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H1N1 flu must be global before Phase 6 - WHO chief

FrenchieGirl

Senior Moderator
H1N1 flu must be global before Phase 6 - WHO chief

21 May 2009 09:40:58 GMT
Source: Reuters

GENEVA, May 21 (Reuters) - The head of the World Health Organisation said on Thursday she would not hesitate to raise the global pandemic alert to the top of the six-point scale if the H1N1 flu is spreading globally.

"When I see more signals coming from the virus itself or the spread of the disease, including severity, I would not shy away from making a very difficult decision. I would not compromise the world people's health," she said.

"For Phase 5 to Phase 6 I need to satisfy myself that this is a global phenomenon," she told the WHO's annual meeting in Geneva, saying health experts are now monitoring carefully for signs the virus has taken hold in the southern hemisphere. (Reporting by Laura MacInnis)
 
Re: H1N1 flu must be global before Phase 6 - WHO chief

> "When I see more signals coming from the virus itself or the spread
> of the disease, including severity,

so, current severity is not sufficient ?

> I would not shy away from making a very difficult decision.

so, even at that point the decision would be very difficult.
And if the conditions in the previous sentence were not met
(no signals from the virus itself , no more severity)
then she might shy away from making a decision
(and let the expert panel do it instead ?)

> I would not compromise the world people's health," she said.

I can't translate compromise

>"For Phase 5 to Phase 6 I need to satisfy myself that this is a
> global phenomenon," she told the WHO's annual meeting in Geneva,

so, all 5 of the WHO-regions are required now, not 2 ?



WHO has no exclusive authority in calling a pandemic.
In theory we may have a pandemic in future history books without WHO
ever calling it pandemic. And vice versa. WHO may call a pandemic
and then it dies out and WHO withdraws it later ...
 
Re: H1N1 flu must be global before Phase 6 - WHO chief

Apparently she is adding severity and larger geographical spread as additional criteria.
 
Re: H1N1 flu must be global before Phase 6 - WHO chief

> For Phase 5 to Phase 6 I need to satisfy myself that this
> is a global phenomenon,

simultaneously ?

so, assume it dies in America and goes to Asia would that trigger phase 6 ?


and then maybe returns to America in fall or winter ...
compare with 1968, was it "global" at any time ?
 
Re: H1N1 flu must be global before Phase 6 - WHO chief

she is deliberately being unclear ?
 
Re: H1N1 flu must be global before Phase 6 - WHO chief

I do remember the press-conference by Fukuda, last conference
before the big meeting started.

That did sound quite different. WHO doesn't stick to their own
definitions, their own statements ?
 
Re: H1N1 flu must be global before Phase 6 - WHO chief

How much larger of a geographical spread does she need? :rolleyes:



I mean there really isn't that much more of Earth left....
 

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Re: H1N1 flu must be global before Phase 6 - WHO chief

I wrote week or two weeks ago that they are not going to Phase 6 until they absolutely have to - and got pretty much told that they will within few days. All these phases and levels are nice on paper, however when the situation is actually on their only goal is to save as many human lives as possible and at the same time keep the economy running.

Thus until the flu is much severe they will not go to Phase 6, and you can forget what they have said or agreed in the past.

Only way I could see them going to Phase 6 now is if they added some new phase for global super severe pandemic.

There is also the psychological aspect. If they go to Phase 6 now people will just think "look WHO just said its as bad as its gets, we have nothing to worry". There needs to be a way to make sure that people understand how serious the situation can get, media will play important part in that.. however judging by their previous actions I have a feeling that even when its severe they will write about the situation only couple weeks - and again people think the danger is over.

Its a very fine line between avoiding the panic (which would have disastrous effects) and making sure people understand how serious the situation is.

I have now clue how to make that happen in the grand scheme of things. I spoke with my close family members and relatives about the situation and pretty much used the words "Its not bad now so there is no reason to panic, however please prepare by stocking food and making sure you are able to stay indoors for at least few weeks if it gets bad". And im happy to notice that they have paid at least some attention to what I told and have already prepared a bit - though not as much as id hope.

I wonder what would happen if Obama came out and used those words?
 
Re: H1N1 flu must be global before Phase 6 - WHO chief

Since this seems to be turning into a discussion thread, I'll add my 2 cents.

I don't think this is a case of "whatever does she mean by it?"

The problem is probably quite simple: WHO is discovering that the 6-level scale they set up doesn't work very well in the reality they are faced with. They were probably expecting H5N1, where virulence was a given and geographic spread seemed the best measure of the growing threat level. But now we have a flu that is behaving differently, and with only 6 levels at their disposal and all of them dealing with geographical spread, WHO has no place to go if virulence develops later. So they are delaying announcing level 6, which given the circumstances may be the best they can do.

It would make sense to develop a new system based on this experience, but to change now would probably leave a lot of health systems unsure what to do if their action plans are tied to WHO pandemic levels that aren't being used anymore.

As I remember there was quite a good discussion of alternative plans for pandemic threat levels in another thread active about the time we moved to level 5. Maybe somebody can find the link. No time to do that.
 
Re: H1N1 flu must be global before Phase 6 - WHO chief

My only concern with all this remains that a level 6 announcement is a trigger for many countires and organisations within those countries to activate palns. In some cases, this may mean the ordering of additional materials, safety stocks, hospital equipment and heavens knows what else.

If countries (and buisnesses) are behaving as if this really is phase 6 and activating certain preparations regardless of WHO edicts, then I am more comfortable with this, as it is presently a mild outbreak.

However, that can turn on a hairpin. If there is a sudden shift in virulence through activation of the F2 protein for example and people start dying in larger numbers, it will be too late for these last preparatory steps to take place before the world is caught in a mass outbreak.

There are many organisations that put their pandemic plans in place set against the 'old' definitions - and they ahve not revised these since then.

I hope the world does not find itself 'caught short' as a consequence of this.
 
Re: H1N1 flu must be global before Phase 6 - WHO chief

It is pretty clear to me - that to the extent that the Pandemic Levels (1 thru 6) were initially set up to address AVIAN H5N1 - and all activities were therefore based on a potential Pandemic with a 60% CFR.

Since that is not the reality with H1N1 - it is a question now of factoring potential pathogenicity and virulence issues - beyond geographic presentation.

See their own guidelines below as to the following - until this becomes more deadly - they are shying away form the "hottest" level 6.

Please see:

Pathogenicity vs. Virulence


Pathogenicity refers to the ability of an organism to cause disease (ie, harm the host). This ability represents a genetic component of the pathogen and the overt damage done to the host is a property of the host-pathogen interactions. Commensals and opportunistic pathogens lack this inherent ability to cause disease. However, disease is not an inevitable outcome of the host-pathogen interaction and, furthermore, pathogens can express a wide range of virulence.

Virulence, a term often used interchangeably with pathogenicity, refers to the degree of pathology caused by the organism. The extent of the virulence is usually correlated with the ability of the pathogen to multiply within the host and may be affected by other factors (ie, conditional). In summary, an organism (species or strain) is defined as being pathogenic (or not), and depending upon conditions, may exhibit different levels of virulence.



Ed. - THese are the issues that are now being factored in to calling a LEVEL 6 - IMNSOHO (in my not so often humble opinion)
 
Re: H1N1 flu must be global before Phase 6 - WHO chief

IMO, by global, I suspect she means the virus has spread to the heart of the African continent...it isnt there yet.
As far as severity, once we see a substantial number of folks (many with underlying conditions such as AIDS, TB, dengue etc) in the third world dying, then it will go to phase 6. In the west, we have the medical facilities to keep the fatality numbers down...different story in the third world.
 
Re: H1N1 flu must be global before Phase 6 - WHO chief

they should just give and update their panflu-morbidity and mortality
expectation values for the next 12 months !

better than any list of "phases"

also, why not go to phase 5.3 or such, no need to stick to 6 phases,
the more the better
 
Re: H1N1 flu must be global before Phase 6 - WHO chief

they should just give and update their panflu-morbidity and mortality
expectation values for the next 12 months !

better than any list of "phases"

also, why not go to phase 5.3 or such, no need to stick to 6 phases,
the more the better

agreed gsgs - i thought about the same thing - it seems they will have to come up with some quantative scale associated with geo-spread
 
Re: H1N1 flu must be global before Phase 6 - WHO chief

PS - I am not an apologist for this "new" rules of engagement - but from a pragmatic crisis mitigation (economic, social) - I certainly understand it -

It will not mean much to the family's of those that are surely going to expire though as this "continues to creep" - with occasional deaths - even if its virulence remains at present levels.
 
Re: H1N1 flu must be global before Phase 6 - WHO chief

via email -


WHO hesitates over declaring flu pandemic
2009-05-21 12:37:41.712 GMT

by Alexandra Troubnikoff
ATTENTION - ADDS criteria for pandemic six ///

GENEVA, May 21, 2009 (AFP) - A month after the world was alerted
to a potential flu pandemic, the WHO was caught Thursday between
the spread of the new swine flu virus to 41 countries and doubts
fostered by its mild symptoms.

More than 11,000 cases and 85 deaths have been recorded since
the outbreak of A(H1N1) influenza emerged in Mexico and the United
States, and the world remains at flu alert level five, signalling an
"imminent pandemic".

But World Health Organisation Director General Margaret Chan has
stopped short of declaring a fully-fledged pandemic by moving to
phase six, even though travellers have carried it to other
continents.


The top level would indicate sustained community transmission in
a second region outside the Americas.


On Thursday, Japanese Prime Minister Taro Aso appealed for calm
as a total of 281 swine flu cases were reported in the country,
including the first in greater Tokyo, the world's largest urban
area.


Antoine Flahaut, an epidemiologist and head of the School of
Public Health (EHESP) in France, told AFP that the technical
elements were in place to move into the pandemic phase.

"But the WHO senses that recommendations which go with that are
not adapted to the situation," he explained, pointing to air travel
restrictions or advice to wear surgical masks.

"Invoking phase six would be disproportionate with the current
situation."

The doubts have grown because of the relatively mild symptoms of
swine flu, which experts acknowledge is no worse than seasonal
influenza for now.


Many of the deaths have occurred among those who were suffering
from other ailments, a common pattern for ordinary strains of flu.

During a meeting at the WHO's annual assembly Thursday, Chan
listed the issue of swine flu's severity among other criteria that
were prompting caution.

"One of the things we're not seeing is the same spread in the
southern hemisphere that we've seen in the first three countries," a
WHO official added.


When the assembly opened on Monday, British Health Secretary
Alan Johnson voiced doubts about phase six that had been growing
behind the scenes after countries rushed to contain new cases of
swine flu.

Those calls for caution and a more fleixble system prompted nods
of approval from other countries afterwards, including China, Japan
and New Zealand.

"She has taken that on board," WHO spokesman Thomas Abraham
said, underlining that most of the cases in Japan were largely
confined to students or their close entourage.

Chan acknowledged this week that the WHO's pandemic response
plan, introduced nearly four years ago, was largely designed around
the more deadly and virulent, but less transmissible, H5N1 bird flu
virus.

"This scale was based on geographical distribution, but the
public belief is that pandemic means seriousness," said Sylvie
Briand, acting director of the WHO's Global Influenza Program.

But the WHO is also looking ahead at the potential progress of
the new virus, and fears of its impact in poor countries, where
millions of people are already weakened by chronic illness.

"Whatever the member states might say, we are in phase five,"
Abraham remarked.

In studies released by the New England Journal of Medicine,
scientists pointed out the similarities between the new A(H1N1)
virus and ones behind pandemics that marked the 20th century.

Those pandemics in 1918-1919 -- which killed an estimated 50
million people -- in 1957-1963 and 1968-1970 started off as mild but
went through waves that became more lethal at their peak, often the
second season, and had different impacts in different regions.

They also affected young people -- a feature underlined by the
WHO in the current outbreak -- and were highly transmissible, the
researchers from the US National Institutes of Health and George
Washington University said.

Abraham said it was still not clear if young people were more
affected by swine flu because of the nature of the virus, or because
it was more likely to be passed around among students in the close
confines of schools.

"This virus does affect younger people, we don't know the reason
for this - whether it's viral or epidemiological," he explained.
pac/co
 
Re: H1N1 flu must be global before Phase 6 - WHO chief

The term "global" in these international organisations' speech actually means "worldwide".

As for Africa not having H1N1, I don't think there's any real capacity to detect it anywhere there, except perhaps, in one or two labs who can analyse H5N1, and that's if they're looking for H1N1, if they've received diagnostic kits. If there is H1N1 in Africa, one might want to keep an eye on blogs rather than governments themselves. There are many members of world and US charity organisations working in Africa and, no doubt, they travel from their headquarters in North countries to their jobs in South countries. It's probably through them we'll see something.
 
Re: H1N1 flu must be global before Phase 6 - WHO chief

As for Africa not having H1N1, I don't think there's any real capacity to detect it anywhere there, except perhaps, in one or two labs who can analyse H5N1, and that's if they're looking for H1N1, if they've received diagnostic kits. If there is H1N1 in Africa, one might want to keep an eye on blogs rather than governments themselves. There are many members of world and US charity organisations working in Africa and, no doubt, they travel from their headquarters in North countries to their jobs in South countries. It's probably through them we'll see something.

I agree there will be little official information about the spread of A(H1N1) in Africa. It will be the internet detective work of members of FluTrackers and other boards that will most likely identify the first cases of A(H1N1) in Africa based on clinical symptoms.
 
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