Centre of Publik Communication of the Flu Burung Command Post, Directorate General Pengendalian of the Illness and Lingkungan Departemen Sanitation of the Health, on April 4 2008. . . .

http://www.depkes.go.id/index.php?option=news&task=viewarticle&sid=3073

 

[Gert van der Hoek]

Re: Indonesia HUMAN Cases - Mar/26/2008+

Re: Indonesia HUMAN Cases - Mar/26/2008+

On Monday, April 07 2008

Menkes: Mulyanti died Not because of Bird Flu

The Health Minister (Menkes), Siti Fadilah Supari said, was based on results of the inspection, Mulyanti (16), the Depok resident who died, evidently not because of being attacked by the bird flu virus, but suffered the tuberculosis illness (the TB or TB).

After being carried out by the results inspection of the negative was attacked by the bird flu virus, he said after giving the public's lecture, with the Avian Diplomacy theme: Facing The Challenge of Technology and Global Capitalism, in FISIP-UI, Depok, on Monday.

Beforehand Mulyanti (16) the Depok resident Street Garuda the Bloc D2 ***, RT05/RW. 10, Earth Housing the Beautiful Atmosphere, died, and was expected because of bird flu on the Saturday (5-4) struck 16,00 WIB. Mulyanti for three days in the Sulianti Soroso Infection Hospital (RSPI-SS), in Jakarta North.

Menkes said, that was detected dying because of contracting bird flu of only two people that is in Padang, West Sumatra and Subang, West Java.
The resident of the other area that died not because of bird flu, he said.

According to him, at this time had 31 provinces in Indonesia that his poultry was stated positive bird flu, and three provinces (Jakarta, Banten and West Java) the case of his bird flu still quite high compared with the other province.

So, said he, needed the national program cleansed the poultry farm of the settlement and destroyed the poultry that was infected by bird flu.
The poultry that was in a radius of 1 kilometre must segara was destroyed, he said.

He also said various policies of dealing with the spreading of the bird flu virus or H5N1 still continued to be carried out. All the policy programs continued to be undertaken, he said.

Beforehand, the Section Head the Health of the Animal and the Community of Veteriner Kota Depok, Deddy Sudjadi said, in Yanti's place territory was found several poultries belonging to the resident who died suddenly.

His side also did rapid test in the location of casualties's housing.
From these results was found by the existence of the positive poultry bird flu, so as his side at once carried out the extermination against all the poultries belonging to this resident.

28 chickens belonging to the resident around immediately was destroyed, because of results rapid test showed his kept poultry was positive, he said.
Was based on the note of the Depok Municipal Government, beforehand three Depok residents who died resulting from bird flu.

First during 2006, namely Yasinto (22 years), the resident of the Pangkalan Jati District, Kecamatan Limo and Yuliana, (30) the resident of the Cilangkap District, Kecamatan Cimanggis, as well as Muhammad Ibnu Yusuf (9) the Pancoranmas resident who died at the end of January 2008.

http://www.kapanlagi.com/h/0000221578.html

A report stating the older brother of Mulyanti is "breathless", could be TB too. Can't translate it now.



Kakak korban sesak nafas

5-Apr-2008

PENGASINAN, MONDE: Kondisi korban suspect flu burung, Myi (16), yang kini dirawat secara intensif diruang isolasi RSPI Sulianti Saroso mulai membaik, tapi kakaknya justru mulai batuk dan sesak nafas?

Kerabat keluarga korban, Ugi yang turut mengikuti perkembangan kondisi kesehatan korban di rumah sakit,mengatakan hal itu. ?Kondisinya makin membaik, tetapi masih dikarantina di ruang isolasi dan belum diperbolehkan pulang,? tuturUgi yang merupakan teman kerja ayah korban.

Sebelumnya, Rabu (2/4) korban dinyatakan suspect flu burung oleh RS Bakti Yudha dan langsung dirujuk keRS Sulianti Saroso karena keterbatasan alat untuk penanganan flu burung di rumah sakit tersebut.

Sementara itu, berdasarkan keterangan Ugi, kakak korban yang berinisial Ai kini kondisinya mulai mengalamipenurunan disertai batuk dan sesak napas, sama persis dengan keluhan awal yang diderita adiknya.

?Kakaknya kondisinya kini juga menurun, gejala yang dialaminya juga sama seperti batuk-batuk dan sesaknapas, saya dan ayahnya sudah menyuruhnya ke rumah sakit tetpai hingga kini sepertinya belum dilakukan,?terangnya.

Saat Monde mencoba melihat kondisi Ai di kediamannya, rumahnya tampak sepi dan tidak diketemukankeberadaan Ai saat itu. Para tetangga yang ditemui Monde juga tidak mengetahui keberadaannya.

?Dari tadi sih saya belum lihat adaorang, mungkin pergi dari tadi pagi kali,? ujar salah seorang tetangganya.Menurut keterangan Ugi, kakaknya telah melakukan pengobatan di salah satu balai pengobatan danmengatakan kondisinya tidak apa-apa walaupun sering batuk-batuk.

?Saya dan ayahnya ingin dia cek ke rumah sakit intinya supaya tahu sakit apa, biar jelas, tetapi orangnyatetap nggak mau, padahal gejalanya hampir sama dengan adiknya,? tegasnya.Sementara itu, Camat Sawangan Usman Haliyana beserta Lurah Pengasinan Muksin Mawardi melakukanpengecekan terhadap situasi wilayah RT 01/RW 03 yang didapati unggas positif flu burung, kemarin.

?Memang unggas yang positif flu burung tersebut merupakan peliharaan warga yang proses pemeliharaanyamemang kurang baik dan sering dibiarkan lepas di lingkungan,? tuturnya.Untuk itu ia mengimbau kepada masyarakat Pengasinan di sekitar wilayah tersebut untuk memelihara danmengandangkan unggas peliharaanya secara baik, dan diberikan perawatan secara intensif.

Dari setidaknya 16 pintu masuk unggas yang akan ke Kota Depok hanya satu pintu saja yang saat inimendapatkan penjagaan ketat pengawasan dari Dinas Pertanian (Distan).Hal itu dituturkan oleh Kepala Seksi Kesehatan Hewan dan Kesehatan Masyarakat veteriner (Kesmavet)Deddy Sujadim kepada Monde di ruang kerjanya, kemarin.

Dari 12 pintu masuk itu lanjut Deddy, masing-masing berbatasan dengan Provinsi Banten, Jakarta dan berbatasan langsung dengan Jawa Barat.Pintu masuk yang dijaga saat ini merupakan pintu yang berlokasi di area Sawangan, dimana nertugasmelakukan pengamatan unggas dari wilayah Bogor dan Tangerang.

Keterbatasan itu lanjut Deddy karena masih terbatasnya pegawai dan armada pelengkapnya yang dimilikioleh Pemkot Depok saat ini.Pun demikian Deddy menuturkan, selama ini pihaknya telah melakukan pencegahan terhadap merebaknyaflu burung dengan cara yang lain.

Di antaranya, katanya, dengan melakukan biosecurity, yakni melakukan penyemprotan ayam dengandesinfektan di lokasi pemotongan. Kepada sejumlah pengusaha potong unggas pun dianjurkan untuk takmemotong ayam yang telah mati atau pun yang sedang sakit .

Deddy pun mengimbau masyarakat untuk tetap berprilaku bersih dan sehat karena pada dasarnya virusH5N1 akan mati hanya dengan detergen.(why/ina)

http://www.monitordepok.com/pdf/berita-utama/19123.html.

 

[Commonground]

Re: Indonesia HUMAN Cases - Mar/26/2008+

Re: Indonesia HUMAN Cases - Mar/26/2008+

Post #158

[Note, this article was written before Myi passed away]

Casualties's older brother crowded breath

5-April-2008

The condition for casualties suspect bird flu, Myi (16), that currently is treated intensively diruang the RSPI Sulianti Saroso isolation began to improve, but his older brother precisely began the cough and breathless

Relatives of casualties's family, Ugi that took part in following the development of the condition for the health of casualties in the hospital, said that.
"the Condition increasingly improved, but still quarantined in isolation space and was not yet permitted to come home," uttered Ugi that was the colleague of casualties's father.


Beforehand, on Wednesday (2/4) casualties were stated suspect bird flu by RS Bakti Yudha and at once was reconciled to RS Sulianti Saroso because of the limitations of the implement for the handling of bird flu in this hospital.

In the meantime, was based on Ugi information, casualties's older brother who has the initials Ai currently his condition began to experience decline was accompanied by the cough and breathless, equally precisely with the beginning complaint that was suffered by his brother.


"Older sibbling his condition currently also descends, the sign that was experienced by him also same like coughs and crowded breathing, I and his father have told him to the hospital but up to now apparently was not yet carried out," obviously him.

When Monde tried to see the Ai condition in his residence, his house appeared quiet and not found presence of Ai at that time.
The neighbours who were met by Monde also did not know his existence.
"From before I did not yet see to be people, possibly had gone for some time the time morning," said a neighbor. According to Ugi information, his older brother carried out medical treatment in one of the medical clinics and to say his condition it's alright although often coughs.

"I and his father wanted him the cheque to the hospital basically to knew was sick what, although clear, but person definite not wanted, in fact his sign almost was the same as his brother," clear.

Meanwhile, the Sub-district Head the Usman Haliyana Atmosphere as well as the Village Head the Muksin Mawardi Pickling carry out looking into towards the territory situation of RT 01/RW 03 that was found the positive poultry bird flu, yesterday.
"Indeed the positive poultry this bird flu was kept the resident that the process pemeliharaanyamemang not better and often was left free in the environment," he said.

So he made a plea to the Pickling community around this territory to maintain danmengandangkan the poultry peliharaa him well, and was given by the maintenance intensively.
From at least 16 poultry entrances that would to the Depok City of only one door that during this find the tight guarding of the supervision from the Pertanian Service (Distan) .Hal that was said by the Section Head the Health of the Animal and the Health of the Community veteriner (Kesmavet) Deddy Sujadim to Monde in his office, yesterday.
From 12 entrances continued Deddy, respectively shared a border with the Banten Province, Jakarta and shared directly a border with Java Barat. Gate entered that was minded at this time was the gate that was located in the area of the Sawangan, where nertugasmelakukan observation of the poultry from the Bogor territory and Tangerang.

The limitations continued Deddy because still the shortage of the official and his supplementary fleet that dimilikioleh the Depok Municipal Government during ini. Pun was like this Deddy said, uptil now his side carried out the prevention against merebaknyaflu birds by means of that was other.
Among them, he said, with did biosecurity, that is carrying out spraying of the chicken dengandesinfektan in the location of the reduction.
To several piece businessmen of the poultry then was recommended to takmemotong the chicken that died or that was sick.
Deddy then appealed to the community to continue to berprila I was clean and healthy because basically the virus H5N1 will die only with detergent.

http://www.monitordepok.com/pdf/berita-utama/19123.html.