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Has H5N1 disappeared from Egypt?

Giuseppe

Emeritus
Has H5N1 disappeared from Egypt? <HR style="COLOR: #cccccc; BACKGROUND-COLOR: #cccccc" SIZE=1><!-- / icon and title --><!-- message -->

The false reassurance that H5N1 would not be transmissible as H7N9 (since all these papers stating the pandemic potential of the novel strain in contrast with the ferret-transmissibility-defective H5N1) has driven most of media outlets and - most importantly - the WHO & other intl agencies to forget Egypt as birdflu viruses hotbed.

We collected hundreds of confirmed and suspected cases in the past from various egyptian governorates and then, suddenly, not a single case or cluster appeared.

Is this possible?

Yes, of course. If the virus underwent some major genes constellation mutations, drifting it from human and perhaps from chickens.

On the other hand, if the virus remains the same as we have known during the last seven years at least, human cases must be occurring actually in Egypt in number not inferior that in the recent past.

Why does the WHO not report anything from Egypt?

At least a call for surveillance, vigilance?

Is it wise to leave an avian influenza natural hotbed completely blinded?

MERS & H7N9 are obscuring in a worrying manner H5N1 especially in war-torne regions, such Egypt and ME in general.

GM
 
Re: Has H5N1 disappeared from Egypt?

From the WHO chart below it is apparent that since 2011 reporting on human H5N1 cases has decreased by 90% - from 39 in 2011 to 4 so far in 2013:


WHOh5n1chartsept2013.webp
 
Re: Has H5N1 disappeared from Egypt?

[Source: US National Library of Medicine, full page: (LINK).]


Clin Infect Dis. 2013 May;56(9):1213-5. doi: 10.1093/cid/cit051. Epub 2013 Feb 5.

Editorial commentary: pandemic H5N1: receding risk or coming catastrophe?

Morens DM.


Comment on Assessment of serosurveys for H5N1. [Clin Infect Dis. 2013]

Assessment of serosurveys for H5N1.Toner ES, Adalja AA, Nuzzo JB, Inglesby TV, Henderson DA, Burke DS. Clin Infect Dis. 2013 May; 56(9):1206-12. Epub 2013 Feb 5.

PMID: 23386632 [PubMed - indexed for MEDLINE]

PMCID: PMC3657493 [Available on 2014/5/1]


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Re: Has H5N1 disappeared from Egypt?

Giuseppe poses the question of whether or not H5N1 is still infecting humans in Egypt. Among all the world's countries that have reported human H5N1 infections, Egypt only trails Indonesia in the total number of reported human H5N1 infections (Indonesia - 193 cases, Egypt -173 cases).

While the number of world-wide cases has been declining since 2009, it is unclear whether the number of human infections is actually declining or the H5N1 cases are not being officially reported. Political upheaval and strife can affect surveillance, identification, and cases reporting.

There has been an average of 12 H5N1 cases in each of the five preceding years (2008-2012) in the four-month period from Sept - Dec. Through August 29, the official WHO count for 2013 is 27 cases. If the world accumulates 12 more cases between now and December 31, the total count of H5N1 cases for 2013 will exceed the count for 2012 (32). While current media attention is focused on avian influenza H7N9 and MERS-CoV, H5N1 still poses a threat in Egypt as well as elsewhere.
 
Re: Has H5N1 disappeared from Egypt?

This may not account for everything, but I think at least part of the reason is that surveillance was interrupted by the Arab spring. NAMRU3, at least, was evacuated on more than one occasion. They had been heavily involved with respiratory disease surveillance and outbreak response.
 
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