tetano
Editor, Senior Moderator
Vaccine. 2011 Feb 21. [Epub ahead of print]
Immune response to influenza A (H1N1) monovalent MF59-adjuvanted vaccine in HIV-infected patients.
Fabbiani M, Di Giambenedetto S, Sali M, Farina S, Sansonetti P, Tamburrini E, Verme LZ, Delogu G, De Luca A, Kelvin D, Cauda R, Fadda G.
Institute of Clinical Infectious Diseases, Catholic University of Sacred Heart, Largo F. Vito 1, 00168 Rome, Italy.
Abstract
Immunogenicity of influenza A (H1N1)v MF59-adjuvanted vaccine was studied in HIV-infected patients. The vaccine was effective in inducing a protective immune response in patients with a CD4 >200cells/μL while individuals with CD4 <200cells/μL showed lower rates of seroconversion and seroprotection. These results underscore the usefulness of immunization against influenza in HIV-infected patients, though a boosting dose of vaccine may be required in seriously immunocompromised patients.
Copyright ? 2011. Published by Elsevier Ltd.
PMID: 21349364 [PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/21349364
Immune response to influenza A (H1N1) monovalent MF59-adjuvanted vaccine in HIV-infected patients.
Fabbiani M, Di Giambenedetto S, Sali M, Farina S, Sansonetti P, Tamburrini E, Verme LZ, Delogu G, De Luca A, Kelvin D, Cauda R, Fadda G.
Institute of Clinical Infectious Diseases, Catholic University of Sacred Heart, Largo F. Vito 1, 00168 Rome, Italy.
Abstract
Immunogenicity of influenza A (H1N1)v MF59-adjuvanted vaccine was studied in HIV-infected patients. The vaccine was effective in inducing a protective immune response in patients with a CD4 >200cells/μL while individuals with CD4 <200cells/μL showed lower rates of seroconversion and seroprotection. These results underscore the usefulness of immunization against influenza in HIV-infected patients, though a boosting dose of vaccine may be required in seriously immunocompromised patients.
Copyright ? 2011. Published by Elsevier Ltd.
PMID: 21349364 [PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/21349364