H1N1 and central nervous system lesions in China

[Toaster2]

I found the following story on PFI / sounds like a situation to monitor



H1N1 caused several nerve system lesions in Shenzhen
Published on November 30, 2009 by connie | This story has been viewed 48 times
Among the serious cases of H1N1 flu that are receiving treatment in Shenzhen Municipal Children?s Hospital, there are accumulated nine children who have shown symptoms of pathological changes of nerve system, which have caused great attention of the Health Departments of the State, the Province and the City. The Health Department sampled and researched the pathogenesis of the viral encephalitis occurring on the serious children patients of H1N1 flu.

On the morning of November 29, the 11-year-old boy from Bao?an District, identified as Yuan, who had been in a coma after contracting the A/H1N1 virus, died after half an hour?s rescue by the medical staff, which is the second death from H1N1 flu in Shenzhen.

It?s said that there are several children being treated in Shenzhen Children?s Hospital, of which accumulated 9 have showed symptoms of pathological changes and 6 have been on the way of recovering. Except for the 11-year-old boy Yuan who has just died, another two boys with surname Yang and Tang who have been infected with vital encephalitis are still in deep coma.

According to the introduction of the hospital, the Children?s Hospital received a 3-year-old boy surnamed Chen who has been infected with H1N1 flu days before. The boy?s case was quite serious when coming to the hospital but he had no infection in brain.

According to the introduction, from the H1N1 flu epidemic in China, Shenzhen has the most H1N1 flu children with nerve system lesions. The frequent appearance of the pathological changes of never system has cause great attention of the health department, who have sampled and researched the pathogenesis of the viral encephalitis occurring on the serious children patients of H1N1 flu.

Shenzhen Post Elaine Contributes to the Story.

 

[sharon sanders]

Re: H1N1 and central nervous system lesions in China

Also please see this thread:

Shenzhen- A stream of children with severe encephalitis

http://www.flutrackers.com/forum/showthread.php?t=134763

 

[Marsey]

Re: H1N1 and central nervous system lesions in China

I am interested in this because my mother had encephalitis lethargica, though I understand it never has been proven to be connected to the 1918 pandemic.

 

[Marsey]

Re: H1N1 and central nervous system lesions in China

Interestingly, I did find this:

http://www.pnas.org/content/early/2009/08/07/0900096106.full.pdf+html

 

[AlaskaDenise]

Re: H1N1 and central nervous system lesions in China

Also see:

Lesions of the Central Nervous System Induced in Nonhuman Primates by Live Influenza Viruses

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1319841

Abstract

Intracerebral and intraspinal inoculations of non-neuropathic and neuropathic strains of influenza virus into rhesus, patas and cercopithecus monkeys resulted in an acute focal ependymitis, choroiditis and meningitis followed by focal ependymal denuding without parenchymal involvement. Aqueductal stenosis and moderate hydrocephalus developed in two animals as sequelae of ependymal cell loss.

(full article available at referenced site)

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[AlaskaDenise]

Re: H1N1 and central nervous system lesions in China

The above article is from 1974.

The last portion of the Discussion is:





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