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HHS Viewer Guide to 'Fatal Contact: Bird Flu in America'

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DB

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http://www.abcnews.go.com/Health/story?id=1940818&page=1

HHS Viewer Guide to 'Fatal Contact: Bird Flu in America'

Frequently Asked Questions About Bird Flu





May 9, 2006 ? - The following is the Department of Health and Human Services' Viewers Guide to "Fatal Contact: Bird Flu in America," which airs on ABC Tuesday.
On Tuesday, May 9 at 8 p.m., the ABC television network will air a made-for-TV movie titled "Fatal Contact: Bird Flu in America." The movie follows an outbreak of the H5N1 avian flu virus from its origins in a Hong Kong market through its mutation into a pandemic virus that becomes easily transmittable from human to human and spreads rapidly around the world.
The Department of Health and Human Services has prepared a Viewer's Guide and some anticipated Questions and Answers to provide factual information for viewers of the movie.

Viewer's Guide


- The ABC Movie "Fatal Contact: Bird Flu in America" is a movie, not a documentary. It is a work of fiction designed to entertain and not a factual accounting of a real world event.
- There is no influenza pandemic in the world at this time.
- Also, it is important to remember that H5N1 avian influenza is almost exclusively a disease of birds. The H5N1 virus has not yet appeared in the U.S.
- Should the H5N1 virus appear in the U.S., it does not mean the start of a pandemic.
- An additional point to remember is that the next influenza pandemic could be substantially less severe than what the movie depicts or that occurred in 1918. For example, the influenza pandemics of 1957/58 and 1968/69 caused so much less illness and death than did the 1918/19 pandemic that many Americans at that time did not distinguish them from seasonal influenza and were unaware that a pandemic was underway.
- While the movie does serve to raise awareness about avian and pandemic flu, we hope it will inspire preparation - not panic. There are steps individuals, families and communities can take to prepare. You can keep a supply of food and medicines on hand in case you have to stay home, you can practice good public health measures like frequent hand washing and staying home when sick. There is good information available on www.pandemicflu.gov.
- The film does depict scenarios that could unfold should a severe pandemic ever develop, including limited availability of antivirals and vaccines as well as the potential for disruption of supplies, medicines and other essential services.
- The film also illustrates the expected months-long delay in developing an effective vaccine against a pandemic strain of influenza once it emerges. This is why, at the President's request, the Congress approved funding for the Department of Health and Human Services to make significant financial investments to improve the technology for vaccine development and to build up our domestic vaccine production capacity, to ensure more rapid availability of vaccine for the population in a pandemic.
- The film highlights an important aspect of planning - individual and community planning and cooperation that will be so vital to sustaining communities and neighborhoods during an extended wave of an influenza pandemic. HHS has developed an extensive set of planning documents, including planning checklists for businesses, schools, health care providers, community organizations and states as well as an individual and family planning guide. All of these materials are available at www.pandemicflu.gov.
- While the H5N1 virus has not yet appeared in the U.S., and there is no influenza pandemic in the world at this time, it is important for all Americans to be informed about this potential public health threat and some of the steps individual Americans can take to protect themselves and their families in the event of a pandemic.

Questions & Answers


Many people in the movie are seen wearing surgical masks. Will masks protect me?
<!-- page -->Surgical masks are recommended for health care workers who are subjected to repeated exposure to multiple patients. For health care workers performing certain medical procedures on infected patients, N95 respirators are recommended. Surgical masks are also recommended for patients who are infected to help reduce the potential for spread of virus when these people cough or sneeze. HHS will continue to review and update as needed its public health guidance on the use of masks and respirators by healthcare workers and by the general public.
The movie shows the virus spreading in many ways besides coughing or sneezing, such as handshakes, kissing, sharing drinks, etc. Is that correct?
Influenza virus is primarily spread by airborne droplets that reach the eyes, nose or mouth but can also spread by touching contaminated surfaces and then touching one's face. This highlights the importance of learning and practicing good personal hygiene, including:
Wash hands frequently with soap and water.
Cover your mouth and nose with a tissue when you cough or sneeze.
Put used tissues in a waste basket.
Cough or sneeze into your upper sleeve if you don't have a tissue.
Clean your hands after coughing or sneezing. Use soap and water or an alcohol-based hand cleaner.
Stay at home if you are sick.

The film indicates that there will be a shortage of Tamiflu (or other antivirals) in a pandemic. Will there be? And if so, what is the government doing to prevent that?
HHS is stockpiling enough antivirals to treat 25% of the U.S. population should a pandemic occur in the U.S. This figure is based on historical data from past pandemics indicating that roughly 25% of the population would get sick in a pandemic and would benefit from antiviral treatment if started early in the course of illness. To date, the U.S. government has purchased 26 million antiviral treatment courses and expects to have on hand a total of 81 million treatment courses by the end of 2008.
In the movie officials quickly find out that there is no vaccine available when the pandemic occurs nor will any be available for many months. Will we have vaccine available if a pandemic occurs?
There likely will be no vaccine initially available that precisely matches the pandemic strain when a pandemic begins. Because influenza viruses continually evolve and mutate, it is not possible to develop a vaccine until after the pandemic strain actually comes into existence. Only after the strain emerges, is isolated and characterized can a vaccine be developed and manufactured. Based upon current vaccine production processes and capacities, it will take at least 6 months to begin producing pandemic vaccine once a pandemic strain occurs.
HHS has been developing and stockpiling an experimental "pre-pandemic" H5N1 vaccine that may offer some level of immune protection should the H5N1 virus mutate into a pandemic strain. Having a stockpile of this vaccine for up to 20 million people, may help delay or lessen the initial impact of a pandemic while vaccine against the actual pandemic strain is developed and produced.
However, HHS is making significant financial investments to improve the technology for vaccine development and to build up our domestic vaccine production capacity, to ensure more rapid availability of vaccine for the population in a pandemic.
Many neighborhoods were quarantined in the film. Even the Governor of Virginia quarantined himself, his staff and his family from the rest of the world. Will the government quarantine people in a pandemic?
The purpose of quarantine is to separate people who have been potentially exposed to a contagious disease and may be infected but are not yet ill to stop the spread of that disease. The last large-scale quarantine measures that were imposed in this country were used in the early 20th century to contain outbreaks of plague, yellow fever, and smallpox.
<!-- page -->Today, quarantine typically refers to confining potentially infected persons to their homes or community-based facilities, usually on a voluntary basis. Quarantine can be used for a defined group of people who may have been exposed at a public gathering, or who may have been exposed while traveling, particularly overseas. In extreme cases, quarantine could apply to an entire geographic area, in which case a community may be closed off by sealing its borders or by a barricade, known as a "cordon sanitaire".
In the case of pandemic influenza, quarantine may be one of the public health tools employed in the early days of an emerging pandemic if efforts are undertaken to contain the outbreak before it spreads too widely. Once a pandemic has begun to spread, quarantine is not likely to be effective in controlling the spread, and instead efforts may turn to "social distancing." Social distancing includes measures to increase distance between individuals, such as staying home when ill unless seeking medical care, avoiding large gatherings, telecommuting, and school closures.
In the movie, we learn that the virus is beginning to develop resistance to Tamiflu, rendering the drug useless. Could that happen? If so, why are we buying so much Tamiflu for the stockpile?
Tamiflu, and another antiviral, Relenza, have shown effectiveness in treating influenza. Early evidence suggests that Tamiflu may be effective in treating those patients who have been infected with the H5N1 avian flu virus. While there have been a few reports of Tamiflu resistance developing on therapy, there has been no transmission of a resistant virus. The resistance developing on therapy has been associated with starting the drug late or using low doses of this drug. Tamiflu, when used at proper doses and started within a few days of the appearance of symptoms should be effective treatment of this infection.
Relenza has not been used in treating human H5N1 cases to date, as it has been unavailable in many countries that have had people infected with H5N1. But experts expect it would be an effective treatment also.
HHS is stockpiling enough antivirals to treat 25% of the U.S. population should a pandemic occur in the U.S. This figure is based on historical data from past pandemics indicating that roughly 25% of the population would get sick in a pandemic. To date, the U.S. government has purchased 26 million antiviral treatment courses and expects to have on hand a total of 81 million treatment courses by the end of 2008. Of its antiviral purchases, the U.S. is buying approximately 80% of its supply as Tamiflu and about 20% of its supply as Relenza. This is due in part to product availability but also to the need to diversify the supply so as to not rely solely on one medication.
Many essential services (e.g. electricity, food, water, etc.) become scarce in the film's scenario. Could that happen?
An especially severe influenza pandemic could lead to high levels of illness, death, social disruption, and economic loss. Everyday life would be disrupted because so many people in so many places become seriously ill at the same time. Impacts can range from school and business closings to the interruption of basic services such as public transportation and food delivery.
In addition, a substantial percentage of the world's population will require some form of medical care. Health care facilities can be overwhelmed, creating a shortage of hospital staff, beds, ventilators and other supplies. Non-traditional sites such as schools may need to be used for patient care to cope with demand.
The film depicted many people who simply walked off their jobs. Would that really occur?
<!-- page -->In a severe pandemic, it is very possible that up to 40% of a business' or organization's workforce will be out sick or at home taking care of sick family members. It is also possible that a small percentage of this amount will be people who are healthy but who may be too frightened to venture out into public.
The numbers of health-care workers and first responders available to work can be expected to be reduced as they will be at high risk of illness through exposure in the community and in health care settings, and some may have to miss work to care for ill family members.
What will be done with the overwhelming number of deceased bodies if we have a severe, 1918-like pandemic as was depicted in the film?
Addressing the possibility of a large number of deceased individuals in a pandemic is one of our top pandemic planning priorities. Currently, we are working on modeling studies to try to determine as clearly as we can what we could possibly expect in terms of numbers of deaths over the course of several pandemic waves. Until these studies are done, we won't be able to speculate on details of what we might or might not expect. We expect this work to be done in the next few months.
Regardless of whatever estimates are developed, it is highly unlikely that in the 21st Century in the U.S. that we would ever resort to mass graves. We are working with many government agencies (e.g. VA) as well as the private sector (e.g. the funeral industry, the cemetery industry) to develop guidance for states, local communities and others that maintains the dignity of the deceased, honors family wishes, and respects religious and social customs.
Deciding who gets vaccine was a major question in the film. In a real pandemic, how will you decide who gets vaccine first?
The greatest risk of hospitalization and death-as seen during the last two pandemics in 1957 and 1968 pandemics and during annual influenza-will be in infants, the elderly, and those with underlying health conditions. These individuals, along with health care providers, who are critical to maintaining a health care system in a pandemic, would likely be the first individuals to receive the first supplies of vaccine. However, in the 1918 pandemic, most deaths occurred in young adults, highlighting the need to remain flexible on determining priorities for vaccination groups based on the epidemiology of an emerging pandemic.
As part of planning efforts, two Federal advisory committees-the Advisory Committee on Immunization Practices and the National Vaccine Advisory Committee-have made recommendations for prioritizing critical populations that might receive the first supplies of vaccine. These recommendations can be found in the HHS Pandemic Plan, which is available at www.pandemicflu.gov.
In the movie, the Virginia governor's son dies because he cannot get diabetes medicine; other drugs are not available in pharmacies.
Essential supplies, including medicine, may become unavailable during a pandemic. As part of effective planning, individuals and families should talk to their doctor about how to maintain adequate access to prescription medications.
 
Re: HHS Viewer Guide to 'Fatal Contact: Bird Flu in America'

Ok, how many times has the government issued a viewers guide for a made for TV movie????

Zero before today.

It seems as though the government officials are panicking over this movie.

They are trying to do damage control before there is any damage. They aren't giving people the benefit of the doubt that they can discern reality from fiction.
 
Re: US Dept of Interior on 'Fatal Contact: Bird Flu in America'

Re: US Dept of Interior on 'Fatal Contact: Bird Flu in America'

>>> Distribution DIST_A:DontReplyToSender 5/9/2006 9:17:08 AM
>>>
(NOTE TO SUPERVISORS: Please ensure employees without access to e-mail receive a paper copy of this message.)
Memorandum
To: All Department of the Interior Employees
From: Tom Weimer, Assistant Secretary,
Policy, Management and Budget
Subject: ABC Movie on Bird Flu Pandemic
As many of you are aware, ABC will broadcast a made-for-TV movie tonight, May 9 (8-10 pm EST) called "Fatal Contact: Bird Flu in America."
This
fictionalized account portrays an outbreak of the H5N1 avian flu virus
from its origins in a Hong Kong market through its mutation into a pandemic virus that becomes transmittable from human to human and spreads rapidly around the world.
This broadcast may lead to an increase in public and news media calls concerning the Federal Government's avian influenza preparedness and
response efforts. As public concern about avian influenza increases, it is important to separate fact from fiction.
To help clarify any misconceptions about avian influenza that may arise
from this movie, DOI and its federal and state partners have prepared public service informational materials, some of which will be distributed to media before and after May 9, while others will be posted to federal
websites.
Also, ABC News has decided to do a three-part news series for its affiliated stations in conjunction with the movie. The three public service programs will be available to all ABC affiliated stations across the Nation to run on Monday, Tuesday and Wednesday's late afternoon/evening news programs (5 to 11 p.m.). The Monday program will discuss how high pathogenicity avian influenza travels; Tuesday will be
"The Movie: Fact or Fiction"; and Wednesday will be about avian influenza vaccines.
There are several key facts that Interior employees and the public should keep in mind about this movie. It is not a documentary. It is a work of
fiction designed to entertain and not a factual accounting of a real world event.

There is no influenza pandemic in the world at this time. The most recent Asian strain of highly pathogenic H5N1 avian influenza virus is almost
exclusively a disease of birds and even in birds, has not yet appeared in North or South America.

The risk of high path H5N1 transmission from wild birds to humans is extremely low. That said, the potential for migratory birds to carry this virus to North America does exist and we have a responsibility to plan and prepare accordingly. The Department and its bureaus (particularly USGS,
FWS and NPS) have been closely involved in the government-wide effort to plan for and respond to a pandemic, including the Implementation Plan for the National Strategy for Pandemic Influenza, which was released last week.
Should this virus appear in the United States, it does not mean the start of a pandemic. Moreover, the next influenza pandemic could be less severe than what the movie depicts or that occurred in 1918. For example, the
influenza pandemics of 1957/58 and 1968/69 caused so much less illness and death than did the 1918/19 pandemic that many Americans at that time did not distinguish them from seasonal influenza and were unaware that a pandemic was underway.

While the movie does serve to raise awareness about avian and pandemic
flu, we hope it should inspire preparation - not panic. It is important for all Americans to be informed about this potential public health threat and we advise looking carefully at the recommended steps individual Americans can take to protect themselves, their families and communities in the event of a pandemic.
You can practice good public health measures like frequent hand washing
and staying home when sick. You can keep a supply of food and medicines on hand in case you have to stay home, a wise precaution for any type of emergency. There is good information available on
www.pandemicflu.gov and on the DOI web site at www.doi.gov/avianflu.html.

Additional information on avian influenza, employee health, wild bird monitoring and management, safety guidelines for hunters and wildlife watchers and other information for DOI employees, State wildlife agencies and the public are online at the sites listed below.
Federal Government-wide Avian Influenza Information:
www.pandemicflu.gov
Department of the Interior-wide Avian Influenza Information:
www.doi.gov/avianflu.html.
U.S. Geological Survey National Wildlife Health Center Avian
Influenza:
http://www.nwhc.usgs.gov/disease_information/avian_influenza/index.jsp

Homeland Security Council's National Strategy for Pandemic Influenza:
www.whitehouse.gov/homeland/nspi.pdf
Implementation Plan for the National Strategy for Pandemic Influenza:
www.whitehouse.gov/infocus/pandemicflu/
Interagency Strategic Plan:
www.doi.gov/issues/birdflu_strategicplan.pdf
U.S. Department of Agriculture:
www.usda.gov/birdflu


 
Re: HHS Viewer Guide to 'Fatal Contact: Bird Flu in America'

Looks like they are anticipating the movie to strike a cord with americans.

It will be interesting to see how this plays out.

It is ok for people to panic, as long as it is not excessive panic.

Panic can drive people to take action and right now everyone needs to be preparing for this event.
[SIZE=+0][/SIZE]
 
Re: HHS Viewer Guide to 'Fatal Contact: Bird Flu in America'

And the disinformation begins. Likening the H5N1 possible pandemic to the ones in '57 and '68 is especially reprehensible. Neither of those was an avian flu virus. The pandemic of 1918 did come directly from birds. And suggesting the government is in control and testing vast quantities of birds in Alaska is laughable. Entire flocks could be dying and who would be the wiser if the epizootic happened at some distance to human habitation? Nevertheless, it will be spreading into the North American bird populations if not now, then soon. I appreciate them trying to take a stab at both getting people to prep and giving people a hint at the possibility of pandemic, but not when they alter the facts to suit their agenda.
 
Re: HHS Viewer Guide to 'Fatal Contact: Bird Flu in America'

Shannon said:
And the disinformation begins. Likening the H5N1 possible pandemic to the ones in '57 and '68 is especially reprehensible. Neither of those was an avian flu virus.

H3N2 and H2N2 are both AI viruses. These were the viruses associated with 1957 and 1968/69 pandemics.
 
Re: HHS Viewer Guide to 'Fatal Contact: Bird Flu in America'

They both contained parts of those viruses but, they did not come directly from birds as did the flu of 1918. The danger is if the virus does move directly from avian to humans. And as it has already overcome the huge obstacle of directly infecting humans, our eyes shhould be focused on the distinct possibility it may make further moves in our direction.
 
Re: HHS Viewer Guide to 'Fatal Contact: Bird Flu in America'

Shannon said:
They both contained parts of those viruses but, they did not come directly from birds as did the flu of 1918. The danger is if the virus does move directly from avian to humans. And as it has already overcome the huge obstacle of directly infecting humans, our eyes shhould be focused on the distinct possibility it may make further moves in our direction.

H3N2 and H2N2 are type A influenza. All type A influenza's are avian, regardless of whether they reassorted or recombined in another species; they are still avian influenza viruses.

It is believed that the 1918 virus (H1N1) made a direct jump to humans and became readily transmissable H2H. It is not known whether H5N1 will do the same.
 
Re: HHS Viewer Guide to 'Fatal Contact: Bird Flu in America'

KC, I agree that birds are the reservoir for all influenza A. However the point I was trying to make and somehow evidently failed to do was, that avian viruses rarely infect humans. There is a significant difference between a reassortment from a strain that typically infects humans and one that was thought to only infect birds. I'm sorry for the evident miscommunication.

http://www.cdc.gov/flu/avian/gen-info/flu-viruses.htm

The Virus & Its Spread >
Influenza Viruses
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On this page:
http://www.flutrackers.com/forum/Types, Subtypes, and Strains There are three types of influenza viruses: A, B, and C. Only influenza A viruses are further classified by subtype on the basis of the two main surface glycoproteins hemagglutinin (HA) and neuraminidase (NA). Influenza A subtypes and B viruses are further classified by strains.
Human Influenza Viruses and Avian Influenza A Viruses Humans can be infected with influenza types A, B, and C viruses. Subtypes of influenza A that are currently circulating among people worldwide include H1N1, H1N2, and H3N2 viruses.
Wild birds are the natural host for all known subtypes of influenza A viruses. Typically, wild birds do not become sick when they are infected with avian influenza A viruses. However, domestic poultry, such as turkeys and chickens, can become very sick and die from avian influenza, and some avian influenza A viruses also can cause serious disease and death in wild birds.
Low Pathogenic versus Highly Pathogenic Avian Influenza A Viruses Avian influenza A virus strains are further classified as low pathogenic (LPAI) or highly pathogenic (HPAI) on the basis of specific molecular genetic and pathogenesis criteria that require specific testing. Most avian influenza A viruses are LPAI viruses that are usually associated with mild disease in poultry. In contrast, HPAI viruses can cause severe illness and high mortality in poultry. More recently, some HPAI viruses (e.g., H5N1) have been found to cause no illness in some poultry, such as ducks. LPAI viruses have the potential to evolve into HPAI viruses and this has been documented in some poultry outbreaks. Avian influenza A viruses of the subtypes H5 and H7,including H5N1, H7N7, and H7N3 viruses, have been associated with HPAI, and human infection with these viruses have ranged from mild (H7N3, H7N7) to severe and fatal disease (H7N7, H5N1). Human illness due to infection with LPAI viruses has been documented, including very mild symptoms (e.g., conjunctivitis) to influenza-like illness. Examples of LPAI viruses that have infected humans include H7N7, H9N2, and H7N2.
In general, direct human infection with avian influenza viruses occurs very infrequently, and has been associated with direct contact (e.g., touching) infected sick or dead infected birds (domestic poultry).
http://www.flutrackers.com/forum/How Influenza Viruses Change: Drift and Shift Influenza viruses are dynamic and are continuously evolving. Influenza viruses can change in two different ways: antigenic drift and antigenic shift. Influenza viruses are changing by antigenic drift all the time, but antigenic shift happens only occasionally. Influenza type A viruses undergo both kinds of changes; influenza type B viruses change only by the more gradual process of antigenic drift.
Antigenic drift refers to small, gradual changes that occur through point mutations in the two genes that contain the genetic material to produce the main surface proteins, hemagglutinin, and neuraminidase. These point mutations occur unpredictably and result in minor changes to these surface proteins. Antigenic drift produces new virus strains that may not be recognized by antibodies to earlier influenza strains. This process works as follows: a person infected with a particular influenza virus strain develops antibody against that strain. As newer virus strains appear, the antibodies against the older strains might not recognize the "newer" virus, and infection with a new strain can occur. This is one of the main reasons why people can become infected with influenza viruses more than one time and why global surveillance is critical in order to monitor the evolution of human influenza virus stains for selection of which strains should be included in the annual production of influenza vaccine. In most years, one or two of the three virus strains in the influenza vaccine are updated to keep up with the changes in the circulating influenza viruses. For this reason, people who want to be immunized against influenza need to be vaccinated every year.
Antigenic shift refers to an abrupt, major change to produce a novel influenza A virus subtype in humans that was not currently circulating among people (see more information below under Influenza Type A and Its Subtypes). Antigenic shift can occur either through direct animal (poultry)-to-human transmission or through mixing of human influenza A and animal influenza A virus genes to create a new human influenza A subtype virus through a process called genetic reassortment. Antigenic shift results in a new human influenza A subtype. A global influenza pandemic (worldwide spread) may occur if three conditions are met:
  • A new subtype of influenza A virus is introduced into the human population.
  • The virus causes serious illness in humans.
  • The virus can spread easily from person to person in a sustained manner.
http://www.flutrackers.com/forum/Types, Subtypes, and Strains Influenza Type A and Its Subtypes Influenza type A viruses can infect people, birds, pigs, horses, and other animals, but wild birds are the natural hosts for these viruses. Influenza type A viruses are divided into subtypes and named on the basis of two proteins on the surface of the virus: hemagglutinin (HA) and neuraminidase (NA). For example, an “H7N2 virus” designates an influenza A subtype that has an HA 7 protein and an NA 2 protein. Similarly an “H5N1” virus has an HA 5 protein and an NA 1 protein. There are 16 known HA subtypes and 9 known NA subtypes. Many different combinations of HA and NA proteins are possible. Only some influenza A subtypes (i.e., H1N1, H1N2, and H3N2) are currently in general circulation among people. Other subtypes are found most commonly in other animal species. For example, H7N7 and H3N8 viruses cause illness in horses, and H3N8 also has recently been shown to cause illness in dogs.
Only influenza A viruses infect birds, and all known subtypes of influenza A viruses can infect birds. However, there are substantial genetic differences between the influenza A subtypes that typically infect birds and those that infect both people and birds. Three prominent subtypes of the avian influenza A viruses that are known to infect both birds and people are:
Influenza A H5 Nine potential subtypes of H5 are known. H5 infections, such as HPAI H5N1 viruses currently circulating in Asia and Europe, have been documented among humans and sometimes cause severe illness or death.
Influenza A H7 Nine potential subtypes of H7 are known. H7 infection in humans is rare but can occur among persons who have direct contact with infected birds. Symptoms may include conjunctivitis and/or upper respiratory symptoms. H7 viruses have been associated with both LPAI (e.g., H7N2, H7N7) and HPAI (e.g., H7N3, H7N7), and have caused mild to severe and fatal illness in humans.
Influenza A H9 Nine potential subtypes of H9 are known; influenza A H9 has rarely been reported to infect humans. However, this subtype has been documented only in a low pathogenic form.
Influenza Type B Influenza B viruses are usually found only in humans. Unlike influenza A viruses, these viruses are not classified according to subtype. Influenza B viruses can cause morbidity and mortality among humans, but in general are associated with less severe epidemics than influenza A viruses. Although influenza type B viruses can cause human epidemics, they have not caused pandemics.
Influenza Type C Influenza type C viruses cause mild illness in humans and do not cause epidemics or pandemics. These viruses are not classified according to subtype.
Strains Influenza B viruses and subtypes of influenza A virus are further characterized into strains. There are many different strains of influenza B viruses and of influenza A subtypes. New strains of influenza viruses appear and replace older strains. This process occurs through antigenic drift. When a new strain of human influenza virus emerges, antibody protection that may have developed after infection or vaccination with an older strain may not provide protection against the new strain. Therefore, the influenza vaccine is updated on a yearly basis to keep up with the changes in influenza viruses.
Page last modified November 18, 2005
 
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