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Impact of Late Oseltamivir Treatment on Influenza Symptoms in the Outpatient Setting: Results of a Randomized Trial

tetano

Editor, Senior Moderator
Open Forum Infect Dis. 2015 Jul 8;2(3):ofv100. doi: 10.1093/ofid/ofv100. eCollection 2015.
[h=1]Impact of Late Oseltamivir Treatment on Influenza Symptoms in the Outpatient Setting: Results of a Randomized Trial.[/h] McLean HQ[SUP]1[/SUP], Belongia EA[SUP]1[/SUP], Kieke BA[SUP]1[/SUP], Meece JK[SUP]2[/SUP], Fry AM[SUP]3[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] We conducted a double-blind, randomized trial of 134 outpatients with polymerase chain reaction-confirmed influenza to assess the effects of oseltamivir initiated 48-119 hours after illness onset. Oseltamivir treatment did not reduce illness duration, severity, or duration of virus detection. However, the power of this study was limited due to lower than expected enrollment.


[h=4]KEYWORDS:[/h] influenza; oseltamivir

PMID: 26258157 [PubMed]
 
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