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Healthcare (Basel) . Facial Diplegia-Complication or Manifestation of SARS-CoV-2 Infection? A Case Report and Systemic Literature Review

tetano

Editor, Senior Moderator
Healthcare (Basel)


. 2021 Nov 2;9(11):1492.
doi: 10.3390/healthcare9111492.
Facial Diplegia-Complication or Manifestation of SARS-CoV-2 Infection? A Case Report and Systemic Literature Review


Anna K Szewczyk[SUP] 1 [/SUP], Urszula Skrobas[SUP] 1 [/SUP], Anna Jamroz-Wiśniewska[SUP] 1 [/SUP], Krystyna Mitosek-Szewczyk[SUP] 2 [/SUP], Konrad Rejdak[SUP] 1 [/SUP]



Affiliations

Abstract

Since the outbreak of the new coronavirus, healthcare systems around the world have witnessed not only COVID-19 symptoms but also long-term complications of the aforementioned, including neurological problems. We report a clinical case of an adult patient with bilateral facial nerve palsy and progressive ascending paresis of the limbs after contracting the novel coronavirus (COVID-19). Additionally, the systematic review aimed to identify and summarize specific clinical features, outcomes and complications of the studies focusing on bilateral facial diplegia as a sequela of COVID-19 infection. The total number of analyzed patients was 15. Only one patient was diagnosed with isolated bilateral palsy; the rest had Guillain-Barré Syndrome (GBS). With one exception, all the presented cases had favorable outcomes, with facial palsy recovery from slight to almost complete. In patients with a confirmed COVID-19 diagnosis, bilateral facial palsy may be an isolated symptom as well as a variant of GBS. Symptoms of cranial nerve damage during a COVID-19 infection may explain the appearance of facial nerve damage. In order to clarify the spectrum of neurological manifestations and a causal relation between SARS-CoV-2, COVID-19 vaccination and neurological symptoms, direct attention towards the study of this virus is crucial. It seems reasonable to recognize human coronavirus as another potential GBS trigger.

Keywords: Bell’s palsy; COVID-19; COVID-19 vaccination; Guillain-Barré Syndrome; SARS-CoV-2; peripheral facial nerve palsy; peripheral nervous system disease.
 
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