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Genetic Characterization of an Avian Influenza Virus H4N6 Strain Isolated from a Guangxi Pockmark Duck

tetano

Editor, Senior Moderator
Genome Announc. 2017 Aug 24;5(34). pii: e00802-17. doi: 10.1128/genomeA.00802-17.
[h=1]Genetic Characterization of an Avian Influenza Virus H4N6 Strain Isolated from a Guangxi Pockmark Duck.[/h] Xie L[SUP]1[/SUP], Xie Z[SUP]1[/SUP], Wu A[SUP]2[/SUP], Luo S[SUP]2[/SUP], Zhang M[SUP]2[/SUP], Huang L[SUP]2[/SUP], Xie Z[SUP]2[/SUP], Huang J[SUP]2[/SUP], Zhang Y[SUP]2[/SUP], Zeng T[SUP]2[/SUP], Deng X[SUP]2[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] An H4N6 subtype avian influenza virus was isolated from a pockmark duck in southern China in November 2013 and named A/duck/Guangxi/149D24/2013 (H4N6). All eight gene segments of the strain were sequenced. Sequence analysis indicated that this H4N6 virus was a natural reassortant virus. This H4N6 virus has two basic amino acids in the cleavage site of hemagglutinin 1 (HA1) and HA2, and the amino acid motif of cleavage site was PEKASRGLF, which is the typical characteristic of the low-pathogenic avian influenza virus. This study will help understand the epidemiology and molecular characteristics of avian influenza virus in pockmark ducks.
Copyright ? 2017 Xie et al.


PMID: 28839020 DOI: 10.1128/genomeA.00802-17
 
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