tetano
Editor, Senior Moderator
Diagn Microbiol Infect Dis. 2018 Apr 4. pii: S0732-8893(18)30103-2. doi: 10.1016/j.diagmicrobio.2018.03.013. [Epub ahead of print]
[h=1]Impact of a multiplex PCR point-of-care test for influenza A/B and respiratory syncytial virus on an acute pediatric hospital ward.[/h] Vecino-Ortiz AI[SUP]1[/SUP], Goldenberg SD[SUP]2[/SUP], Douthwaite ST[SUP]2[/SUP], Cheng CY[SUP]3[/SUP], Glover RE[SUP]3[/SUP], Mak C[SUP]3[/SUP], Adams EJ[SUP]4[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Patients with respiratory infections are often managed presumptively until confirmation of infection status. We assessed the impact of introducing the Enigma? MiniLab? FluAB-RSV point-of-care test (POCT) on patients admitted with a suspected respiratory virus driven illness in an acute pediatric ward. This utilized a before and after design (respiratory viral seasons 2013/14 versus 2014/15). Following POCT implementation, oseltamivir prescribing increased in patients with influenza (OR = 12.7, P = 0.05, 95% CI [1.0, 153.8]). A reduction in the average reimbursement charges without a change in the length of stay was observed. Modeling suggested that laboratory test cost savings could be achieved if the POCT cost ?30 and was used for screening, followed by the respiratory viral panel for RSV and influenza negative patients. A rapid POCT for influenza A/B and RSV infections in pediatric inpatients may improve oseltamivir prescribing, strengthen antimicrobial stewardship, reduce reimbursement charges and decrease laboratory costs.
[h=4]KEYWORDS:[/h] Influenza virus A; Influenza virus B; Point-of-care technology; Rapid diagnostic tests; Respiratory syncytial virus
PMID: 29706478 DOI: 10.1016/j.diagmicrobio.2018.03.013
[h=1]Impact of a multiplex PCR point-of-care test for influenza A/B and respiratory syncytial virus on an acute pediatric hospital ward.[/h] Vecino-Ortiz AI[SUP]1[/SUP], Goldenberg SD[SUP]2[/SUP], Douthwaite ST[SUP]2[/SUP], Cheng CY[SUP]3[/SUP], Glover RE[SUP]3[/SUP], Mak C[SUP]3[/SUP], Adams EJ[SUP]4[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Patients with respiratory infections are often managed presumptively until confirmation of infection status. We assessed the impact of introducing the Enigma? MiniLab? FluAB-RSV point-of-care test (POCT) on patients admitted with a suspected respiratory virus driven illness in an acute pediatric ward. This utilized a before and after design (respiratory viral seasons 2013/14 versus 2014/15). Following POCT implementation, oseltamivir prescribing increased in patients with influenza (OR = 12.7, P = 0.05, 95% CI [1.0, 153.8]). A reduction in the average reimbursement charges without a change in the length of stay was observed. Modeling suggested that laboratory test cost savings could be achieved if the POCT cost ?30 and was used for screening, followed by the respiratory viral panel for RSV and influenza negative patients. A rapid POCT for influenza A/B and RSV infections in pediatric inpatients may improve oseltamivir prescribing, strengthen antimicrobial stewardship, reduce reimbursement charges and decrease laboratory costs.
[h=4]KEYWORDS:[/h] Influenza virus A; Influenza virus B; Point-of-care technology; Rapid diagnostic tests; Respiratory syncytial virus
PMID: 29706478 DOI: 10.1016/j.diagmicrobio.2018.03.013