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India - Mystery fever mimicking dengue confounds doctors in Ahmedabad

Emily

Editor, Senior Moderator
http://timesofindia.indiatimes.com/city/ahmedabad/Mystery-fever-mimicking-dengue-confounds-doctors/articleshow/21947894.cms
Mystery fever mimicking dengue confounds doctors
TNN | Aug 21, 2013, 04.47 AM IST

AHMEDABAD: The sudden spurt in cases of a viral fever that is resistant to treatment has flummoxed doctors in the city. Children are its easy prey. Constant high fever, body ache and -in some cases - declining blood platelet count, have made it difficult for doctors to diagnose the causative virus. The common adage, "four days of rest for viral and then back to work", is now a concept of yesteryears.

Physicians across the city are encountering 30 to 40 such cases a day. Even municipal hospitals, like the VS Hospital in Paldi, are reporting 60 such cases every day...
 
Re: India - Mystery fever mimicking dengue confounds doctors in Ahmedabad

We've seen similar stories from around India in the past few years;


Mimic fever cases reported in Chandigarh
Kolkata: Unknown fever grips city, virus not identified
Unidentified dengue-like fever grips parts of Kolkata
Unidentified fevers in Punjab & Chandigarh

In one outbreak in Rajasthan, I think the mystery fever turned out to be scrub typhus. In general though, given the overall lack of a comprehensive surveillance system and huge underreporting of dengue & chikungunya in India, there is a very good chance that dengue and/or chikungunya are involved here. Chandigarh has officially reported 2 cases of Dengue and 0 cases of Chikungunya this year.
 
Re: India - Mystery fever mimicking dengue confounds doctors in Ahmedabad

ProMED comment on the first article;

The etiology of these cases has not been determined. Dengue is mentioned in the headline, but it is not clear if it has been ruled out by laboratory tests, nor if have any other of the many pathogens associated with febrile disease. The limited information provided does not permit reasonable speculation concerning which agents might be involved in these cases. An earlier series of cases of undiagnosed febrile disease were reported in Tamil Nadu state this year (2013) and in December 2012. ProMED-mail would appreciate receiving more details, and especially any additional laboratory results for the current outbreak, as they become available.

A HealthMap/ProMED-mail map showing the location of Gujarat state can be accessed at http://healthmap.org/r/27Ix. - Mod.TY
http://beta.promedmail.org/direct.php?id=20130822.1896201

Gujarat has reported 744 cases of Dengue with 1 fatality and 546 cases of Chikungunya to July 31st - Ro
 
Re: India - Mystery fever mimicking dengue confounds doctors in Ahmedabad

Thanks, Ronan. I'm glad ProMED is asking for more information. Maybe it's not the season and encephalopathy isn't mentioned in the Times article, but there was a follow-up to an article tetano posted about atypical H1N1 in India that mimicked dengue:

Pandemic H1N1 influenza with atypical presentation: Encephalopathy and severe thrombocytopenia
Our case had atypical presentation of H1N1 influenza with encephalopathy and severe thrombocytopenia. Because of such variable presentations of H1N1 virus, patients with viral fever, with or without flu-like symptoms, should be suspected and screened for H1N1 virus infection, especially in the presence of thrombocytopenia that could mimic dengue fever.
 
Re: India - Mystery fever mimicking dengue confounds doctors in Ahmedabad

Confirmation of Dengue in Ahmedabad;

Dengue bites eight students & two staffers of IIMA
Tuesday, Aug 27, 2013, 13:27 IST | Place: Ahmedabad | Agency: DNA
DNA Correspondent
Students advised against wearing shorts or sleeveless dresses on the campus


Indian Institute of Management, Ahmedabad (IIMA) has been stung by dengue again as eight students and two staff members were diagnosed with the disease till Monday.

A team of Ahmedabad Municipal Corporation (AMC) health officials visited the IIMA campus on Sunday to inspect the breeding of dengue-carrying Aedes Aegypti. Every year, IIMA faces the maximum threat of being a breeding ground for this particular variety Manoj Bhatt, chief administrative officer of IIMA, confirmed that eight students, mostly of first year Post Graduate Diploma Program in Management, and two staff members have been diagnosed with the disease.
...
http://www.dnaindia.com/ahmedabad/1...bites-eight-students-and-two-staffers-of-iima
 
Re: India - Mystery fever mimicking dengue confounds doctors in Ahmedabad

Unidentified virus on the prowl in Ahmedabad
Radha Sharma, TNN | Aug 31, 2013, 06.35 AM IST

AHMEDABAD: Doctors in the city are flooded with patients freaked out with high fever and excruciatingly painful joints all over the body. While the common refrain is that they have become victims of chikungunya, experts say that this might be a virus from the Arbovirus family which mimics chikungunya symptoms.

"We are seeing a number of patients who have symptoms similar to chikungunya, mainly high fever, severe joint and body pain but they test negative for chikungunya," says infectious diseases specialist Dr Atul Patel.
...
http://timesofindia.indiatimes.com/...e-prowl-in-Ahmedabad/articleshow/22177008.cms
 
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