tetano
Editor, Senior Moderator
J Mol Biol. 2013 Sep 25. pii: S0022-2836(13)00608-6. doi: 10.1016/j.jmb.2013.09.024. [Epub ahead of print]
IFITMs restrict the replication of multiple pathogenic viruses.
Perreira JM, Chin CR, Feeley EM, Brass AL.
Source
Microbiology and Physiological Systems (MaPS) Department, University of Massachusetts Medical School, Albert Sherman Center 8 1001, 368 Plantation St., Worcester, MA 01655, USA.
Abstract
The IFITM family of proteins inhibit a growing number of pathogenic viruses, among them influenza A virus, dengue virus, hepatitis C virus, and Ebola virus. This review covers recent developments in our understanding of the IFITM's molecular determinants, potential mechanisms of action, and impact on pathogenesis.
? 2013.
KEYWORDS:
CD225 family, IFITM, host virus interactions, interferon effector genes, restriction factor
PMID:
24076421
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/24076421
IFITMs restrict the replication of multiple pathogenic viruses.
Perreira JM, Chin CR, Feeley EM, Brass AL.
Source
Microbiology and Physiological Systems (MaPS) Department, University of Massachusetts Medical School, Albert Sherman Center 8 1001, 368 Plantation St., Worcester, MA 01655, USA.
Abstract
The IFITM family of proteins inhibit a growing number of pathogenic viruses, among them influenza A virus, dengue virus, hepatitis C virus, and Ebola virus. This review covers recent developments in our understanding of the IFITM's molecular determinants, potential mechanisms of action, and impact on pathogenesis.
? 2013.
KEYWORDS:
CD225 family, IFITM, host virus interactions, interferon effector genes, restriction factor
PMID:
24076421
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/24076421