tetano
Editor, Senior Moderator
Immun Inflamm Dis
. 2021 Sep 9.
doi: 10.1002/iid3.525. Online ahead of print.
SARS-CoV-2 infection shortly after BNT162b2 vaccination results in high anti-spike antibody levels in nursing home residents and staff
Doris Urlaub[SUP] 1 [/SUP], Natalie Wolfsdorff[SUP] 1 [/SUP], Deniz Durak[SUP] 2 [/SUP], Frank Renken[SUP] 2 [/SUP], Carsten Watzl[SUP] 1 [/SUP]
Affiliations
Abstract
Introduction: One dose of a coronavirus disease 2019 (COVID-19) vaccine can elicit high antibody titers in individuals who were previously infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, it is unclear how a SARS-CoV-2 infection shortly after a first COVID-19 vaccine dose affects antibody responses.
Methods: Here we investigate residents and staff of a nursing home, where a COVID-19 outbreak occurred shortly after the first BNT162b2 immunization.
Results and conclusions: Our data show that individuals who got infected as early as 10 days after their first immunization show antibody levels comparable to fully vaccinated individuals.
Keywords: COVID-19; SARS-CoV-2; anti-SARS-CoV-2 spike antibodies; vaccine.
. 2021 Sep 9.
doi: 10.1002/iid3.525. Online ahead of print.
SARS-CoV-2 infection shortly after BNT162b2 vaccination results in high anti-spike antibody levels in nursing home residents and staff
Doris Urlaub[SUP] 1 [/SUP], Natalie Wolfsdorff[SUP] 1 [/SUP], Deniz Durak[SUP] 2 [/SUP], Frank Renken[SUP] 2 [/SUP], Carsten Watzl[SUP] 1 [/SUP]
Affiliations
- PMID: 34499821
- DOI: 10.1002/iid3.525
Abstract
Introduction: One dose of a coronavirus disease 2019 (COVID-19) vaccine can elicit high antibody titers in individuals who were previously infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, it is unclear how a SARS-CoV-2 infection shortly after a first COVID-19 vaccine dose affects antibody responses.
Methods: Here we investigate residents and staff of a nursing home, where a COVID-19 outbreak occurred shortly after the first BNT162b2 immunization.
Results and conclusions: Our data show that individuals who got infected as early as 10 days after their first immunization show antibody levels comparable to fully vaccinated individuals.
Keywords: COVID-19; SARS-CoV-2; anti-SARS-CoV-2 spike antibodies; vaccine.