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Hemagglutinin Receptor Binding of a Human Isolate of Influenza A(H10N8) Virus

tetano

Editor, Senior Moderator
Emerg Infect Dis. 2015 Jul;21(7):1197-201. doi: 10.3201/eid2107.141755.
[h=1]Hemagglutinin Receptor Binding of a Human Isolate of Influenza A(H10N8) Virus.[/h] Ramos I, Mansour M, Wohlbold TJ, Ermler ME, Hirsh A, Runstadler JA, Fernandez-Sesma A, Krammer F.
[h=3]Abstract[/h] Three cases of influenza A(H10N8) virus infection in humans have been reported; 2 of these infected persons died. Characterization of the receptor binding pattern of H10 hemagglutinin from avian and human isolates showed that both interact weakly with human-like receptors and maintain strong affinity for avian-like receptors.


[h=4]KEYWORDS:[/h] avian influenza; emerging influenza; hemagglutinin receptor binding; influenza; influenza A(H10N7); influenza A(H10N8) virus; influenza virus; sialic acid; viruses

PMID: 26079843 [PubMed - in process] Free full text
 
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