Re: H7N9, Guangdong: First human case detected - confirmed positive by China CDC
Translation Google
Son had fever patients are negative for H7N9 screening temporary
Ocean News Time: 2013-08-11 Source: Guangzhou Daily Author: Xuehua Qin Zhongyang Wu Yan
Guangdong confirmed one case of human infection with H7N9 avian influenza 96 close contacts of 95 people without exception
According to the Provincial Health Department on August 10 briefing, Huizhou found one case of suspected human infection of H7N9 avian influenza has been confirmed. From the evening of 9 patients had Huizhou Central People's Hospital transferred to the First Affiliated Hospital of Guangzhou Institute of Respiratory Diseases treated, the patient's condition was still critical. 96 close contacts,
there are 54 medical observation lift, 42 need to continue medical observation. The son of nine patients with low fever evening, body temperature 37.8 ℃, 10 am screening H7N9 was negative, with no fever, chest X-ray and blood examination was normal. The remaining 95 close contacts caught no exception.
Boluo suspected cases confirmed yesterday
Guangdong Provincial Health Department reported on August 10, Guangdong Province confirmed case of human infection of H7N9 avian influenza.
Patients Moumou, female, 51 years old, who lives in the town of Huizhou City, Yokogawa Hedong Road market towns, market towns in the Boro job market poultry slaughter. Patients with a high fever a week on August 3 at noon to Huizhou Central People's Hospital for treatment, "the fever investigation because of" admitted to hospital. Evening of August 9 Go First Affiliated Hospital of Guangzhou Institute of Respiratory Diseases.
August 9, the Guangdong Provincial Center for Disease Control reports of test results in patients infected with human H7N9 avian influenza virus nucleic acid positive. August 10, the Chinese Center for Disease Control laboratory human infection of H7N9 avian influenza review virus nucleic acid positive. Guangdong Provincial Health Department based on expert clinical manifestations, laboratory and epidemiological findings, etc., to diagnose the infection of H7N9 human cases of avian influenza confirmed cases. First Affiliated Hospital of Guangzhou Medical University, Institute of Respiratory Diseases, is to organize the rescue, the patient's current condition is still critical.
Zhong Nanshan, patients go to the Institute hosted consultation call
Sent by the provincial health department of the province Huizhou human infection of avian influenza H7N9 clinical expert consultation and assessment, in order to further improve the patient's treatment work, decided to transfer the patient to the First Affiliated Hospital of Guangzhou Institute of Respiratory Diseases treated. 9 at 10 pm, First Affiliated Hospital of Guangzhou Medical University, with a car sent by ambulance carrying patient ventilator leave Huizhou Central People's Hospital, on the 10th morning arrived safely call the Institute. Patient to the hospital immediately after the chest CT, and stay at Critical Care Medicine. 10 morning, academician Zhong Nanshan personally presided over the largest hospital-wide consultation to develop a treatment plan. Call the Institute established a critical care medicine to the Lord, including hospital infection Branch, Department of Radiology, Department of Infectious Diseases, Department of Pharmacy, and other multi-sectoral experts composed of specialized rescue treatment team, working hard to save the patient. Patients are still in critical condition, vital signs were still stable, conscious.
Patients condition:
Cardiopulmonary resuscitation has been severely damaged by four days
Academician Zhong Nanshan, 0:05 yesterday morning, the patient is connected to the Institute by the call of Guangzhou, directly into the ICU, examination revealed sub-type or heavier, had severe pneumonia, also called ARDS (Acute Respiratory Distress Syndrome). Outstanding performance is very low oxygenation index, normal is 300, which is two days of her index two were 80,77, not to 100; Zhong Nanshan team recently concluded 111 cases of human infection of H7N9 avian influenza in patients with oxygenation index, oxygenation index average is 114. "The patient's condition is worse."
First, two ventilation lung function is ventilation, Zhong Nanshan said the patient's ventilatory function is poor, high concentrations of oxygen into the body can not use, indicating that her lung inflammation, fibrosis and other diseases badly, serious virus damage to lungs. Huizhou Central Hospital on the 6th had their endotracheal intubation, and yesterday, the patient has reached four days by artificial respiration.
August 5th, the 7th, the patient appeared twice in Huizhou, heart failure, pulmonary edema and cough up pink frothy sputum. Now look, enzymes liquid ratio is slightly higher, ECG findings of myocardial damage. The patient is conscious, other organs such as brain, muscle, kidney, liver (with elevated transaminases), are very mild damage.
"Parties after treatment, the patient quieter." Zhongyuan Shi concluded.
Close contact situations:
54 has lifted observed 42 remains to be seen
Following the 9th on 36 close contacts under medical observation, the spread of the epidemic for the effective control of the provincial CDC experts and a local disease control departments, in-depth epidemiological investigations, sample collection close contacts to expand the scope of close contacts under medical observation. As at 16:00 on the 10th, a total of 96 close contacts under medical observation, of which 54 have been discharged under medical observation, 42 need to continue medical observation. Patient's son on the evening of August 9, low fever, body temperature 37.8 ℃. 10 morning screening H7N9 was negative, with no fever, chest X-ray and blood examination was normal. Remaining close contacts were abnormal.
Fellow appeal:
Start from the grassroots to use Tamiflu as soon as possible
Zhong Nanshan said that for the first case of the patient's treatment, the current practice is to increase the amount of Tamiflu, the double use of Tamiflu; hand is to continue to timely detect viruses, throat swab or positive, then it will still continue to use Tamiflu if has been positive, the treatment team is ready to use intravenous peramivir, spare but not spend.
Canton Medical a vice president Li Yimin added that in Huizhou Central Hospital, has been used twice the dose of Tamiflu, that neuraminidase inhibitors oseltamivir.
Zhong Nanshan said that the patient is now quite typical of severe H7N9, white blood cell count is low, really heavy condition, future situation, the current can not say, only to go all out. It is contemplated, if patients with Tamiflu few days ago, of course, is better.
Zhong Nanshan, that, first at the grassroots level hospital, July 27 for 3 consecutive days and not for detecting suspicious; followed Huizhou Central Hospital on August 3 a patient received, watching professional background, pneumonia and flu-like symptoms immediately very alert, but can not be detected. This process lasted precisely seven days, very sad. Therefore, Zhong Nanshan, an urgent appeal to have higher primary hospital executive power, watching professional background, pneumonia and influenza-like symptoms should be careful, do not let the timing of early detection and treatment.
Zhong Nanshan Jianfeng answering reporters' questions
Son can not be excluded in patients with H7N9 infection
Reporter: The patient is now able to exclude sick son?
Zhong Nanshan: That will not do, but also repeatedly detect viral nucleic acid job. Another way is 2 to 4 weeks after onset, check H7N9 antibodies.
Jianfeng: Beijing is also found in patients with 2 consecutive check is negative, the 3rd is positive, the 4th and check out is negative.
Reporter: Jiangsu limited human to human cases have occurred, and now his son have a fever, it will increase the risk of human transmission?
Jianfeng: Now there are only limited human to human transmission case, even if the child finally infected patients, it is difficult to determine from person to person, as is common occupational exposure. Now no direct evidence in this regard, but proposed a hypothetical.
One case can not be said virus southward
Reporter: H7N9 avian influenza will occur southward trend in Guangdong will lead to popular?
Zhong Nanshan: Only one case I do not say that, but we are now more cautious. Unless there is a clear genetic mutation, it may lead to (a pandemic), this name is still patient's viral gene sequencing, whether variation is unknown.
Jianfeng: H7N9 epidemic in Guangdong diffusion-human transmission is extremely small or extremely low. The first is currently found or avian origin, there is no human influenza genes, there is no biological basis. Second from epidemiology, 96 Tightlock who 95 are good, only son yesterday appeared in patients with low-grade fever 37.8 ℃, the temperature has been normal now, last night, sampling and testing carried out twice now, have not detected any influenza positive refers to the disease. Currently this is a separate case, there is no diffusion in the crowd.
Reporter: Now the weather is so hot, why there will be cases in Guangdong?
Zhong Nanshan: H7N9 virus at least sixty to seventy degrees Celsius in the environment will (be killed), now how can there be such a high temperature?
Greensboro and the surrounding poultry virus was not detected
County live chicken trade ban for 3 consecutive days
Huizhou newspaper (Reporter correspondent Yan Qin Zhongyang early Xiesi Xiong) yesterday, the reporter saw at Yokogawa market, the market is a row of two layers inside a small building under the chicken stalls have been closed. Yokogawa town grocery market, according to a BOLUO owner, 9 pm, health, quarantine and towns cadres and specialized antivirus fire truck came to the scene to carry out cleaning and disinfection. Market remaining 68 chickens and eight ducks a goose all been concentrated transported destroyed. Someone told reporters: Moumou home chicken stalls poor health, poultry slaughtered in the stalls complete, even the usually one person to eat are also in the stalls.
BOLUO deputy governor Zhu Xiaowen, at present, the incident of suspected problems were all chickens sampled detection, the current bird flu virus is not detected, but these have all been sterilized duck and goose landfill.
Yokogawa markets close for one day for disinfection work, the county will be banned for 3 consecutive days trading of live chickens, especially not marketing field. According to investigation, Chen Moumou chicken stalls mostly from the surrounding towns and villages acquisitions, and some of her own pet.
Currently, relevant departments ongoing investigation chicken sources in the surrounding towns to take a sample of more than 700 cases were detected, yet found the bird flu virus. ILI also conducted local etiological screening to establish timely detection of outbreaks of emergency monitoring system.
Health Department of the urgent deployment of H7N9 prevention and control
Provincial Health Department on August 10 afternoon, held a provincial health system of human infection with H7N9 avian influenza prevention and control of television and telephone conference, to convey and implement the provincial government led by important instructions, deployment prevention and control work.
Chen Yuansheng Minister put forward four requirements: First, we must attach great importance to the epidemic prevention and control work, strengthen organization and leadership. Second, we must continue to strengthen disease surveillance and prevention, focus on key areas, focusing on the prevention and control populations. Third, we should earnestly carry out medical treatment and clinical monitoring. The fourth is to increase health knowledge propaganda, maintain social stability. At the meeting, the provincial CDC director Zhang Yonghui comrades about the epidemic situation, academician Zhong Nanshan explain about the treatment requirements.
Guangzhou to strengthen surveillance of influenza-like illness
WASHINGTON (Reporter Wu Ren) Guangdong first case of human infection of H7N9 found in suspected cases of bird flu. Yesterday, the reporter from the Guangzhou Municipal Center for Disease Control has learned that the health sector will strengthen monitoring efforts to the crowd, in Guangzhou and found no suspected cases of human infection with H7N9.
City CDC deputy director Yang Zhicong introduction, Guangzhou each department has been working on human, avian H7N9 virus and the outer environment daily monitoring suspected cases of human infection occurs in Huizhou, the population of Guangzhou will be a corresponding increase monitoring efforts, such as increased influenza like illness surveillance volume of severe pneumonia, unexplained pneumonia for H7N9 virus detection.
Yang Zhicong reminder, not because of hot weather, relax on H7N9 prevention, and poultry contact protection to do to do, "there is the main argument is that the virus in the winter and spring, fall spread, but I think that this is a new virus, which we did not find out the propagation rule, it can not be taken lightly. "
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