tetano
Editor, Senior Moderator
IDCases
. 2020 May 22;21:e00819.
doi: 10.1016/j.idcr.2020.e00819. eCollection 2020.
Oseltamivir and Baloxavir: Dual Treatment for Rapidly Developing ARDS on a Patient With Renal Disease
Pool Tobar Vega[SUP] 1 [/SUP], Elena Caldeira[SUP] 1 [/SUP], Hasan Abad[SUP] 1 [/SUP], Peguy Saad[SUP] 1 [/SUP], Erik Lachance[SUP] 1 [/SUP]
Affiliations
Abstract
Influenza is an annual epidemic disease that in severe cases can lead to the development of ARDS. Current practice recommends the routine use of neuraminidase inhibitors with emerging evidence for the use of endonuclease inhibitors. We present the case of a 22-year-old female with diabetes and IgG4 tubulo-interstitial nephritis that developed rapidly progressive ARDS from influenza infection requiring ventilatory support and extra corporeal oxygenation in which oseltamivir and baloxavir were used in combination. Patient oxygen requirements and imaging improved significantly after treatment initiation, leading to an overall short period of therapy. We present the first case of a patient treated with this combination in the context of chronic kidney disease.
. 2020 May 22;21:e00819.
doi: 10.1016/j.idcr.2020.e00819. eCollection 2020.
Oseltamivir and Baloxavir: Dual Treatment for Rapidly Developing ARDS on a Patient With Renal Disease
Pool Tobar Vega[SUP] 1 [/SUP], Elena Caldeira[SUP] 1 [/SUP], Hasan Abad[SUP] 1 [/SUP], Peguy Saad[SUP] 1 [/SUP], Erik Lachance[SUP] 1 [/SUP]
Affiliations
- PMID: 32489873
- PMCID: PMC7256313
- DOI: 10.1016/j.idcr.2020.e00819
Abstract
Influenza is an annual epidemic disease that in severe cases can lead to the development of ARDS. Current practice recommends the routine use of neuraminidase inhibitors with emerging evidence for the use of endonuclease inhibitors. We present the case of a 22-year-old female with diabetes and IgG4 tubulo-interstitial nephritis that developed rapidly progressive ARDS from influenza infection requiring ventilatory support and extra corporeal oxygenation in which oseltamivir and baloxavir were used in combination. Patient oxygen requirements and imaging improved significantly after treatment initiation, leading to an overall short period of therapy. We present the first case of a patient treated with this combination in the context of chronic kidney disease.