tetano
Editor, Senior Moderator
Indian J Med Res
. 2020 Jul 22.
doi: 10.4103/ijmr.IJMR_1788_20. Online ahead of print.
Clinico-demographic profile & hospital outcomes of COVID-19 patients admitted at a tertiary care centre in north India
Anant Mohan[SUP] 1 [/SUP], Pawan Tiwari[SUP] 1 [/SUP], Sushma Bhatnagar[SUP] 2 [/SUP], Ankit Patel[SUP] 1 [/SUP], Abhishek Maurya[SUP] 1 [/SUP], Lalit Dar[SUP] 3 [/SUP], Sourabh Pahuja[SUP] 1 [/SUP], Rakesh Garg[SUP] 2 [/SUP], Nishkarsh Gupta[SUP] 2 [/SUP], Biswajeet Sahoo[SUP] 4 [/SUP], Ritu Gupta[SUP] 5 [/SUP], Ved Prakash Meena[SUP] 6 [/SUP], Saurabh Vig[SUP] 2 [/SUP], Anuja Pandit[SUP] 2 [/SUP], Saurabh Mittal[SUP] 1 [/SUP], Karan Madan[SUP] 1 [/SUP], Vijay Hadda[SUP] 1 [/SUP], Tanima Dwivedi[SUP] 4 [/SUP], Aashish Choudhary[SUP] 3 [/SUP], Megha Brijwal[SUP] 3 [/SUP], Manish Soneja[SUP] 6 [/SUP], Randeep Guleria[SUP] 7 [/SUP], Brajesh Ratre[SUP] 2 [/SUP], Balbir Kumar[SUP] 2 [/SUP], Shweta Bhopale[SUP] 2 [/SUP], Smriti Panda[SUP] 8 [/SUP], Angel Rajan Singh[SUP] 9 [/SUP], Sheetal Singh[SUP] 5 [/SUP], Laxmitej Wundavalli[SUP] 5 [/SUP]
Affiliations
Abstract
Background & objectives: : In December 2019, a novel coronavirus (SARS-CoV-2) emerged in China and rapidly spread globally including India. The characteristic clinical observations and outcomes of this disease (COVID-19) have been reported from different countries. The present study was aimed to describe the clinico-demographic characteristics and in-hospital outcomes of a group of COVID-19 patients in north India.
Methods: : This was a prospective, single-centre collection of data regarding epidemiological, demographic, clinical and laboratory parameters, management and outcome of COVID-19 patients admitted in a tertiary care facility in north India. Patient outcomes were recorded as death, discharge and still admitted.
Results: : Data of 144 patients with COVID-19 were recorded and analyzed. The mean age of the patients was 40.113.1 yr, with 93.1 per cent males, and included 10 (6.9%) foreign nationals. Domestic travel to or from affected States (77.1%) and close contact with COVID-19 patients in congregations (82.6%) constituted the most commonly documented exposure. Nine (6.3%) patients were smokers, with a median smoking index of 200. Comorbidities were present in 23 (15.9%) patients, of which diabetes mellitus (n=16; 11.1%) was the most common. A significant proportion of patients had no symptoms (n=64; 44.4%); among the symptomatic, cough (34.7%) was the most common symptom followed by fever (17.4%) and nasal symptoms (2.15%). Majority of the patients were managed with supportive treatment with hydroxychloroquine and azithromycin given on a case-to-case basis. Only five (3.5%) patients required oxygen supplementation, four (2.8%) patients had severe disease requiring intensive care, one required mechanical ventilation and mortality occurred in two (1.4%) patients. The time to reverse transcription-polymerase chain reaction (RT-PCR) negativity was 16-18 days.
Interpretation & conclusions: : In this single-centre study of 144 hospitalized patients with confirmed COVID-19 in north India, the characteristic findings included younger age, high proportion of asymptomatic patients, long time to PCR negativity and low need for intensive care unit care.
Keywords: Clinico-epidemiologic - cough - COVID-19 - north India - outcome - prospective.
. 2020 Jul 22.
doi: 10.4103/ijmr.IJMR_1788_20. Online ahead of print.
Clinico-demographic profile & hospital outcomes of COVID-19 patients admitted at a tertiary care centre in north India
Anant Mohan[SUP] 1 [/SUP], Pawan Tiwari[SUP] 1 [/SUP], Sushma Bhatnagar[SUP] 2 [/SUP], Ankit Patel[SUP] 1 [/SUP], Abhishek Maurya[SUP] 1 [/SUP], Lalit Dar[SUP] 3 [/SUP], Sourabh Pahuja[SUP] 1 [/SUP], Rakesh Garg[SUP] 2 [/SUP], Nishkarsh Gupta[SUP] 2 [/SUP], Biswajeet Sahoo[SUP] 4 [/SUP], Ritu Gupta[SUP] 5 [/SUP], Ved Prakash Meena[SUP] 6 [/SUP], Saurabh Vig[SUP] 2 [/SUP], Anuja Pandit[SUP] 2 [/SUP], Saurabh Mittal[SUP] 1 [/SUP], Karan Madan[SUP] 1 [/SUP], Vijay Hadda[SUP] 1 [/SUP], Tanima Dwivedi[SUP] 4 [/SUP], Aashish Choudhary[SUP] 3 [/SUP], Megha Brijwal[SUP] 3 [/SUP], Manish Soneja[SUP] 6 [/SUP], Randeep Guleria[SUP] 7 [/SUP], Brajesh Ratre[SUP] 2 [/SUP], Balbir Kumar[SUP] 2 [/SUP], Shweta Bhopale[SUP] 2 [/SUP], Smriti Panda[SUP] 8 [/SUP], Angel Rajan Singh[SUP] 9 [/SUP], Sheetal Singh[SUP] 5 [/SUP], Laxmitej Wundavalli[SUP] 5 [/SUP]
Affiliations
- PMID: 32773414
- DOI: 10.4103/ijmr.IJMR_1788_20
Abstract
Background & objectives: : In December 2019, a novel coronavirus (SARS-CoV-2) emerged in China and rapidly spread globally including India. The characteristic clinical observations and outcomes of this disease (COVID-19) have been reported from different countries. The present study was aimed to describe the clinico-demographic characteristics and in-hospital outcomes of a group of COVID-19 patients in north India.
Methods: : This was a prospective, single-centre collection of data regarding epidemiological, demographic, clinical and laboratory parameters, management and outcome of COVID-19 patients admitted in a tertiary care facility in north India. Patient outcomes were recorded as death, discharge and still admitted.
Results: : Data of 144 patients with COVID-19 were recorded and analyzed. The mean age of the patients was 40.113.1 yr, with 93.1 per cent males, and included 10 (6.9%) foreign nationals. Domestic travel to or from affected States (77.1%) and close contact with COVID-19 patients in congregations (82.6%) constituted the most commonly documented exposure. Nine (6.3%) patients were smokers, with a median smoking index of 200. Comorbidities were present in 23 (15.9%) patients, of which diabetes mellitus (n=16; 11.1%) was the most common. A significant proportion of patients had no symptoms (n=64; 44.4%); among the symptomatic, cough (34.7%) was the most common symptom followed by fever (17.4%) and nasal symptoms (2.15%). Majority of the patients were managed with supportive treatment with hydroxychloroquine and azithromycin given on a case-to-case basis. Only five (3.5%) patients required oxygen supplementation, four (2.8%) patients had severe disease requiring intensive care, one required mechanical ventilation and mortality occurred in two (1.4%) patients. The time to reverse transcription-polymerase chain reaction (RT-PCR) negativity was 16-18 days.
Interpretation & conclusions: : In this single-centre study of 144 hospitalized patients with confirmed COVID-19 in north India, the characteristic findings included younger age, high proportion of asymptomatic patients, long time to PCR negativity and low need for intensive care unit care.
Keywords: Clinico-epidemiologic - cough - COVID-19 - north India - outcome - prospective.