High-dose flu vaccine appears to be effective at preventing post-influenza deaths among older adults

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Fast Facts

• Older adults are at high risk for serious complications from flu and account for a majority of flu-related deaths and hospitalizations. H3N2 influenza viruses typically hit this age group particularly hard and have been associated with higher mortality than infections by H1N1 or influenza B viruses.
• During the 2012-2013 season, when H3N2 viruses were dominant, the high-dose flu vaccine was 36 percent more effective at preventing deaths in the Medicare beneficiaries studied, compared to the standard-dose vaccine.
• When H1N1 viruses circulated during the 2013-2014 season, the high-dose vaccine was not significantly better than the standard-dose vaccine at preventing deaths

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