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HKU discovery of new virus from deceased pigs - porcine parainfluenza 1 virus (PPIV-1)

Pathfinder

Editor, Senior Moderator
Translation Google

HKU discovery of new flu virus

HKU microbiological research team at the Sheung Shui Slaughterhouse a dead pig body, discovered a new influenza virus.

August 16, 2013 11:28 AM

HKU microbiological research team at the Sheung Shui Slaughterhouse a dead pig body, discovered a new influenza virus.

This virus research team named PPIV-1 (porcine parainfluenza virus 1, meaning "swine parainfluenza virus -1").

As long as the pork cooked thoroughly before eating, this flu virus is not expected to pose a major threat to humans.

HKU microbiologist Yuen Kwok-yung is one of participating in the study's senior investigator. He said that this variant of influenza virus might in turn transmitted to humans by the pigs.

He said that this new virus is closely related with certain human influenza virus, we have to deal with the swine flu virus like H1N1 or Nipah virus (Nipah virus) is the same careful attention to possible cases of pigs infected person.

http://www.scmpchinese.com/sc/hong-kong/10950/gang-da-fa-xian-xin-liu-gan-bing-du

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Credit: Giuseppe Michieli
http://www.flutrackers.com/forum/showthread.php?p=506645

J Gen Virol. 2013 Aug 5. [Epub ahead of print]

Identification and characterization of a novel paramyxovirus, porcine parainfluenza 1 virus, from deceased pigs.

Lau SK, Woo PC, Wu Y, Wong AY, Wong BH, Lau CC, Fan RY, Cai JP, Tsoi HW, Chan KH, Yuen KY.
Source
The University of Hong Kong.

Abstract
We describe the discovery and characterization of a novel paramyxovirus, porcine parainfluenza 1 virus (PPIV-1), from swine. The virus was detected in 12 (3.1%) of 386 nasopharyngeal and 2 (0.7%) of 303 rectal swab samples from 386 deceased pigs by RT-PCR, with viral load up to 106 copies/ml. Complete genome sequencing and phylogenetic analysis showed that PPIV-1 represented a novel paramyxovirus within Respirovirus, being most closely related to human parainfluenza virus 1 (HPIV-1) and Sendai virus (SeV). In contrast to HPIV-1, PPIV-1 possesses mRNA editing function in phosphoprotein gene. Moreover, PPIV-1 is unique among respiroviruses in having 2 G residues instead of 3-5 G residues following the A6-run at editing site. Nevertheless, PPIV-1, HPIV-1 and SeV shared common genomic features and may belong to a separate group under Respirovirus. The presence of PPIV-1 in mainly respiratory samples suggested possible association with respiratory disease, similar to HPIV-1 and SeV.

...
http://www.ncbi.nlm.nih.gov/pubmed/23918408
 
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