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Increased risk of non-influenza respiratory virus infections associated with receipt of inactivated influenza vaccine

tetano

Editor, Senior Moderator
Clin Infect Dis. 2012 Mar 15. [Epub ahead of print]
Increased risk of non-influenza respiratory virus infections associated with receipt of inactivated influenza vaccine.
Cowling BJ, Fang VJ, Nishiura H, Chan KH, Ng S, Ip DK, Chiu SS, Leung GM, Peiris JS.
Source

School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong Special Administrative Region, China.
Abstract

We randomized 115 children to trivalent inactivated influenza vaccine (TIV) or placebo. Over the following 9 months, TIV recipients had increased risk of virologically-confirmed non-influenza infections (relative risk: 4.40; 95% confidence interval: 1.31-14.8). Being protected against influenza, TIV recipients may lack temporary non-specific immunity that protected against other respiratory viruses.

PMID:
22423139
[PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/22423139
 
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