Genes from Ebola Virus Family Found in Human Genome

[Emily]

http://www.scientificamerican.com/article/virus-genes-human-genome/

Genes from Ebola Virus Family Found in Human Genome
A rush of new research has found evidence that some RNA viruses made their way into vertebrate genomes millions of years ago
July 30, 2010 |By Katherine Harmon

...

The new findings support a theory of Tufts University School of Medicine molecular biologist John Coffin that viruses in the bornavirus and filovirus groups "are really very old?despite the fact that card-carrying evolutionary biologists have concluded that they must be evolving very rapidly and probably [are] very recent," he says. "That is clearly very wrong." He cites this and other recent work to conclude that some of these hemorrhagic fever viruses have changed little in the course of primate evolution.
...

Unexpected Inheritance: Multiple Integrations of Ancient Bornavirus and Ebolavirus/Marburgvirus Sequences in Vertebrate Genomes
Belyi VA, Levine AJ, Skalka AM (2010) Unexpected Inheritance: Multiple Integrations of Ancient Bornavirus and Ebolavirus/Marburgvirus Sequences in Vertebrate Genomes. PLoS Pathog 6(7): e1001030. doi:10.1371/journal.ppat.1001030

 

[AlaskaDenise]

Re: Genes from Ebola Virus Family Found in Human Genome

http://www.scientificamerican.com/article/virus-genes-human-genome/


Unexpected Inheritance: Multiple Integrations of Ancient Bornavirus and Ebolavirus/Marburgvirus Sequences in Vertebrate Genomes
Belyi VA, Levine AJ, Skalka AM (2010) Unexpected Inheritance: Multiple Integrations of Ancient Bornavirus and Ebolavirus/Marburgvirus Sequences in Vertebrate Genomes. PLoS Pathog 6(7): e1001030. doi:10.1371/journal.ppat.1001030

Yes, Emily - very good paper. EBOV might be one of the "promiscuous pathogens"!

.