tetano
Editor, Senior Moderator
Vet Pathol. 2013 May 22. [Epub ahead of print]
High-Pathogenicity Avian Influenza Virus in the Reproductive Tract of Chickens.
Silva MS, Rissi DR, Pantin-Jackwood M, Swayne DE.
Source
Agricultural Research Service, US Department of Agriculture, Athens, GA, USA.
Abstract
Infection with high-pathogenicity avian influenza virus (HPAIV) has been associated with a wide range of clinical manifestations in poultry, including severe depression in egg production and isolation of HPAIV from eggs laid by infected hens. To evaluate the pathobiology in the reproductive tract of chickens, adult hens were inoculated intranasally with 3 HPAIV strains. All 3 strains induced lesions in the reproductive tract 36 to 72 hours after inoculation. Positive immunostaining was observed in all segments of the reproductive tract, occurring predominantly in stromal cells and superficial germinal epithelium of the ovary, in mucosal epithelial cells and less often glandular epithelium throughout the oviduct, and in vascular endothelium. This study generates important data and explains previously reported virus isolation from yolk, due to ovarian virus replication, and virus recovery from albumin, due to virus replication in epithelial cells in several segments of the oviduct.
KEYWORDS:
avian influenza virus, chickens, high pathogenicity, layers, reproductive tract
PMID:
23697482
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/23697482
High-Pathogenicity Avian Influenza Virus in the Reproductive Tract of Chickens.
Silva MS, Rissi DR, Pantin-Jackwood M, Swayne DE.
Source
Agricultural Research Service, US Department of Agriculture, Athens, GA, USA.
Abstract
Infection with high-pathogenicity avian influenza virus (HPAIV) has been associated with a wide range of clinical manifestations in poultry, including severe depression in egg production and isolation of HPAIV from eggs laid by infected hens. To evaluate the pathobiology in the reproductive tract of chickens, adult hens were inoculated intranasally with 3 HPAIV strains. All 3 strains induced lesions in the reproductive tract 36 to 72 hours after inoculation. Positive immunostaining was observed in all segments of the reproductive tract, occurring predominantly in stromal cells and superficial germinal epithelium of the ovary, in mucosal epithelial cells and less often glandular epithelium throughout the oviduct, and in vascular endothelium. This study generates important data and explains previously reported virus isolation from yolk, due to ovarian virus replication, and virus recovery from albumin, due to virus replication in epithelial cells in several segments of the oviduct.
KEYWORDS:
avian influenza virus, chickens, high pathogenicity, layers, reproductive tract
PMID:
23697482
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/23697482