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Heart Lung . High incidence and mortality of pneumothorax in critically Ill patients with COVID-19

tetano

Editor, Senior Moderator
Heart Lung


. 2020 Oct 14;S0147-9563(20)30397-6.
doi: 10.1016/j.hrtlng.2020.10.002. Online ahead of print.
High incidence and mortality of pneumothorax in critically Ill patients with COVID-19


Xiao-Hui Wang[SUP] 1 [/SUP], Jun Duan[SUP] 1 [/SUP], Xiaoli Han[SUP] 1 [/SUP], Xinzhu Liu[SUP] 1 [/SUP], Junhao Zhou[SUP] 2 [/SUP], Xue Wang[SUP] 1 [/SUP], Linxiao Zhu[SUP] 1 [/SUP], Huaming Mou[SUP] 3 [/SUP], Shuliang Guo[SUP] 4 [/SUP]



Affiliations

Abstract

Background: The clinical characteristics of the patients with COVID-19 complicated by pneumothorax have not been clarified.
Objectives: To determine the epidemiology and risks of pneumothorax in the critically ill patients with COVID-19.
Methods: Retrospectively collecting and analysing medical records, laboratory findings, chest X-ray and CT images of 5 patients complicated by pneumothorax.
Results: The incidence of pneumothorax was 10% (5/49) in patients with ARDS, 24% (5/21) in patients receiving mechanical ventilation, and 56% (5/9) in patients requiring invasive mechanical ventilation, with 80% (4/5) patients died. All the 5 patients were male and aged ranging from 54 to 79 years old. Pneumothorax was most likely to occur 2 weeks after the beginning of dyspnea and associated with reduction of neuromuscular blockers, recruitment maneuver, severe cough, changes of lung structure and function.
Conclusions: Pneumothorax is a frequent and fatal complication of critically ill patients with COVID-19.

Keywords: COVID-19; Coronavirus disease 2019(COVID-19); Epidemiology; Mechanism; Mortality; Pneumothorax; Prevention.
 
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