Full Genome Sequence of a Natural Reassortant H9N2 Avian Influenza Virus Isolated from Domestic Ducks in Jiangsu Province, China

[tetano]

Genome Announc. 2013 Jul 18;1(4). pii: e00463-13. doi: 10.1128/genomeA.00463-13.
Full Genome Sequence of a Natural Reassortant H9N2 Avian Influenza Virus Isolated from Domestic Ducks in Jiangsu Province, China.
Zhao M, Liu Q, Sun Q, Zhang W, Zhao G, Gu M, Wang X, Hu S, Liu X, Liu X.
Source

Animal Infectious Disease Laboratory, College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, China.
Abstract

In this study, the complete genomic sequence of a novel reassortant H9N2 avian influenza virus (AIV) from domestic ducks in eastern China was reported. Phylogenetic analysis showed that seven of the eight genes were all highly homologous to the chicken-origin H9N2 viruses, whereas the PB2 gene was homologous to the human-origin H1N1 virus, which suggested that domestic ducks might play a key role in the genetic reassortment and evolution of H9N2 AIVs in eastern China.

PMID:
23868123
[PubMed]

Free full text

http://www.ncbi.nlm.nih.gov/pubmed/23868123

 

[gsgs]

Re: Full Genome Sequence of a Natural Reassortant H9N2 Avian Influenza Virus Isolated from Domestic Ducks in Jiangsu Province, China

http://www.ncbi.nlm.nih.gov/nuccore/KF142478

too close to 1918-flu to be credible

....

and indeed, close to the 1934 lab-strain --> likely contamination


ahh, they even noticed this:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715665/

but didn't get the idea of possible contamination ?!?




Full Genome Sequence of a Natural Reassortant H9N2 Avian Influenza Virus Isolated from
Domestic Ducks in Jiangsu Province, China

> which suggested that domestic ducks might play a key role in the genetic reassortment
> and evolution of H9N2 AIVs in eastern China.

in that case - if true - I'd say flu researchers play a key role in the genetic reassortment
and evolution of influenza

as in 1976

 

[gsgs]

Re: Full Genome Sequence of a Natural Reassortant H9N2 Avian Influenza Virus Isolated from Domestic Ducks in Jiangsu Province, China

I think they should remove such sequences from genbank.
Or move them to a special,separate list
It causes much confusion in all the BLAST-searches, phylo-trees
and mutation tables.


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this one
http://www.ncbi.nlm.nih.gov/nuccore/KF142478
has human segment 1 from 1934


http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715665/

In this study, the complete genomic sequence of a novel reassortant H9N2 avian influenza virus (AIV) from domestic ducks in eastern China was reported. Phylogenetic analysis showed that seven of the eight genes were all highly homologous to the chicken-origin H9N2 viruses, whereas the PB2 gene was homologous to the human-origin H1N1 virus, which suggested that domestic ducks might play a key role in the genetic reassortment and evolution of H9N2 AIVs in eastern China.

The BLAST and phylogenetic analyses of the Dk1 genomic sequence demonstrated that the PB2 gene shared the highest homology (above 99%) with that of a human-origin strain, A/Puerto Rico/8/1934(H1N1), while the other seven genes had the greatest sequence identities (99% to 100%) with a chicken-origin strain, A/Chicken/Shanghai/F/98(H9N2).