Human-isolated H7N9 obtained internal genes from duck and human influenza viruses

[tetano]

J Infect. 2019 Mar 14. pii: S0163-4453(19)30077-5. doi: 10.1016/j.jinf.2019.03.008. [Epub ahead of print]
Human-isolated H7N9 obtained internal genes from duck and human influenza viruses.

Pu Z[SUP]1[/SUP], Yang J[SUP]1[/SUP], Shen X[SUP]1[/SUP], Irwin DM[SUP]2[/SUP], Shen Y[SUP]3[/SUP].
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PMID: 30880145 DOI: 10.1016/j.jinf.2019.03.008


[FONT=&quot]Recent studies in this journal revealed that some H7N9 viruses reassorted with duck AIVs, and then attained the ability to efficiently infect ducks.[/FONT][FONT=&quot]1,2[/FONT][FONT=&quot] H7N9 AIVs have been endemic in chicken since their emergence in China in February 2013.[/FONT][FONT=&quot]3[/FONT][FONT=&quot]

After its emergence, H7N9 viruses have evolved substantially, and have frequently reassorted, acquiring internal genes from other chicken H9N2 viruses, increasing the genetic diversity of H7N9 viruses.[/FONT][FONT=&quot]4[/FONT][FONT=&quot] This raises the concern that whether H7N9 can attain internal genes from other AIVs.[/FONT]



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