tetano
Editor, Senior Moderator
Heliyon
. 2021 Nov;7(11):e08412.
doi: 10.1016/j.heliyon.2021.e08412. Epub 2021 Nov 16.
Superiority of lymphocyte ratio over total leukocyte count in detecting the severity of COVID- 19 pneumonia
Rawaa Hadi Shareef[SUP] 1 [/SUP], Zinah Dhiaa Zwain[SUP] 2 [/SUP], Wadhah Abdulhussian Mahbuba[SUP] 3 [/SUP]
Affiliations
Abstract
Background: Coronavirus disease (COVID-19) is an infectious disease caused by a recently discovered coronavirus. Blood test including complete blood count is crucial in diagnosing of several viral and bacterial infection.
Aims: This study aimed to assess the association between lymphocyte ratio and other WBC types and severity of COVID-19 pneumonia.
Methods: The design of this study was a cross-sectional study. A complete blood count and erythrocyte sedimentation rate (ESR) was done for one hundred twenty-six COVID-19 patients (76 males and 50 females; aged 20-70 years). Patients were randomly recruited from multicenter in Al-Najaf Governorate, Iraq.
Results: The study had revealed an inverse correlation between severity of COVID-19 infection and both lymphocytes and monocytes ratio even in patients with normal WBC count. Additionally, there was a direct correlation between platelets and leukocyte count. The relation between leukocyte count and ESR level was significant in a patient with elevated WBC only.
Conclusion: Lymphocytes and monocyte ratios inpatient with COVID-19 infection can be used as predictors for the severity of infection. Increased leukocyte count resulted in increases in platelets inpatient with COVID-19.
Keywords: Coronavirus; Lymphocytes; Monocytes; White blood cells.
. 2021 Nov;7(11):e08412.
doi: 10.1016/j.heliyon.2021.e08412. Epub 2021 Nov 16.
Superiority of lymphocyte ratio over total leukocyte count in detecting the severity of COVID- 19 pneumonia
Rawaa Hadi Shareef[SUP] 1 [/SUP], Zinah Dhiaa Zwain[SUP] 2 [/SUP], Wadhah Abdulhussian Mahbuba[SUP] 3 [/SUP]
Affiliations
- PMID: 34805573
- PMCID: PMC8592846
- DOI: 10.1016/j.heliyon.2021.e08412
Abstract
Background: Coronavirus disease (COVID-19) is an infectious disease caused by a recently discovered coronavirus. Blood test including complete blood count is crucial in diagnosing of several viral and bacterial infection.
Aims: This study aimed to assess the association between lymphocyte ratio and other WBC types and severity of COVID-19 pneumonia.
Methods: The design of this study was a cross-sectional study. A complete blood count and erythrocyte sedimentation rate (ESR) was done for one hundred twenty-six COVID-19 patients (76 males and 50 females; aged 20-70 years). Patients were randomly recruited from multicenter in Al-Najaf Governorate, Iraq.
Results: The study had revealed an inverse correlation between severity of COVID-19 infection and both lymphocytes and monocytes ratio even in patients with normal WBC count. Additionally, there was a direct correlation between platelets and leukocyte count. The relation between leukocyte count and ESR level was significant in a patient with elevated WBC only.
Conclusion: Lymphocytes and monocyte ratios inpatient with COVID-19 infection can be used as predictors for the severity of infection. Increased leukocyte count resulted in increases in platelets inpatient with COVID-19.
Keywords: Coronavirus; Lymphocytes; Monocytes; White blood cells.