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Increase in respiratory illness reported in southeast Alabama: 10 hospitalizations, 2 deaths - multiple pathogens detected, including influenza A/H1N1

Re: Increase in respiratory illness reported in southeast Alabama (Health Dept., May 21 2013): 7 cases, 2 deaths -at least one case positive for H1N1

Re: Increase in respiratory illness reported in southeast Alabama (Health Dept., May 21 2013): 7 cases, 2 deaths -at least one case positive for H1N1

More details, read the whole article:

http://www.dothaneagle.com/news/article_c7cfba0a-c234-11e2-9bc6-0019bb30f31a.html

[snip]

Corey Kirkland, the assistant administrator for the area, said those two deaths occurred on Saturday and Sunday.

[snip]

Smith also said they don?t have a general common denominator among the seven people admitted to the hospital. She said they?ve had several young people and an elderly person among the cases, so it?s been difficult to determine who might specifically be at risk.
 
Re: Increase in respiratory illness reported in southeast Alabama (Health Dept., May 21 2013): 7 cases, 2 deaths -at least one case positive for H1N1

Re: Increase in respiratory illness reported in southeast Alabama (Health Dept., May 21 2013): 7 cases, 2 deaths -at least one case positive for H1N1

As I suspected by the wording above, a second positive:

http://www.wsfa.com/story/22313426/unknown-respiratory-illness-threatens-southeast-alabama

[snip]

The state health department says they are trying to find connections to these patients. So far, they have gathered that they are all adults ranging in age from early 20's to late 80s and they were all admitted into the Southeast Alabama Medical Center starting last Thursday.

Officials say one patient tested positive for the H1-NI flu virus and another person tested positive for Type A Flu. Right now health officials are treating the mystery illness like the flu.
 
Re: Increase in respiratory illness reported in southeast Alabama (Health Dept., May 21 2013): 7 cases, 2 deaths - one case positive for H1N1, another for unspecified influenza A

Re: Increase in respiratory illness reported in southeast Alabama (Health Dept., May 21 2013): 7 cases, 2 deaths - one case positive for H1N1, another for unspecified influenza A

[Source: Alabama Department of Health, full PDF document: (LINK). H / t HealthMap via Twitter.]


Alabama Department of Public Health ALERT Message 5/21/13


On 5/16/13, a pulmonologist in Southeast Alabama reported to the Alabama Department of Public Health (ADPH) that three patients had been hospitalized with cough, shortness of breath, and pneumonia, were on ventilators, and had no known cause for their illness. The ADPH and the Houston County Health Department began an epidemiology investigation to interview the families about travel and exposure.

Specimens were requested and submitted to the ADPH Bureau of Clinical Laboratories (BCL) in Montgomery.

On 5/17/13, BCL reported one of the three patients tested positive for 2009 H1N1. On 5/18/13, this patient died. On 5/19/13, the same hospital reported that a transferred patient on a ventilator with respiratory symptoms had died. On 5/19/13, this hospital had nine additional patients present to the emergency department with influenza-like illness and three of those patients were admitted. Specimens have been collected on all patients. The BCL has tested all specimens on a PCR flu panel and one tested positive for AH3. The specimens were also forwarded to CDC for additional testing.

At this time, there is no epidemiological link between these patients. While two patients have tested positive for influenza, the exact role of influenza in this cluster is unknown. On 5/21/13, ADPH sent a News Release regarding the situation.

ADPH has reiterated that healthcare providers should use standard precautions when dealing with patients with respiratory illness. Physicians should use clinical judgment in determining the best treatment for their patients since the etiology of the outbreak is unknown at this time.


REPORTING

Please report all patients currently hospitalized with pneumonia, with unknown cause (regardless of quick flu test results), to www.adph.org/epi, Respiratory Illness REPORT Card.


SPECIMEN COLLECTION

For patients who present with fever (>100.4F) and cough or shortness of breath with unknown cause (regardless of quick flu test results), please submit an upper tract specimen, ie, oropharyngeal (OP) swab or nasopharyngeal (NP) swab, to the Bureau of Clinical Laboratories as part of ADPH's year-round influenza surveillance program. For more information about collecting, packing, and submitting lab specimens, please go to http://adph.org/bcl/assets/Guide_Lab_Test_Inf_Virus_092210.pdf or call BCL 334-260-3429, Microbiology Division.

For patients who present with pneumonia with unknown cause (regardless of quick flu test results), please collect and submit a lower tract specimen, ie, bronchoalveolar lavage, tracheal aspirate, or sputum, to the BCL.

For patients admitted to the hospital with cough or shortness of breath, and pneumonia (regardless of quick flu test results), with unknown cause, please send both upper and lower tract specimens. Multiple respiratory specimen types with ample volume are preferred.

If you have any questions, please contact the Epidemiology Division at 1-800-338-8374 and ask to speak with staff involved in the Respiratory Illness Outbreak.


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Re: Increase in respiratory illness reported in southeast Alabama (Health Dept., May 21 2013): 7 cases, 2 deaths - one fatal case positive for influenza A/H1N1, another for influenza A/H3

Re: Increase in respiratory illness reported in southeast Alabama (Health Dept., May 21 2013): 7 cases, 2 deaths - one fatal case positive for influenza A/H1N1, another for influenza A/H3

That is an excellent summary.

So the patient who tested positive for H1N1 has died on May 18. One additional patient (no test results) died on May 19. One surviving patient admitted later has tested positive for (presumably seasonal) H3. So the 7 patients hospitalized consist of the original 3 (1 dead), the extra death on May 19, and the three later admissions (all alive).

It also indicates that other cases have reported to the ER, but not been admitted. Perhaps not surprising, because comments on some of the other articles have indicates an overall increase in ARI in the area.
 
Re: Increase in respiratory illness reported in southeast Alabama (Health Dept., May 21 2013): 7 hospitalizations, 2 deaths - one fatal case positive for influenza A/H1N1, one hospitalized case for influenza A/H3

Re: Increase in respiratory illness reported in southeast Alabama (Health Dept., May 21 2013): 7 hospitalizations, 2 deaths - one fatal case positive for influenza A/H1N1, one hospitalized case for influenza A/H3

http://www.troymessenger.com/2013/05/21/mystery-illness-hospitalizes-seven-kills-two-in-southeast-alabama/
Mystery illness hospitalizes seven, kills two in southeast Alabama
Published 11:00pm Tuesday, May 21, 2013
By Stacy Graning
[snip]
Dr. Mary McIntyre, an assistant sate health officer for disease control and prevention with the Alabama Department of Public Health, said Tuesday the seven reported cases are all linked to one hospital in Dothan...
 
Re: Increase in respiratory illness reported in southeast Alabama (Health Dept., May 21 2013): 7 hospitalizations, 2 deaths - one fatal case positive for influenza A/H1N1, one hospitalized case for influenza A/H3

Re: Increase in respiratory illness reported in southeast Alabama (Health Dept., May 21 2013): 7 hospitalizations, 2 deaths - one fatal case positive for influenza A/H1N1, one hospitalized case for influenza A/H3

Source Alabama Department of Health: http://www.adph.org/

Respiratory Illness Outbreak - Information for healthcare providers who need to submit a hospitalized patient with pneumonia and unknown cause, as well as other information, is on our Epidemiology Division Website (http://www.adph.org/epi ).
 
Re: Increase in respiratory illness reported in southeast Alabama (Health Dept., May 21 2013): 7 hospitalizations, 2 deaths - one fatal case positive for influenza A/H1N1, one hospitalized case for influenza A/H3

Re: Increase in respiratory illness reported in southeast Alabama (Health Dept., May 21 2013): 7 hospitalizations, 2 deaths - one fatal case positive for influenza A/H1N1, one hospitalized case for influenza A/H3

Multiple causes suspected?

http://tbo.com/health/cdc-chases-ca...ala-ap_health75b7cefe03d146949ff8ae8d627427bb

CDC chases cause of mystery illness in SE Ala.
Published: May 22, 2013
MONTGOMERY, Ala. (AP) ? Doctors throughout Alabama have gotten notices from the State Department of Health about the unidentified respiratory illness that has killed two and hospitalized five more.

The Centers for Disease Control and the Alabama State Department of Health were investigating a cluster of hospital admissions Wednesday of people that have recently been admitted with flu-like symptoms in southeastern Alabama. Three remain hospitalized and two have been released.

Dr. Mary McIntyre of the Alabama Department of Public Health said that all of the severe illnesses were accompanied by pneumonia and may have had more than one contributing factor. McIntyre says the two people that died had different, but relatively common, forms of influenza.

Further information from the CDC is expected on Thursday morning. McIntyre says obesity can complicate serious respiratory illnesses.
 
Re: Increase in respiratory illness reported in southeast Alabama (Health Dept., May 21 2013): 7 hospitalizations, 2 deaths - one fatal case positive for influenza A/H1N1, one hospitalized case for influenza A/H3

Re: Increase in respiratory illness reported in southeast Alabama (Health Dept., May 21 2013): 7 hospitalizations, 2 deaths - one fatal case positive for influenza A/H1N1, one hospitalized case for influenza A/H3

CDC continues search for Ala. mystery illness cause

<NOSCRIPT></NOSCRIPT><!--END wnDate-->Updated: May 22, 2013 3:13 PM CDT<NOSCRIPT></NOSCRIPT><!--END wnDate-->
By Tametria Conner -
By John Shryock -

Alabama Department of Public Health spokeswoman Dr. Mary McIntyre says those admitted for treatment suffered from fever, cough and shortness of breath. She says all of the severe illnesses were accompanied by pneumonia and may have had more than one contributing factor,

"We are running a multiple panel test that actually looks for viruses and bacteria so we can try to make sure we're not dealing with anything unusual," Dr. McIntyre said. Further information from the CDC is expected on Thursday morning.

Dr. McIntyre says the two people who died had different, but relatively common, forms of influenza.

Public health officials say they really don't know what they are dealing with and they have no idea if it has spread to other areas. That's why they are in constant contact with the Centers for Disease control, hoping the CDC can figure it out. The CCDC and ADPH are currently investigating the string of illnesses.
...

Full text:
http://www.wsfa.com/story/22313426/mystery-illness-kills-2-alabama-residents-hospitalizes-5-others
 
Re: Increase in respiratory illness reported in southeast Alabama (Health Dept., May 21 2013): 9 hospitalizations, 2 deaths - one fatal case positive for influenza A/H1N1, one hospitalized case for influenza A/H3

Re: Increase in respiratory illness reported in southeast Alabama (Health Dept., May 21 2013): 9 hospitalizations, 2 deaths - one fatal case positive for influenza A/H1N1, one hospitalized case for influenza A/H3

One illness fatality linked to H1N1 flu virus
Total cases increased to 9

Posted: Wednesday, May 22, 2013 3:44 pm | Updated: 4:54 pm, Wed May 22, 2013.
by Matt Elofson

Officials with the local office of the state Department of Public Health said Wednesday that one of the two deaths that are part of a recent respiratory illness outbreak could be associated with the H1N1 flu virus.

Lesa C. Smith, a registered nurse with state Department of Public Health, also said the number of people admitted to local hospitals during the recent respiratory illness outbreak has increased from seven to nine.

?We can?t say that the person died with H1N1, but we can say it was a death associated with it,? Smith said. ?A total of nine have been admitted. We know some people are recovering, and are going home.?
...
?We?re still in the investigative state, and we?re still waiting other tests to come back,? Kirkland said.

Health department officials have said all nine people admitted to local hospitals were within an eight-county southeast region, which includes Barbour, Coffee, Crenshaw, Dale, Geneva, Henry, Houston and Pike County.
...
http://www.dothaneagle.com/news/article_7a18c9cc-c320-11e2-a2d5-0019bb30f31a.html
 
Re: Increase in respiratory illness reported in southeast Alabama (Health Dept., May 21 2013): 7 hospitalizations, 2 deaths - one fatal case positive for influenza A/H1N1, one hospitalized case for influenza A/H3

Re: Increase in respiratory illness reported in southeast Alabama (Health Dept., May 21 2013): 7 hospitalizations, 2 deaths - one fatal case positive for influenza A/H1N1, one hospitalized case for influenza A/H3

Ala. mystery illness cases climb to 10; CDC still investigating

Posted: May 21, 2013 12:05 PM CDT Updated: May 22, 2013 5:09 PM CDT
By Tametria Conner -
By John Shryock -

HOUSTON CO., AL (WSFA) -

The number of mystery illness cases affecting Alabama is growing.
Wednesday, Alabama Department of Public Health spokeswoman Dr. Mary McIntyre confirmed the number rose to ten overnight from a previous report of seven. Two people have died.

"Since we sent out the alert to providers last night, we have had three additional patients/cases," Dr. McIntyre told WSFA 12 News. "These patients all have the same symptoms of cough, shortness of breath and "something" on their chest x-rays," she explained.

Dr. McIntyre says it wasn't immediately known if all the new cases were in southeast Alabama, like the previous seven. But she said at least one person was admitted to Southeast Alabama Medical Center in the last 24 hours.

"We have staff right now in the field trying to get additional information about the other two patients," McIntyre said. No additional information on the three new cases is immediately available.

More...
http://www.wsfa.com/story/22313426/...-of-alabama-mystery-illness-cases-climb-to-10
 
Re: Discussion: Alabama respiratory illnesses

Re: Discussion: Alabama respiratory illnesses

http://www.wtvy.com/home/headlines/Update-in-Mystery-Illness-Deaths-Expected-Thursday-208548201.html
Posted: Wed 3:44 PM, May 22, 2013
Reporter: Associated Press
Updated: Wed 6:53 PM, May 22, 2013
Update in Mystery Illness Deaths Expected Thursday
[snip]
Further information from the CDC is expected on Thursday morning. McIntyre says obesity can complicate serious respiratory illnesses.
 
Re: Increase in respiratory illness reported in southeast Alabama (Health Dept., May 21 2013): 7 hospitalizations, 2 deaths - one fatal case positive for influenza A/H1N1, one hospitalized case for influenza A/H3

Re: Increase in respiratory illness reported in southeast Alabama (Health Dept., May 21 2013): 7 hospitalizations, 2 deaths - one fatal case positive for influenza A/H1N1, one hospitalized case for influenza A/H3

http://abcnews.go.com/Health/alabama-mystery-illness-coincidence/story?id=19236893

Alabama Mystery Illness Could Be Coincidence

A mystery illness has sickened seven people in southeastern Alabama, killing two of them, according to the state Health Department, but it's not clear whether the patients ? or their symptoms ? are connected.

"At this time, there is no epidemiological link between these patients," an Alabama health department document states in bold type.

The patients' ages range from their mid-20s to their late 80s, Dr. Mary McIntyre, who is leading the investigation, told ABCNews.com in an email. Location aside, McIntyre said the patients had no commonalities other than that the "majority" of them had "co-morbidities like smoking, COPD, morbid obesity."

"Temporal clustering can make something look like an outbreak," said Dr. Richard Besser, chief health and medical editor for ABC News. "Good science will tell you whether it is."

[snip]
 
Re: Increase in respiratory illness reported in southeast Alabama (Health Dept., May 21 2013): 7 hospitalizations, 2 deaths - one fatal case positive for influenza A/H1N1, one hospitalized case for influenza A/H3

Re: Increase in respiratory illness reported in southeast Alabama (Health Dept., May 21 2013): 7 hospitalizations, 2 deaths - one fatal case positive for influenza A/H1N1, one hospitalized case for influenza A/H3

This suggests that the two confirmed cases are actually both the fatal ones:

http://www.myfoxal.com/story/223134...-of-alabama-mystery-illness-cases-climb-to-10

[snip]

Dr. McIntyre says the two people who died had different, but relatively common, forms of influenza.
 
Re: Increase in respiratory illness reported in southeast Alabama (Health Dept., May 21 2013): 7 hospitalizations, 2 deaths - one fatal case positive for influenza A/H1N1, one hospitalized case for influenza A/H3

Re: Increase in respiratory illness reported in southeast Alabama (Health Dept., May 21 2013): 7 hospitalizations, 2 deaths - one fatal case positive for influenza A/H1N1, one hospitalized case for influenza A/H3

Is this a reporting error, or has there been a third influenza positive?

http://www.chicagotribune.com/health/sns-rt-us-usa-alabama-illnessbre94l18r-20130522,0,463341.story

BIRMINGHAM, Alabama (Reuters) - U.S. and state health authorities are investigating an unidentified respiratory illness that has killed two of 10 people hospitalized with it in Alabama since last week.

Preliminary tests do not indicate the bird flu, nor a new mutation of any known influenza virus, said Dr. Mary McIntyre, an assistant state health officer at the Alabama Department of Public Health. Two patients did test positive for the H1N1 strain of the flu.

Bacteria such as MRSA (Methicillin-resistant Staphylococcus Aureus) remains a possibility, especially as a secondary infection, McIntyre said on Wednesday. However, one patient tested for MRSA by a physician had negative results.

"At this point, it could be anything. We are testing for everything," McIntyre said.

State health officials believe it is unlikely the patients are suffering from the new coronavirus that surfaced in the Middle East last year, because none had traveled, she said.

Laboratory samples were sent to the Centers for Disease Control and Prevention in Atlanta for evaluation, and the agency is expected to issue a report within 24 hours, she said.

[snip]

------------

[The reports are not consistent on who has tested positive for which virus. We know one person has tested positive for H1N1 and died. Another person has tested positive for (seasonal?) H3. Some reports indicate this person is the other fatality; others indicate they are still hospitalized, and the other fatal case is undiagnosed.

Now this article suggests two confirmed H1N1 cases, meaning the second one is still alive (as if both fatalities were confirmed H1N1, the article would say that). So it is possible that three cases have been confirmed due to influenza, inclduing at least one, if not both, deaths.

I also have to question the wording of this article. How can they know the influenza virus has not "mutated" if they have not sequenced it yet?] - alert
 
Re: Increase in respiratory illness reported in southeast Alabama: 10 hospitalizations, 2 deaths - one fatal case positive for influenza A/H1N1, one hospitalized case for influenza A/H3

Re: Increase in respiratory illness reported in southeast Alabama: 10 hospitalizations, 2 deaths - one fatal case positive for influenza A/H1N1, one hospitalized case for influenza A/H3

News Conference Today at 1 PM Central Time
 
Re: Increase in respiratory illness reported in southeast Alabama: 10 hospitalizations, 2 deaths - one fatal case positive for influenza A/H1N1, one hospitalized case for influenza A/H3

Re: Increase in respiratory illness reported in southeast Alabama: 10 hospitalizations, 2 deaths - one fatal case positive for influenza A/H1N1, one hospitalized case for influenza A/H3

Looks like multiple causes. It would be nice to know what, besides influenza, has been detected. Adenovirus? Rhinovirus? RSV?

http://www.sfgate.com/news/article/Tests-No-common-germ-behind-illness-cluster-4543057.php

Tests: No common germ behind illness cluster

By MIKE STOBBE, AP Medical Writer
Published 10:22 am, Thursday, May 23, 2013

Officials investigating a cluster of mysterious illnesses in Alabama have so far found only cold and flu viruses.

In tests on seven of the nine patients, the Centers for Disease Control and Prevention found no sign that the illnesses were caused by any single germ, CDC spokeswoman Sharon Hoskins said in an email.

Meanwhile, Alabama officials said they had added two more cases to the cluster, which included two earlier deaths.

Seven of the cases were reported last week, including the deaths. The two new illnesses were reported this week.

Most of the nine were treated at Southeast Alabama Medical Center in Dothan, but one was seen at a hospital in Crenshaw County.

[snip]
 
Re: Increase in respiratory illness reported in southeast Alabama: 10 hospitalizations, 2 deaths - one fatal case positive for influenza A/H1N1, one hospitalized case for influenza A/H3

Re: Increase in respiratory illness reported in southeast Alabama: 10 hospitalizations, 2 deaths - one fatal case positive for influenza A/H1N1, one hospitalized case for influenza A/H3

Press Conference indicates rhinoviruses, associated "typical" bacterial co-infections and a few cases of influenza.

Nothing strikingly unusual per the Alabama Health Department.

Phew. :)
 
Re: Increase in respiratory illness reported in southeast Alabama: 10 hospitalizations, 2 deaths - one fatal case positive for influenza A/H1N1, one hospitalized case for influenza A/H3

Re: Increase in respiratory illness reported in southeast Alabama: 10 hospitalizations, 2 deaths - one fatal case positive for influenza A/H1N1, one hospitalized case for influenza A/H3

Also from the press conference:

http://www.wsfa.com/category/256641/wsfa-12-news-live-streaming-online

Of the original 7 patients:

3 total influenza A positives (presumably 2 H1N1 and 1 H3)
4 total rhinovirus positives
3 total bacterial co-infections detected

Obviously, some of the patients have tested positive for more than one agent.
 
Re: Increase in respiratory illness reported in southeast Alabama: 10 hospitalizations, 2 deaths - multiple pathogens detected, including influenza A/H1N1, influenza A/H3, and rhinovirus

Thanks curiosity and alert for your notes. :)

also my notes:

#USA - #Alabama -News conf. about #respiratory illness cluster at 1pm central time http://www.adph.org/ALPHTN/index.asp?id=5073 … @Fla_Medic h/t curiosity #flu #fb

News conference starting.... 7 patients test negative for #nCoV and #coronavirus #Alabama #USA

3 patients test + #flu :A/H3 seasonal, H1N1pdm09,1 untyped &4 have rhinovirus- 3 patients also infected w/"normal"bacteria #Alabama #USA

7 Patients age range from 32-87. Deaths in patients aged 34 & 55. #Alabama #USA

Tests pending on additional 3 patients for a total of 10 hospitalized #Alabama #USA

General pneumonia is not reportable in #Alabama unless medical personnel suspect unusual situation #USA

Dr. Williamson is the person giving the news update for the state of #Alabama #USA

Total of 10 patients:3 w/flu A,4 w/rhinovirus-3 w/common bacteria in addition:Age CORRECTION range:24- 87 for all 10 patients #Alabama #USA

#Alabama state news conference for respiratory illness outbreak is concluded #USA
 
Last edited:
Re: Increase in respiratory illness reported in southeast Alabama: 10 hospitalizations, 2 deaths - multiple pathogens detected, including influenza A/H1N1, influenza A/H3, and rhinovirus

[Source: Alabama Department of Health, full PDF document: (LINK). Edited.]


NEWS RELEASE

ALABAMA DEPARTMENT OF PUBLIC HEALTH, RSA Tower 201 Monroe Street, Suite 914 Montgomery, AL 36104, Phone 334-206-5300 Fax 334-206-5534, www.adph.org

Cause of respiratory illness cluster in southeast Alabama determined

FOR IMMEDIATE RELEASE

CONTACT: Mary McIntyre, M.D., M.P.H., (334) 206-5971, Corey Kirkland, (334) 792-9070


The Alabama Department of Public Health (ADPH) and the Houston County Health Department have determined that the cause of a respiratory illness cluster in southeast Alabama was a combination of influenza A, rhinovirus, the virus associated with the common cold, and bacterial pneumonia.

?This is good news. Testing has ruled out avian flu and novel coronavirus,? said State Health Officer Dr. Don Williamson.

Earlier this month, seven patients were admitted to the hospital with fever, cough and shortness of breath with no known cause for their illness. Public health officials began an epidemiological investigation to interview the families of the patients about travel and exposure.

Specimens were requested and submitted to the ADPH Bureau of Clinical Laboratories in Montgomery.

Of the seven patients whose specimens were submitted, six were found to be positive for either influenza A, rhinovirus or a combination of the two, and three patients were found to have bacterial pneumonia. Two of the seven patients eventually died.

Dr. Mary McIntyre, assistant state health officer for disease control and prevention, said, ?While enhanced surveillance associated with this cluster is no longer necessary, health care providers are encouraged to continue routine year-round influenza surveillance activities and submit specimens to the state laboratory for testing.?

Health care providers should always use standard precautions when dealing with patients with respiratory illness.

If you or your family members have respiratory symptoms of fever, cough and shortness of breath, please contact your health care provider to be evaluated.

In addition, everyone should take steps to prevent transmission of disease and are reminded to follow these precautions:
  • Cover your cough or sneeze with a sleeve or tissue.
  • Wash your hands often with soap and water, especially after you cough or sneeze. Alcoholbased hand sanitizers are also effective.
  • Avoid touching your mouth, eyes and nose with your hands. Try to avoid close contact with sick people.
  • If you get sick, stay home and limit contact with others to avoid infecting them.
-30- 5/23/13


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