INDONESIA - AVIAN INFLUENZA SEROSURVEY

[Laidback Al]

AVIAN INFLUENZA, HUMAN (92): INDONESIA, SEROSURVEY
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A ProMED-mail post
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International Society for Infectious Diseases <HTTP: www.isid.org>
Date: Tue 5 Jun 2007
From: Teguh Prajitno
<TEGUHYP@JAPFACOMFEED.CO.ID>

re: Avian influenza, human (91): veterinarians 20070604.1813
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I just want to make a comment on the status of poultry workers and veterinarians exposed to avian influenza virus (AIV). We have made most probably the largest blood sampling campaign among 1000 of our workers and veterinarians who were exposed to the H5N1 outbreak in 2005 and 2006 and were involved in culling, stamping out and composting activities in Indonesia. Blood samples were tested in the WHO-reference lab at Queen Mary Hospital in Hong Kong, and only 2 workers showed [evidence of] H5N1 infection. [These] blood samples were tested against Indonesian H5N1 virus isolates from 2005/2006.
I have been told that it is not easy to get infected by H5N1 [avian influenza virus]. Using HI [haemagglutination inhibition?] test mostly will give (false) positive results. Please clarify what tests have been used in the study in the US.
--
communicated by:
Dr Teguh Y Prajitno
PT Multibreeder Adirama Indonesia
A Japfa Comfeed Company
<TEGUHYP@JAPFACOMFEED.CO.ID>
[The data cited by Dr. Prajitno are unique and supported by the general observation that few people involved in poultry rearing, breeding, and culling in the H5N1 epidemic areas have been victims of the disease.
ProMED-mail welcomes the opportunity to communicate this information. It is possible that (as suggested by Dr Prajitno) the outcome of such surveys is affected by the method of assay and that this may be the reason for the difference between the American and the Indonesian results. ProMED-mail does not yet have access to the July issue of Clinical Infectious Diseases and cannot inform Dr Prajitno of the assay procedure used in the American study. We hope that an interested reader will be able to respond to his request. - Mod.CP]
[see also:
Avian influenza, human (91): veterinarians 20070604.1813]
..................cp/ejp/sh

http://www.promedmail.org/pls/prome..._BACK_PAGE,F2400_P1001_PUB_MAIL_ID:1000,37719

 

[Shannon Bennett]

Re: INDONESIA - AVIAN INFLUENZA SEROSURVEY

It is Vietnam and the strain was not one that was particularly virulent however, I find it absolutely fascinating that when other strains do infect humans they are able to be passed within limits to family members. So, is it the strain or is it extremely close proximity or, is it something else that enables some to be infected while those who work on a daily basis with disease laden birds to avoid H5N1?

 

[AlaskaDenise]

Re: INDONESIA - AVIAN INFLUENZA SEROSURVEY

....is it something else that enables some to be infected while those who work on a daily basis with disease laden birds to avoid H5N1?

As in children living with livestock have fewer allergies?

The part of our immune system that activates upon exposure to livestock might be coming into play.

Is it possible that the poultry carry enough segments of various AIs that the workers produce some immunity to the commonly conserved parts of AI?

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