tetano
Editor, Senior Moderator
Front Vet Sci
. 2023 Feb 23;10:1111728.
doi: 10.3389/fvets.2023.1111728. eCollection 2023.
SARS-CoV-2 antibodies in dogs and cats in a highly infected area of Brazil during the pandemic
Samar Afif Jarrah[SUP] 1 [/SUP], Louise Bach Kmetiuk[SUP] 2 [/SUP], Fabrizia Valleriani[SUP] 3 [/SUP], Barbara Bonfini[SUP] 3 [/SUP], Alessio Lorusso[SUP] 3 [/SUP], Violetta Vasinioti[SUP] 4 [/SUP], Nicola Decaro[SUP] 4 [/SUP], Marco Tulio Dos Santos[SUP] 1 [/SUP], Kledir Anderson Hofstaetter Spohr[SUP] 1 [/SUP], Annamaria Pratelli[SUP] 4 [/SUP], Anna Serroni[SUP] 3 [/SUP], Sara Capista[SUP] 3 [/SUP], Valéria Regia Franco Sousa[SUP] 1 [/SUP], Alexander Welker Biondo[SUP] 2 [/SUP], Luciano Nakazato[SUP] 1 [/SUP], Valéria Dutra[SUP] 1 [/SUP]
Affiliations
Abstract
SARS-CoV-2 was a worldwide threat during the COVID-19 pandemic, and the state of Mato Grosso had the second highest mortality rate in Brazil, with 427. 4 deaths/100,000 inhabitants. However, no large-scale study among dogs and cats in such highly infected areas of Brazil has so far been conducted. Accordingly, the present study reports on a serosurvey among dogs and cats in Cuiabá, capital of Mato Grosso from November 2020 to July 2021, where the human mortality rate was 605/100,000 at that time. Overall, 33/762 dogs (4.3%) and 4/182 cats (2.2%) were found to be seropositive for SARS-CoV-2 through ELISA, and 3/762 dogs (0.4%) and 3/182 cats (1.6%) were seropositive through the serum neutralization test. Cats presented higher seroprevalence with higher titers of neutralizing antibodies. Although N-protein based ELISA may be a good screening test, cross-reactivity with other canine coronaviruses may impair its diagnostic use among dogs.
Keywords: Brazil; SARS-CoV-2; companion animals; coronavirus; pets; serosurvey.
. 2023 Feb 23;10:1111728.
doi: 10.3389/fvets.2023.1111728. eCollection 2023.
SARS-CoV-2 antibodies in dogs and cats in a highly infected area of Brazil during the pandemic
Samar Afif Jarrah[SUP] 1 [/SUP], Louise Bach Kmetiuk[SUP] 2 [/SUP], Fabrizia Valleriani[SUP] 3 [/SUP], Barbara Bonfini[SUP] 3 [/SUP], Alessio Lorusso[SUP] 3 [/SUP], Violetta Vasinioti[SUP] 4 [/SUP], Nicola Decaro[SUP] 4 [/SUP], Marco Tulio Dos Santos[SUP] 1 [/SUP], Kledir Anderson Hofstaetter Spohr[SUP] 1 [/SUP], Annamaria Pratelli[SUP] 4 [/SUP], Anna Serroni[SUP] 3 [/SUP], Sara Capista[SUP] 3 [/SUP], Valéria Regia Franco Sousa[SUP] 1 [/SUP], Alexander Welker Biondo[SUP] 2 [/SUP], Luciano Nakazato[SUP] 1 [/SUP], Valéria Dutra[SUP] 1 [/SUP]
Affiliations
- PMID: 36908526
- PMCID: PMC9995883
- DOI: 10.3389/fvets.2023.1111728
Abstract
SARS-CoV-2 was a worldwide threat during the COVID-19 pandemic, and the state of Mato Grosso had the second highest mortality rate in Brazil, with 427. 4 deaths/100,000 inhabitants. However, no large-scale study among dogs and cats in such highly infected areas of Brazil has so far been conducted. Accordingly, the present study reports on a serosurvey among dogs and cats in Cuiabá, capital of Mato Grosso from November 2020 to July 2021, where the human mortality rate was 605/100,000 at that time. Overall, 33/762 dogs (4.3%) and 4/182 cats (2.2%) were found to be seropositive for SARS-CoV-2 through ELISA, and 3/762 dogs (0.4%) and 3/182 cats (1.6%) were seropositive through the serum neutralization test. Cats presented higher seroprevalence with higher titers of neutralizing antibodies. Although N-protein based ELISA may be a good screening test, cross-reactivity with other canine coronaviruses may impair its diagnostic use among dogs.
Keywords: Brazil; SARS-CoV-2; companion animals; coronavirus; pets; serosurvey.