tetano
Editor, Senior Moderator
Front Med (Lausanne)
. 2021 Dec 16;8:698268.
doi: 10.3389/fmed.2021.698268. eCollection 2021.
Bilateral Spontaneous Pneumothorax in a COVID-19 and HIV-Positive Patient: A Case Report
Young Min Cho[SUP] 1 [/SUP], Sara Guevara[SUP] 2 [/SUP], Judith Aronsohn[SUP] 3 4 [/SUP], James M Mumford[SUP] 4 5 [/SUP], Linda Shore-Lesserson[SUP] 3 4 [/SUP], Santiago J Miyara[SUP] 6 7 [/SUP], Martin Herrera[SUP] 1 [/SUP], Claudia Kirsch[SUP] 4 [/SUP], Christine N Metz[SUP] 4 6 7 [/SUP], Stefanos Zafeiropoulos[SUP] 6 7 [/SUP], Dimitrios Giannis[SUP] 7 [/SUP], Alexia McCann-Molmenti[SUP] 8 [/SUP], Kei Hayashida[SUP] 7 8 [/SUP], Koichiro Shinozaki[SUP] 7 8 [/SUP], Muhammad Shoaib[SUP] 4 7 [/SUP], Rishabh C Choudhary[SUP] 7 8 [/SUP], Gabriel I Aranalde[SUP] 2 [/SUP], Lance B Becker[SUP] 4 6 7 8 [/SUP], Ernesto P Molmenti[SUP] 4 6 7 [/SUP], James Kruer[SUP] 1 [/SUP], Anthony Hatoum[SUP] 1 [/SUP]
Affiliations
Abstract
This case report describes a 60 year-old Black-American male with a past medical history of human immunodeficiency virus (HIV) infection and hyperthyroidism, who suffered a bilateral spontaneous pneumothorax (SP) in the setting of coronavirus disease 2019 (COVID-19) pneumonia. SP is a well-established complication in HIV-positive patients and only recently has been associated with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. While HIV and COVID-19 infections have been independently linked with increased risk of SP development, it is unknown if both infections interact in a synergistic fashion to exacerbate SP risk. According to the Centers for Disease Control and Prevention (CDC), patients living with HIV have a higher risk of developing severe COVID-19 infection and the mechanism remains to be elucidated. To the best of our knowledge, this is the first report of a HIV-positive patient, who in the setting of SARS-CoV-2 infection, developed bilateral apical spontaneous pneumothorax and was later found to have a left lower lobe tension pneumothorax. This case highlights the importance of considering SP on the differential diagnosis when HIV-positive patients suddenly develop respiratory distress in the setting of SARS-CoV-2 infection.
Keywords: COVID-19; HAART; HIV/AIDS; SARS-CoV-2; bilateral pneumothorax; spontaneous pneumothorax; tension pneumothorax.
. 2021 Dec 16;8:698268.
doi: 10.3389/fmed.2021.698268. eCollection 2021.
Bilateral Spontaneous Pneumothorax in a COVID-19 and HIV-Positive Patient: A Case Report
Young Min Cho[SUP] 1 [/SUP], Sara Guevara[SUP] 2 [/SUP], Judith Aronsohn[SUP] 3 4 [/SUP], James M Mumford[SUP] 4 5 [/SUP], Linda Shore-Lesserson[SUP] 3 4 [/SUP], Santiago J Miyara[SUP] 6 7 [/SUP], Martin Herrera[SUP] 1 [/SUP], Claudia Kirsch[SUP] 4 [/SUP], Christine N Metz[SUP] 4 6 7 [/SUP], Stefanos Zafeiropoulos[SUP] 6 7 [/SUP], Dimitrios Giannis[SUP] 7 [/SUP], Alexia McCann-Molmenti[SUP] 8 [/SUP], Kei Hayashida[SUP] 7 8 [/SUP], Koichiro Shinozaki[SUP] 7 8 [/SUP], Muhammad Shoaib[SUP] 4 7 [/SUP], Rishabh C Choudhary[SUP] 7 8 [/SUP], Gabriel I Aranalde[SUP] 2 [/SUP], Lance B Becker[SUP] 4 6 7 8 [/SUP], Ernesto P Molmenti[SUP] 4 6 7 [/SUP], James Kruer[SUP] 1 [/SUP], Anthony Hatoum[SUP] 1 [/SUP]
Affiliations
- PMID: 34977051
- PMCID: PMC8716636
- DOI: 10.3389/fmed.2021.698268
Abstract
This case report describes a 60 year-old Black-American male with a past medical history of human immunodeficiency virus (HIV) infection and hyperthyroidism, who suffered a bilateral spontaneous pneumothorax (SP) in the setting of coronavirus disease 2019 (COVID-19) pneumonia. SP is a well-established complication in HIV-positive patients and only recently has been associated with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. While HIV and COVID-19 infections have been independently linked with increased risk of SP development, it is unknown if both infections interact in a synergistic fashion to exacerbate SP risk. According to the Centers for Disease Control and Prevention (CDC), patients living with HIV have a higher risk of developing severe COVID-19 infection and the mechanism remains to be elucidated. To the best of our knowledge, this is the first report of a HIV-positive patient, who in the setting of SARS-CoV-2 infection, developed bilateral apical spontaneous pneumothorax and was later found to have a left lower lobe tension pneumothorax. This case highlights the importance of considering SP on the differential diagnosis when HIV-positive patients suddenly develop respiratory distress in the setting of SARS-CoV-2 infection.
Keywords: COVID-19; HAART; HIV/AIDS; SARS-CoV-2; bilateral pneumothorax; spontaneous pneumothorax; tension pneumothorax.