tetano
Editor, Senior Moderator
J Infect Public Health. 2012 Aug;5(4):275-80. doi: 10.1016/j.jiph.2011.12.006. Epub 2012 May 5.
Household transmission of 2009 H1N1 influenza virus in Yazd, Iran.
Behnaz F, Mohammadzadeh M, Sadeghian M.
Source
Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Electronic address: fatemah.behnaz@yahoo.com.
Abstract
OBJECTIVES:
The 2009 pandemic influenza A (H1N1) virus is a public health challenge. Notably, laboratory-confirmed cases do not represent the age group most susceptible to infection. To characterize the age distribution of all cases of H1N1 influenza, we studied the personal contacts of confirmed cases to identify the age group at the highest risk.
METHODS:
We investigated the family members of 162 laboratory-confirmed cases of 2009 H1N1 in Yazd, Iran. Family members were retrospectively asked whether they had ≥2 respiratory symptoms within 7days of the last contact with the associated index cases. The ages and symptoms of the patients as well as the interval between diagnosis and the onset of symptoms among household contacts were determined using a questionnaire.
RESULTS:
We identified 596 family members of index cases, 83 (13.9%) of whom developed acute respiratory illness. No acute respiratory illness was found in 104 families (64%); however, there were 2 cases in 15 families (9.3%) and ≥3 cases in 4 families (24%). Household contacts from 5 to 18years old were more susceptible to acute respiratory illness than those who were ≥51years old (RR=3.174, 95% CI 1.313-7.675 P-value=0.01).
CONCLUSION:
Individuals ≤18years old were most susceptible to infection by the H1N1 virus. Therefore, in low-income populations, prevention of the spread of H1N1 to this age group should be emphasized.
Copyright ? 2012 King Saud Bin Abdulaziz University for Health Sciences. Published by Elsevier Ltd. All rights reserved.
PMID:
23021649
[PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/23021649
Household transmission of 2009 H1N1 influenza virus in Yazd, Iran.
Behnaz F, Mohammadzadeh M, Sadeghian M.
Source
Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Electronic address: fatemah.behnaz@yahoo.com.
Abstract
OBJECTIVES:
The 2009 pandemic influenza A (H1N1) virus is a public health challenge. Notably, laboratory-confirmed cases do not represent the age group most susceptible to infection. To characterize the age distribution of all cases of H1N1 influenza, we studied the personal contacts of confirmed cases to identify the age group at the highest risk.
METHODS:
We investigated the family members of 162 laboratory-confirmed cases of 2009 H1N1 in Yazd, Iran. Family members were retrospectively asked whether they had ≥2 respiratory symptoms within 7days of the last contact with the associated index cases. The ages and symptoms of the patients as well as the interval between diagnosis and the onset of symptoms among household contacts were determined using a questionnaire.
RESULTS:
We identified 596 family members of index cases, 83 (13.9%) of whom developed acute respiratory illness. No acute respiratory illness was found in 104 families (64%); however, there were 2 cases in 15 families (9.3%) and ≥3 cases in 4 families (24%). Household contacts from 5 to 18years old were more susceptible to acute respiratory illness than those who were ≥51years old (RR=3.174, 95% CI 1.313-7.675 P-value=0.01).
CONCLUSION:
Individuals ≤18years old were most susceptible to infection by the H1N1 virus. Therefore, in low-income populations, prevention of the spread of H1N1 to this age group should be emphasized.
Copyright ? 2012 King Saud Bin Abdulaziz University for Health Sciences. Published by Elsevier Ltd. All rights reserved.
PMID:
23021649
[PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/23021649