tetano
Editor, Senior Moderator
Ocul Immunol Inflamm. 2012 Apr 26. [Epub ahead of print]
H1N1-associated Acute Retinitis.
Rifkin L, Schaal S.
Source
Department of Ophthalmology and Visual Sciences, University of Louisville , 301E Muhammad Ali Blvd, Louisville, KY 40202 , USA.
Abstract
Purpose: To present the first reported case of bilateral H(1)N(1)-associated acute retinitis and its successful treatment. Design: Interventional case report. Methods: A 41-year-old HIV-positive male presented with acute vision loss, panuveitis, and retinitis. A diagnostic and therapeutic vitrectomy with intravitreal injection of vancomycin and ganciclovir and endolaser was performed. One month later, the patient returned with similar symptoms in the fellow eye and underwent the same procedure. Results: ELISA immunoassay revealed H(1)N(1) antibodies in both the vitreous and serum. PCR for herpes viruses included HSV, CMV, and VZV. Bacterial and fungal cultures were negative. On 1-year follow-up, the vision remained 20/20 in both eyes without evidence of recurrent inflammation. Conclusions: H(1)N(1) should be included in the differential diagnosis of any patient with a history of recent influenza A (H(1)N(1)) infection and acute retinitis. H(1)N(1) may carry a better prognosis than other viruses causing acute retinitis.
PMID:
22537287
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/22537287
H1N1-associated Acute Retinitis.
Rifkin L, Schaal S.
Source
Department of Ophthalmology and Visual Sciences, University of Louisville , 301E Muhammad Ali Blvd, Louisville, KY 40202 , USA.
Abstract
Purpose: To present the first reported case of bilateral H(1)N(1)-associated acute retinitis and its successful treatment. Design: Interventional case report. Methods: A 41-year-old HIV-positive male presented with acute vision loss, panuveitis, and retinitis. A diagnostic and therapeutic vitrectomy with intravitreal injection of vancomycin and ganciclovir and endolaser was performed. One month later, the patient returned with similar symptoms in the fellow eye and underwent the same procedure. Results: ELISA immunoassay revealed H(1)N(1) antibodies in both the vitreous and serum. PCR for herpes viruses included HSV, CMV, and VZV. Bacterial and fungal cultures were negative. On 1-year follow-up, the vision remained 20/20 in both eyes without evidence of recurrent inflammation. Conclusions: H(1)N(1) should be included in the differential diagnosis of any patient with a history of recent influenza A (H(1)N(1)) infection and acute retinitis. H(1)N(1) may carry a better prognosis than other viruses causing acute retinitis.
PMID:
22537287
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/22537287