tetano
Editor, Senior Moderator
Clin Vaccine Immunol. 2012 Aug 1. [Epub ahead of print]
Immunogenicity of a Monovalent A/H1pdm Vaccine with or without prior Seasonal Influenza Vaccine Administration.
Igari H, Watanabe A, Segawa S, Suzuki A, Watanabe M, Sakurai T, Watanabe M, Tatsumi K, Nakayama M, Suzuki K, Sato T.
Source
Divisions of Control and Treatment of Infectious Diseases.
Abstract
The immunogenicity of A/H1pdm vaccine might be modified by prior seasonal trivalent influenza vaccine (sTIV). We conducted a retrospective analysis of immunogenicity of 243 health-care workers (sTIV+:216, sTIV-:27) by hemagglutination-inhibition. There was no significant difference in the ratio of antibody titers of >=40 (41.2% versus 48.1%; P=0.49) and factor increase in geometric mean titer (3.8 versus 4.5; P=0.37). sTIV injected 7-10 days prior to A/H1pdm vaccine did not interfere with the immunogenicity of the latter.
PMID:
22855394
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/22855394
Immunogenicity of a Monovalent A/H1pdm Vaccine with or without prior Seasonal Influenza Vaccine Administration.
Igari H, Watanabe A, Segawa S, Suzuki A, Watanabe M, Sakurai T, Watanabe M, Tatsumi K, Nakayama M, Suzuki K, Sato T.
Source
Divisions of Control and Treatment of Infectious Diseases.
Abstract
The immunogenicity of A/H1pdm vaccine might be modified by prior seasonal trivalent influenza vaccine (sTIV). We conducted a retrospective analysis of immunogenicity of 243 health-care workers (sTIV+:216, sTIV-:27) by hemagglutination-inhibition. There was no significant difference in the ratio of antibody titers of >=40 (41.2% versus 48.1%; P=0.49) and factor increase in geometric mean titer (3.8 versus 4.5; P=0.37). sTIV injected 7-10 days prior to A/H1pdm vaccine did not interfere with the immunogenicity of the latter.
PMID:
22855394
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/22855394