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IgA nephropathy presenting as macroscopic hematuria in 2 pediatric patients after receiving the Pfizer COVID-19 vaccine

Emily

Editor, Senior Moderator
Christian Hanna, Loren P. Herrera Hernandez, Lihong Bu, Sarah Kizilbash, Lydia Najera, Michelle N. Rheault, Jan Czyzyk, Anne M. Kouri,
IgA nephropathy presenting as macroscopic hematuria in 2 pediatric patients after receiving the Pfizer COVID-19 vaccine,
Kidney International,
Volume 100, Issue 3,
2021,
Pages 705-706,
ISSN 0085-2538,
https://doi.org/10.1016/j.kint.2021.06.032.
(https://www.sciencedirect.com/science/article/pii/S0085253821006669)

To the editor:

With great interest, we read the recent reports of IgA nephropathy (IgAN) flare-up presenting as macroscopic hematuria, following the second dose of coronavirus disease 2019 (COVID-19) vaccination in adult patients.1, 2, 3, 4 The US Food and Drug Administration granted an emergency use authorization for the Pfizer–BioNtech COVID-19 vaccination in December 2020 for individuals aged ≥16 years; the emergency use authorization was recently expanded to include children aged 12 to 15 years on May 10, 2021. Herein, we report 2 pediatric patients with IgAN presenting with macroscopic hematuria <24 hours after Pfizer COVID-19 vaccination. Neither patient had COVID-19 infection before vaccination nor any history of reactions to any vaccinations. See Table 1 for clinical information.
 
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