Mary Wilson
Well-known member
ACCEPTED MANUSCRIPT
Bernd Jahrsd?rfer, Joris Kroschel, Carolin Ludwig, Victor Max Corman, Tatjana Schwarz, Sixten K?rper, Markus Rojewski, Ramin Lotfi, Christof Weinstock, Christian Drosten ... Show more
The Journal of Infectious Diseases, jiaa656, https://doi.org/10.1093/infdis/jiaa656
Published: 16 October 2020
Abstract
Highly sensitive and specific platforms for the detection of anti-SARS-CoV-2 antibodies are becoming increasingly important for (1) evaluating potential SARS-CoV-2 convalescent plasma donors, (2) studying the spread of SARS-CoV-2 infections and (3) identifying individuals with seroconversion. This study provides a comparative validation of four anti-SARS-CoV-2 platforms. Unique feature of this study is the use of a representative cohort of COVID-19-convalescent patients with mild-to-moderate disease course. All platforms showed significant correlations with a SARS-CoV-2 plaque-reduction-neutralization test, with highest sensitivities for the Euroimmun and the Roche platforms, suggesting their preferential use for screening of persons at increased risk of SARS-CoV-2 infections.
This content is only available as a PDF.
https://watermark.silverchair.com/j...B-5xW2T6CR0LMk8xvlIDvqu6pptRX_MINsznpbOyl0uUa
Bernd Jahrsd?rfer, Joris Kroschel, Carolin Ludwig, Victor Max Corman, Tatjana Schwarz, Sixten K?rper, Markus Rojewski, Ramin Lotfi, Christof Weinstock, Christian Drosten ... Show more
The Journal of Infectious Diseases, jiaa656, https://doi.org/10.1093/infdis/jiaa656
Published: 16 October 2020
Abstract
Highly sensitive and specific platforms for the detection of anti-SARS-CoV-2 antibodies are becoming increasingly important for (1) evaluating potential SARS-CoV-2 convalescent plasma donors, (2) studying the spread of SARS-CoV-2 infections and (3) identifying individuals with seroconversion. This study provides a comparative validation of four anti-SARS-CoV-2 platforms. Unique feature of this study is the use of a representative cohort of COVID-19-convalescent patients with mild-to-moderate disease course. All platforms showed significant correlations with a SARS-CoV-2 plaque-reduction-neutralization test, with highest sensitivities for the Euroimmun and the Roche platforms, suggesting their preferential use for screening of persons at increased risk of SARS-CoV-2 infections.
This content is only available as a PDF.
https://watermark.silverchair.com/j...B-5xW2T6CR0LMk8xvlIDvqu6pptRX_MINsznpbOyl0uUa