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Hum Vaccin Immunother . Co-administration of SARS-CoV-2 and influenza vaccines in healthcare workers: Results of two vaccination campaigns in a lar

tetano

Editor, Senior Moderator
Hum Vaccin Immunother


. 2023 Dec 15;19(3):2287282.
doi: 10.1080/21645515.2023.2287282. Epub 2023 Nov 28. Co-administration of SARS-CoV-2 and influenza vaccines in healthcare workers: Results of two vaccination campaigns in a large teaching hospital in Rome

Domenico Pascucci[SUP] 1 2 [/SUP], Alberto Lontano[SUP] 2 [/SUP], Luca Regazzi[SUP] 2 [/SUP], Eleonora Marziali[SUP] 2 [/SUP], Mario Cesare Nurchis[SUP] 2 3 [/SUP], Matteo Raponi[SUP] 4 [/SUP], Giuseppe Vetrugno[SUP] 1 5 [/SUP], Umberto Moscato[SUP] 2 4 [/SUP], Chiara Cadeddu[SUP] 2 [/SUP], Patrizia Laurenti[SUP] 2 4 [/SUP]



Affiliations
Abstract

The concurrent administration of COVID-19 and influenza vaccines has arisen as a promising approach to bolster protection against respiratory pathogens and improve vaccination rates. However, there remains a lack of data regarding the prevalence of co-administration across several vaccination campaigns, especially among healthcare workers (HCWs). Therefore, this study aims to shed light on the acceptance of co-administration strategies among HCWs during the two campaigns following the introduction of the anti-SARS-CoV-2 vaccine. A retrospective cohort study was conducted among the HCWs of the Fondazione Policlinico Universitario "A. Gemelli" IRCCS, a research hospital in Rome. Hospital administrative databases were accessed to gather information about vaccination for SARS-CoV-2 and influenza during the 2021/2022 and 2022/2023 vaccination campaigns. The study included 7399 HCWs. The co-administration of anti-SARS-CoV-2 and influenza vaccines presented a significant rise in 2022/2023 compared to the previous vaccination campaign (+38%): this was confirmed for every professional category, with the largest increases among resident doctors (+47%) and physicians (+44%), and also for every age category, but it was particularly evident for the youngest health professionals. The probability of co-administration uptake during the 2022/2023 campaign was significantly higher for males, and for those that received co-administration during the 2021/2022 campaign, while the probability was lower for nurses and administrative staff. This study highlights the co-administration procedure as a valuable and effective tool in annual vaccination campaigns for SARS-CoV-2 and influenza. The procedure's safety and streamlined logistics make it increasingly attractive for implementation, particularly among HCWs.

Keywords: COVID-19; Co-administration; SARS-CoV-2; healthcare workers; influenza; vaccine.

 
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