tetano
Editor, Senior Moderator
Heliyon
. 2024 May 31;10(11):e32164.
doi: 10.1016/j.heliyon.2024.e32164. eCollection 2024 Jun 15. Transmissibility of the variant of concern for SARS-CoV-2 in six regions
Hongjie Wei[SUP] 1 [/SUP], Yunkang Zhao[SUP] 1 [/SUP], Jia Rui[SUP] 1 2 3 [/SUP], Kangguo Li[SUP] 1 [/SUP], Buasiyamu Abudunaibi[SUP] 1 [/SUP], Zeyu Zhao[SUP] 1 [/SUP], Wentao Song[SUP] 1 [/SUP], Yao Wang[SUP] 1 [/SUP], Qiuping Chen[SUP] 1 2 3 [/SUP], Hong Liu[SUP] 1 [/SUP], Shuo Zhang[SUP] 1 [/SUP], Xiaojun Li[SUP] 4 [/SUP], Kaiwei Luo[SUP] 4 [/SUP], Laurent Gavotte[SUP] 3 [/SUP], Roger Frutos[SUP] 2 [/SUP], Tianmu Chen[SUP] 1 [/SUP]
Affiliations
Introduction: Differences in transmissibility of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) in different districts are hard to assess. To address this, our study focused on calculating the Real-time reproduction number (R [SUB]t[/SUB] ) for these variants in different regions.
Methods: According to the criteria defined by the World Health Organization (WHO), the global landscape was categorized into six distinct regions. In each region, the predominant SARS-CoV-2 variant was first identified based on the proportion of variant sequencing analysis results. Then, using serial interval (SI) parameters, we calculated R [SUB]t[/SUB] for the relevant Variant of Concern (VOC) in each region. This approach enabled us to compare the R [SUB]t[/SUB] values of the same variant across different regions and analyze the transmissibility of each region's variant in relation to the overall situation in that region.
Results: The progression of VOC for SARS-CoV-2 shows regional variations. However, a common sequence of evolution is observed: Wild-type → Alpha → Beta → Delta → Omicron. Moreover, an increasing trend is discerned within diverse regions where the shift in R [SUB]t[/SUB] of distinct VOC corresponds with the overarching R [SUB]t[/SUB] route of SARS-CoV-2 in specific regions.
Conclusion: As the COVID-19 pandemic advances, regional epidemiological trends are aligning, likely due to similar virus mutations and shared public health strategies, suggesting opportunities for standardized global responses.
Keywords: Period of dominant variants; Real-time reproduction number; SARS-CoV-2; Six regions.
. 2024 May 31;10(11):e32164.
doi: 10.1016/j.heliyon.2024.e32164. eCollection 2024 Jun 15. Transmissibility of the variant of concern for SARS-CoV-2 in six regions
Hongjie Wei[SUP] 1 [/SUP], Yunkang Zhao[SUP] 1 [/SUP], Jia Rui[SUP] 1 2 3 [/SUP], Kangguo Li[SUP] 1 [/SUP], Buasiyamu Abudunaibi[SUP] 1 [/SUP], Zeyu Zhao[SUP] 1 [/SUP], Wentao Song[SUP] 1 [/SUP], Yao Wang[SUP] 1 [/SUP], Qiuping Chen[SUP] 1 2 3 [/SUP], Hong Liu[SUP] 1 [/SUP], Shuo Zhang[SUP] 1 [/SUP], Xiaojun Li[SUP] 4 [/SUP], Kaiwei Luo[SUP] 4 [/SUP], Laurent Gavotte[SUP] 3 [/SUP], Roger Frutos[SUP] 2 [/SUP], Tianmu Chen[SUP] 1 [/SUP]
Affiliations
- PMID: 38868071
- PMCID: PMC11168441
- DOI: 10.1016/j.heliyon.2024.e32164
Introduction: Differences in transmissibility of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) in different districts are hard to assess. To address this, our study focused on calculating the Real-time reproduction number (R [SUB]t[/SUB] ) for these variants in different regions.
Methods: According to the criteria defined by the World Health Organization (WHO), the global landscape was categorized into six distinct regions. In each region, the predominant SARS-CoV-2 variant was first identified based on the proportion of variant sequencing analysis results. Then, using serial interval (SI) parameters, we calculated R [SUB]t[/SUB] for the relevant Variant of Concern (VOC) in each region. This approach enabled us to compare the R [SUB]t[/SUB] values of the same variant across different regions and analyze the transmissibility of each region's variant in relation to the overall situation in that region.
Results: The progression of VOC for SARS-CoV-2 shows regional variations. However, a common sequence of evolution is observed: Wild-type → Alpha → Beta → Delta → Omicron. Moreover, an increasing trend is discerned within diverse regions where the shift in R [SUB]t[/SUB] of distinct VOC corresponds with the overarching R [SUB]t[/SUB] route of SARS-CoV-2 in specific regions.
Conclusion: As the COVID-19 pandemic advances, regional epidemiological trends are aligning, likely due to similar virus mutations and shared public health strategies, suggesting opportunities for standardized global responses.
Keywords: Period of dominant variants; Real-time reproduction number; SARS-CoV-2; Six regions.