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flu.org.cn - weekly newsletter

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flu.org.cn newsletter: News

Singapore, Indonesia battle avian flu together (AFP)
SINGAPORE (AFP) - Singapore and Indonesia on Wednesday agreed to carry out a pilot project aimed at boosting Jakarta in its battle with the deadly bird ...
submitted by pub4world at May, 10, 2007 1:53 AM via(http://us.rd.yahoo.com/dailynews/rs....com/s/afp/20070509/hl_afp/healthflusingapore)

Togo bans Ghana poultry following bird flu discovery (AFP)
LOME (AFP) - Togo banned poultry from neighbouring Ghana on Wednesday after a case of the deadly H5N1 bird flu was detected there, the agriculture ministry ...
submitted by kickingbird at May, 10, 2007 1:53 AM via(http://us.rd.yahoo.com/dailynews/rs....com/s/afp/20070509/hl_afp/togoghanahealthflu)

Bird flu not only pandemic risk, US experts warn
By Julie Steenhuysen CHICAGO, May 8 (Reuters) - While many health experts see the H5N1 bird flu virus as a likely cause for an influenza pandemic, another ...
submitted by 2366 at May, 9, 2007 7:13 AM via(http://www.alertnet.org/thenews/newsdesk/N08198788.htm)

Indonesia to press bird flu case at WHO (AFP)
JAKARTA (AFP) - Indonesia will urge World Health Organisation members to scrap the existing international policy on bird flu samples when the body meets ...
submitted by wanglh at May, 8, 2007 19:45 PM via(http://us.rd.yahoo.com/dailynews/rs...m/s/afp/20070508/hl_afp/indonesiahealthfluwho)

Clark School "e;Virus Sponge"e; Could Improve Flu Treatments, Diabetes Care, Vaccine Development (U.S. Newswire)
To: EDUCATION EDITORSContact: Missy Corley, +1-301-405-6501, Cell: +1-804-398-8652, mcorley@umd.edu, or Lee Tune, +1-301-405-4679, ltune@umd.edu, both ...
submitted by 2366 at May, 8, 2007 19:22 PM via(http://us.rd.yahoo.com/dailynews/rs...reatments__diabetes_care__vaccine_development)

India tests chickens for bird flu after deaths
KOLKATA, India, May 8 (Reuters) - Indian authorities were testing dead poultry for bird flu in an eastern state after more than 3,000 birds were found ...
submitted by pub4world at May, 8, 2007 17:12 PM via(http://www.alertnet.org/thenews/newsdesk/DEL224573.htm)

Masks may not help against super-flu
If a flu pandemic strikes, face masks may not protect you. Even so, the government says people should consider wearing them in certain situations, just ...
submitted by kickingbird at May, 8, 2007 11:19 AM via(http://english.peopledaily.com.cn/200705/08/eng20070508_372826.html)

France cuts bird flu risk level, says threat falls
PARIS, May 7 (Reuters) - France has reduced its precautions against bird flu as the risk of the disease hitting the country has become negligible again, ...
submitted by kickingbird at May, 7, 2007 19:33 PM via(http://www.alertnet.org/thenews/newsdesk/L07558014.htm)

Indonesian woman dies of bird flu -health ministry
(Adds details) JAKARTA, May 7 (Reuters) - An Indonesian woman from Sumatra has died from bird flu, a health ministry official said on Monday, taking the ...
submitted by 2366 at May, 7, 2007 17:21 PM via(http://www.alertnet.org/thenews/newsdesk/SP233038.htm)

29-YEAR-OLD INDONESIAN WOMAN HAS DIED FROM BIRD FLU - HEALTH MIN
29-YEAR-OLD INDONESIAN WOMAN HAS DIED FROM BIRD FLU - HEALTH MINISTRY OFFICIAL
submitted by 2366 at May, 7, 2007 16:38 PM via(http://www.alertnet.org/thenews/newsdesk/JAK200750.htm)

Bird flu re-emerges in central Vietnam, kills ducks
HANOI, May 6 (Reuters) - Bird flu has been found on a duck farm in central Vietnam, the first outbreak of the disease in more than a month, the government ...
submitted by pub4world at May, 6, 2007 13:5 PM via(http://www.alertnet.org/thenews/newsdesk/HAN196291.htm)

Avian Flu 'Supermap' Yields New Info On Source/spread
Scientists here have designed a new, interactive map of the spread of the avian flu virus (H5N1) that for the first time incorporates genetic, geographic ...
submitted by kickingbird at May, 6, 2007 5:12 AM via(http://www.medicalnewstoday.com/medicalnews.php?newsid=69497&nfid=crss)

U.S. says to reduce bird flu testing during '07 (Reuters)
WASHINGTON (Reuters) - The United States will test fewerwild birds during 2007 for the avian influenza virus than itdid a year ago, but government officials ...
submitted by kickingbird at May, 5, 2007 5:39 AM via(http://us.rd.yahoo.com/dailynews/rs...om/s/nm/20070504/hl_nm/birdflu_testing_usa_dc)

ANX-201 Drug Combination Demonstrates Synergistic Activity Against Human And Bird Flu Viruses
rate this articleADVENTRX Pharmaceuticals, Inc. (Amex: ANX), a biopharmaceutical research and development company focused on commercializing proprietary ...
submitted by 2366 at May, 4, 2007 15:25 PM via(http://www.medicalnewstoday.com/medicalnews.php?newsid=69822&nfid=crss)

TFAH Calls For Stockpiling Of Masks To Meet Medical Requirements To Prepare For The Threat Of Pandemic Flu
rate this articleTrust for America"e;s Health (TFAH) supports the interim guidance issued today in Mortality and Morbidity Weekly Report concerning ...
submitted by pub4world at May, 4, 2007 15:25 PM via(http://www.medicalnewstoday.com/medicalnews.php?newsid=69826&nfid=crss)

Novavax Reports Positive Pre-Clinical Study Results From Live Virus Challenge To Pandemic Flu Vaccine
rate this articleNovavax Inc. said today that it has received positive study results from a live virus challenge to ferrets inoculated with its pandemic ...
submitted by kickingbird at May, 4, 2007 15:24 PM via(http://www.medicalnewstoday.com/medicalnews.php?newsid=69827&nfid=crss)

U.S.: HHS Issues Interim Guidance for the Use of Facemasks and Respirators in Public Settings During an Influenza Pandemic
HHS Issues Interim Guidance for the Use of Facemasks and Respirators in Public Settings During an Influenza Pandemic Facemasks and Respirators Could Provide ...
submitted by kickingbird at May, 4, 2007 9:8 AM via(http://www.hhs.gov/news/press/2007pres/05/pr20070503a.html)

Article

Recombinant Modified Vaccinia Virus Ankara-Based Vaccine Induces Protective Immunity in Mice against Infection with Influenza Virus H5N1
Since 2003, the number of human cases of infections with highly pathogenic avian influenza viruses of the H5N1 subtype is still increasing, and, therefore, ...
submitted by kickingbird at May, 9, 2007 17:28 PM via(http://www.ncbi.nlm.nih.gov/entrez/...ve&db=PubMed&list_uids=17471429&dopt=Abstract)

Design and Validation of an H5 TaqMan Real-Time One-Step Reverse Transcription-PCR and Confirmatory Assays for Diagnosis and Verification of Influenza A Virus H5 Infections in Humans.
Increasing diversity among influenza H5N1 viruses has resulted in the need for sensitive and specific diagnostic assays, fully validated for the detection ...
submitted by kickingbird at May, 9, 2007 17:26 PM via(http://www.ncbi.nlm.nih.gov/entrez/...ve&db=PubMed&list_uids=17473050&dopt=Abstract)

Determining risk factors for infection with influenza A (H5N1) [letter]
To the Editor: Novel antigenic subtypes of influenza viruses have been introduced periodically into the human population, resulting in large-scale global ...
submitted by kickingbird at May, 4, 2007 9:6 AM via(http://www.cdc.gov/eid/content/13/6/pdfs/07-0025.pdf)

Loop-mediated Isothermal Amplification for Influenza A (H5N1) Virus
We describe a 1-step reverse-transcription loop-mediated isothermal amplification assay for detection of highly pathogenic avian influenza A (H5N1) viruses. ...
submitted by kickingbird at May, 4, 2007 9:4 AM via(http://www.cdc.gov/eid/content/13/6/pdfs/06-1572.pdf)

--Flu In China & Flu Information Centre
May, 10, 2007 8:40 AM

--------------------------------------------------------------------
Our E-mail content is utf-8 format,if you can not read it, please change your E-mail client encode setting or ask for on-line help in http://www.flu.org.cn/en/contact.html
 
Last edited by a moderator:
Re: FIC

Re: FIC

http://magictour.free.fr/fict1.html

(I can't post html here)


-----------------------------------

in
http://www.medicalnewstoday.com/medicalnews.php?newsid=75267&nfid=crss
Corrie Brown said :

>Whether the bird flu virus will spread to North America is unpredictable at this time

but here they are predicting it:
http://fluprediction.uiowa.edu/fluhome/AvianFlu_Graphical.cfm?type=policy#humanLocation
http://www.intrade.com/jsp/intrade/common/c_cd.jsp?conDetailID=425334&z=1183012132376

>Although the likelihood of this mutation is unlikely, history cautions us to the possibility.

an unlikely likelyhood ? That's an unlikelyhood then ;-)

>The longer the bird flu virus is in circulation, the greater the risk for a pandemic.

most experts see it vice versa. ("if it hadn't gone pandemic yet, it might not be capable")

>Unfortunately, we are poorly prepared for other emerging infectious diseases, and it's
>difficult to predict where the next pathogen will come from, or when.
>Our challenge: expect the unexpected

nonsense. Contradiction in itself.
-------------------------------------------------
 
Last edited:
Re: FIC

Re: FIC

Phenotypic properties resulting from directed gene segment reassortment between wild-type A/Sydney/5/97 influenza virus and the live attenuated vaccine strain
Widespread use of a live-attenuated influenza vaccine (LAIV) in the United States (licensed as FluMist) raises the possibility that vaccine viruses will ...
submitted by kickingbird at Jul, 12, 2007 8:32 AM via(http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=17599381&dopt=Abstract)

Dynamics of antigenic and genetic changes in the hemagglutinins of influenza A/H3N2 viruses of three consecutive seasons (2002/2003 to 2004/2005) in Austria
Human influenza viruses are subject to continuous antigenic drift and this phenomenon poses great problems for the annual production of vaccines which ...
submitted by kickingbird at Jul, 12, 2007 8:31 AM via(http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=17601639&dopt=Abstract)

Increased immunogenicity of influenza virus vaccine by anti-Gal mediated targeting to antigen presenting cells
This study describes a method for increasing immunogenicity of influenza virus vaccines by exploiting the natural anti-Gal antibody for effective targeting ...
submitted by kickingbird at Jul, 12, 2007 8:29 AM via(http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=17609270&dopt=Abstract)

Longer virus shedding in influenza B than in influenza A among outpatients treated with oseltamivir
OBJECTIVE: To compare the persistence, susceptibility and resistance of influenza A and influenza B viruses in oseltamivir therapy in outpatients of various ...
submitted by kickingbird at Jul, 12, 2007 8:27 AM via(http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=17604839&dopt=Abstract)

Infection prevention and control of epidemic- and pandemic-prone acute respiratory diseases in health care
WHO/CDS/EPR/2007.6 WHO Interim Guidelines June 2007Full text (English)- [pdf 2.68Mb] Guidance updates The present guidelines supersede the document ...
submitted by kickingbird at Jul, 11, 2007 8:57 AM via(http://www.who.int/csr/resources/publications/WHO_CD_EPR_2007_6/en/index.html)



http://magictour.free.fr/fic1.html
 
Re: FIC

Re: FIC

> Overall, no reassortant strains were more virulent than wild-type,
> and in fact, 33 of the 34 recombinant viruses replicated less
> efficiently in infected ferrets. These results suggest that
> genetic reassortment between wild and vaccine strains is unlikely
> to produce viruses having novel properties that differ substantially
> from either progenitor, and that the likely outcome of reassortment
> will be attenuated viruses.

well, the likely outcome from mutations are generally in average less
viable viruses, still selection filters the viable ones.

Could we attenuate H5N1 by creating a new flu-virus and
inoculating it into waterfowl, waiting for reassortments
which will then be cultivated and replicated and improved etc. ?

Sort of virus "breeding" in order to create viruses which are
less dangerous but more contagious and will compete with wild-viruses,
hopefully replacing them as a pandemic virus destroys pre-existing
flu.

We cannot controll mutation, but we can somehow control reassortment
by manipulated double-infections.
 
Re: FIC

Re: FIC

this comes weekly, I'd appreciate if we could post it here in this
thread each week.
I can try, but may not be able each week...


--------------------------------------------------------------------------

flu.org.cn newsletter
News
WHO: Avian influenza-situation in Viet Nam
28 December 2007 The Ministry of Health in Viet Nam has confirmed a new case of human infection of H5N1 avian influenza. The case has been confirmed by ...
submitted by kickingbird at Dec, 29, 2007 8:46 AM via
http://www.who.int/csr/don/2007_12_28/en/index.html

WHO: Avian influenza-situation in Egypt-update
28 December 2007 The Ministry of Health and Population, Egypt has announced two new cases of human infection of H5N1 avian influenza. The first case ...
submitted by kickingbird at Dec, 29, 2007 8:46 AM via
http://www.who.int/csr/don/2007_12_28a/en/index.html

No sign of bird flu mutation after Pakistani dies: WHO (AFP)
GENEVA (AFP) - The World Health Organisation on Friday ruled out any mutation of the potentially fatal H5N1 strain of the bird flu virus after a case of ...
submitted by kickingbird at Dec, 29, 2007 3:4 AM via
http://news.yahoo.com/s/afp/20071228/hl_afp/healthflupakistanwho

WHO confirms H5N1 case in Pakistan cluster
Dec 27, 2007 (CIDRAP News) – The World Health Organization (WHO) today announced its first confirmation of a human case of H5N1 avian influenza in Pakistan, ...
submitted by kickingbird at Dec, 28, 2007 8:29 AM via
link

WHO: Avian influenza-situation in Pakistan-update
27 December 2007 The first case of human infection with H5N1 avian influenza has been confirmed in Pakistan. Laboratory tests conducted by the WHO H5 ...
submitted by kickingbird at Dec, 28, 2007 8:22 AM via
http://www.who.int/csr/don/2007_12_27/en/index.html

Two Egyptians test positive for bird flu (Reuters)
CAIRO (Reuters) - Two Egyptians have tested positive forthe deadly H5N1 bird flu virus, a day after an Egyptian womandied of the disease, Egypt's health ...
submitted by kickingbird at Dec, 28, 2007 3:0 AM via
http://news.yahoo.com/s/nm/20071227/hl_nm/birdflu_egypt_dc

Study: flu shots may protect against bird flu
Special report: Global fight against bird flu BEIJING, Dec. 27 (Xinhuanet) -- A recent study supports a theory that seasonal flu ...
submitted by 2366 at Dec, 27, 2007 17:48 PM via
http://news.xinhuanet.com/english/2007-12/27/content_7324251.htm

WHO: Avian influenza-situation in Egypt
26 December 2007 The Ministry of Health and Population, Egypt has announced a new case of human infection of H5N1 avian influenza.. The case is a 25 ...
submitted by kickingbird at Dec, 27, 2007 10:14 AM via
http://www.who.int/csr/don/2007_12_26a/en/index.html

WHO: Avian influenza-situation in Indonesia-update 28
26 December 2007 The Ministry of Health of Indonesia has announced a new case of human infection of H5N1 avian influenza. A 24-year-old female from West ...
submitted by kickingbird at Dec, 27, 2007 10:14 AM via
http://www.who.int/csr/don/2007_12_26/en/index.html

Regular flu vaccine may help against H5N1: study (Reuters)
WASHINGTON (Reuters) - Ordinary seasonal flu vaccines mayprovide a small amount of protection against bird flu, Italianresearchers reported on Wednesday. ...
submitted by kickingbird at Dec, 27, 2007 2:10 AM via
http://news.yahoo.com/s/nm/20071226/hl_nm/birdflu_vaccine_dc

Egyptian woman dies of bird flu (Reuters)
CAIRO (Reuters) - A 25-year-old Egyptian woman has died ofbird flu, Egypt's Ministry of Health said on Wednesday. It is the first human death in Egypt ...
submitted by kickingbird at Dec, 26, 2007 22:11 PM via
http://news.yahoo.com/s/nm/20071226/hl_nm/birdflu_egypt_dc

German chicken tests positive for H5N1 flu strain (Reuters)
BERLIN (Reuters) - A third case of a chicken testingpositive for the deadly H5N1 bird flu virus in the northeastGerman state of Brandenburg was confirmed ...
submitted by kickingbird at Dec, 26, 2007 21:26 PM via
http://news.yahoo.com/s/nm/20071226/sc_nm/birdflu_germany_dc

Bird flu death rises to 94 in Indonesia
Special report: Global fight against bird flu BEIJING, Dec. 26 (Xinhuanet) -- An Indonesian woman died Tuesday from bird flu, raising ...
submitted by 2366 at Dec, 26, 2007 14:37 PM via
http://news.xinhuanet.com/english/2007-12/26/content_7315819.htm

Indonesian woman dies from bird flu (Reuters)
JAKARTA (Reuters) - An Indonesian woman who bought a livechicken from a market died from bird flu on Christmas Day, theHealth Ministry bird flu centre ...
submitted by 2366 at Dec, 26, 2007 11:47 AM via
http://news.yahoo.com/s/nm/20071226/hl_nm/birdflu_indonesia_dc

Vietnam suspects bird flu killed young child (Reuters)
HANOI (Reuters) - Doctors suspect bird flu may have killeda four-year-old child in northern Vietnam, state-run radio saidon Wednesday. A Health Ministry ...
submitted by wanglh at Dec, 26, 2007 9:59 AM via
http://news.yahoo.com/s/nm/20071226/hl_nm/birdflu_vietnam_death_dc

Indonesian woman dies from bird flu, total to 94
A 24-year-old Indonesian woman from West Jakarta has died from avian influenza, putting the total fatalities in the country to 94, the ...
submitted by kickingbird at Dec, 26, 2007 8:17 AM via
http://news.xinhuanet.com/english/2007-12/25/content_7312656.htm

China reports good progress in human bird flu vaccine (AFP)
BEIJING (AFP) - China has made good progress in developing a human vaccine against the deadly bird flu virus, with a second phase of tests showing it ...
submitted by 2366 at Dec, 25, 2007 1:20 AM via
http://news.yahoo.com/s/afp/20071224/hl_afp/healthchinafluvaccine

Published human H5N1 Nucleotide sequences in China from Genebank
DQ371928 1704 Human 4 (HA) H5N1 China 2005 Influenza A virus (A/Anhui/1/2005(H5N1)) DQ371929 1704 Human 4 (HA) H5N1 China 2005 Influenza ...
submitted by kickingbird at Dec, 24, 2007 21:22 PM via
http://www.ncbi.nlm.nih.gov/genomes/FLU/

Published human H5N1 protein sequences in China from GeneBank
ABD28180 567 Human 4 (HA) H5N1 China 2005 Influenza A virus (A/Anhui/1/2005(H5N1)) ABD28181 567 Human 4 (HA) H5N1 China 2005 Influenza ...
submitted by kickingbird at Dec, 24, 2007 21:18 PM via
http://www.ncbi.nlm.nih.gov/genomes/FLU

OIE: Low pathogenic avian influenza (poultry), Dominican Republic
Information received on 21/12/2007 from Dra Gomez Lissette, punto focal OIE, Dirección General de Ganader?*a, Departamento de Sanidad Animal, SANTO DOMINGO, ...
submitted by kickingbird at Dec, 24, 2007 20:57 PM via
http://www.oie.int

Pakistan still probing human transmission in bird flu: ministry (AFP)
ISLAMABAD (AFP) - Pakistan's health ministry said it was still investigating whether there was human transmission in the country's first death ...
submitted by 2366 at Dec, 24, 2007 16:58 PM via
http://news.yahoo.com/s/afp/20071224/wl_sthasia_afp/healthflupakistan

Polish government says new H5N1 flu confirmed (AFP)
WARSAW (AFP) - A new outbreak of the potentially lethal H5N1 avian flu has been detected in northern Poland where cases have already been reported, the ...
submitted by 2366 at Dec, 23, 2007 4:24 AM via
http://news.yahoo.com/s/afp/20071222/hl_afp/polandhealthavianflu

WHO investigates bird flu in Pakistan (AP)
HANOI, Vietnam - Limited human-to-human bird flu transmission may have occurred in Pakistan, but no new infections have been reported for two weeks and ...
submitted by pub4world at Dec, 22, 2007 14:43 PM via
http://news.yahoo.com/s/ap/20071222/ap_on_re_as/asia_bird_flu



Article


Human infections associated with wild birds
Summary Introduction Wild birds and especially migratory species can become long-distance vectors for a wide range of microorganisms. The objective ...
submitted by kickingbird at Dec, 29, 2007 8:43 AM via
http://www.journalofinfection.com/article/PIIS0163445307008122/abstract

Experimental Infection of Swans and Geese with Highly Pathogenic Avian Influenza Virus (H5N1) of Asian Lineage
The role of wild birds in the epidemiology of the Asian lineage highly pathogenic avian influenza (HPAI) virus subtype H5N1 epizootic and their contribution ...
submitted by kickingbird at Dec, 25, 2007 9:26 AM via
http://www.cdc.gov/eid/content/14/1/136.htm

Avian Influenza Virus (H5N1) Replication in Feathers of Domestic Waterfowl
We examined feathers of domestic ducks and geese inoculated with 2 different avian influenza virus (H5N1) genotypes. Together with virus isolation from ...
submitted by kickingbird at Dec, 25, 2007 9:24 AM via
http://www.cdc.gov/eid/content/14/1/149.htm

Cross-subtype Immunity against Avian Influenza in Persons Recently Vaccinated for Influenza
Avian influenza virus (H5N1) can be transmitted to humans, resulting in a severe or fatal disease. The aim of this study was to evaluate the immune cross-reactivity ...
submitted by kickingbird at Dec, 25, 2007 9:22 AM via
http://www.cdc.gov/eid/content/14/1/121.htm

Highly conserved regions of the influenza A virus polymerase gene segments are critical for efficient vRNA packaging
The genome of the Influenza A virus is composed of eight different segments of negative sense RNA. These eight segments are incorporated into budding virions ...
submitted by kickingbird at Dec, 24, 2007 21:40 PM via
link

Molecular analysis of avian H7 influenza viruses circulating in Eurasia in 1999 2005: detection of multiple reassortant virus genotypes
Avian influenza infections by high and low pathogenicity H7 influenza viruses have caused several outbreaks in European poultry in recent years, also resulting ...
submitted by kickingbird at Dec, 24, 2007 21:39 PM via
link

Novel reassortant of swine influenza H1N2 virus in Germany
European porcine H1N2 influenza viruses arose after multiple reassortment steps involving a porcine influenza virus with avian-influenza-like internal ...
submitted by kickingbird at Dec, 24, 2007 21:38 PM via
link

--Flu In China & Flu Information Centre
Dec, 29, 2007 9:31 AM
--------------------------------------------------------------------
Our E-mail content is utf-8 format,if you can not read it, please change your E-mail client encode setting or ask for on-line help in http://www.flu.org.cn/en/contact.html
 
flu.org.cn - weekly newsletter

I'll post here the weekly FIC (flu-in-China) newsletters with processed links,
I hope the links work with this software.
You can also see their webpage :
http://www.flu.org.cn/en/
(with pictures, slowly loading for me)
One new thread per week, discussion as replies (?)


-----------------------------------------------------------------


flu.org.cn newsletter , 2008/March/11


News
Pandemic flu plan would put Chicago on lockdown (Reuters)
CHICAGO (Reuters) - Containing an influenza pandemic in alarge U.S. city like Chicago would require widespread schoolclosings, quarantines of infected ...
submitted by kickingbird at Mar, 11, 2008 5:33 AM via
http://news.yahoo.com/s/nm/20080310/us_nm/birdflu_containment_dc

India culls poultry to contain new bird flu outbreak (Reuters)
NEW DELHI (Reuters) - Only a month after authoritiesdeclared bird flu was under control in eastern India,veterinary workers began culling thousands of ...
submitted by 2366 at Mar, 10, 2008 18:9 PM via
http://news.yahoo.com/s/nm/20080310/hl_nm/birdflu_india_dc

Japan to make vaccines for multiple strains of flu (Reuters)
TOKYO (Reuters) - A group of Japanese researchers hasdeveloped a substance that could help make flu vaccineseffective for multiple strains of the disease, ...
submitted by pub4world at Mar, 10, 2008 18:9 PM via
http://news.yahoo.com/s/nm/20080310/hl_nm/influenza_dc

Japan eyes all-round bird flu vaccine (AFP)
TOKYO (AFP) - Japanese researchers said Monday they had paved the way to develop an all-round vaccine to protect people from bird flu and its feared mutations. ...
submitted by wanglh at Mar, 10, 2008 14:33 PM via
http://news.yahoo.com/s/afp/20080310/hl_afp/healthflujapanvaccine

India: Bird flu back in Bengal villages
Fresh cases of bird flu have been detected in two Murshidabad villages, weeks after the Bengal government said culling operations were over and lifted ...
submitted by kickingbird at Mar, 10, 2008 11:47 AM via
http://www.telegraphindia.com/1080309/jsp/frontpage/story_8998363.jsp

Egyptian boy confirmed with bird flu, 47th case
An 8-year-old boy in Fayoum province has contracted the bird flu virus after coming into contact with infected birds -- the 47th case among humans in Egypt ...
submitted by kickingbird at Mar, 9, 2008 10:33 AM via
http://www.alertnet.org/thenews/newsdesk/L087754.htm

VietNam: Hanoi reports bird flu outbreak
Northern Vietnam is seeing a massive outspread of bird flu epidemic as eight out of the 12 provinces and city hit by the epidemic nationwide are in the ...
submitted by kickingbird at Mar, 9, 2008 10:32 AM via
http://www.thanhniennews.com/healthy/?catid=8&newsid=36481

China: Dead bird found in HK tests positive for H5N1
An oriental magpie robin found dead earlier in Hong Kong has tested positive for the deadly H5N1 strain of the bird flu virus, ...
submitted by kickingbird at Mar, 9, 2008 10:30 AM via
http://news.xinhuanet.com/english/2008-03/08/content_7743471.htm

Hong Kong holds avian flu drill
Special report: Global fight against bird flu HONG KONG, March 7 (Xinhua) -- More than 300 people from government departments, the ...
submitted by wanglh at Mar, 7, 2008 18:33 PM via
http://news.xinhuanet.com/english/2008-03/07/content_7740477.htm

WHO: Avian influenza-situation in Egypt-update 6
5 March 2008 The Ministry of Health and Population of Egypt has announced a new human case of avian influenza A(H5N1) virus infection. The case is an ...
submitted by kickingbird at Mar, 7, 2008 8:13 AM via
http://www.who.int/csr/don/2008_03_05/en/index.html

No sign of deadly mutation in Indonesian bird flu samples: WHO (AFP)
JAKARTA (AFP) - Bird flu samples sent by the Indonesian government to the World Health Organisation show no sign the virus has mutated into a deadly form ...
submitted by kickingbird at Mar, 6, 2008 22:47 PM via
http://news.yahoo.com/s/afp/20080306/wl_asia_afp/healthfluindonesiawho

Bird flu well entrenched in Asia: WHO (AFP)
MANILA (AFP) - The bird flu virus is "firmly entrenched" in Asia and a pandemic among humans remains possible, a World Health Organization (WHO) ...
submitted by kickingbird at Mar, 5, 2008 15:5 PM via
http://news.yahoo.com/s/afp/20080305/wl_asia_afp/healthfluasiawho

WHO: Avian influenza-situation in Egypt-update 5
4 March 2008 The Ministry of Health and Population of Egypt has announced a new human case of avian influenza A(H5N1) virus infection. The case is a 25 ...
submitted by kickingbird at Mar, 5, 2008 8:47 AM via
http://www.who.int/csr/don/2008_03_04/en/index.html

Egyptian woman dies of bird flu, 20th in country (Reuters)
CAIRO (Reuters) - An Egyptian woman aged 25 has died ofbird flu, the 20th death in Egypt from the disease since thevirus arrived in the country in early ...
submitted by 2366 at Mar, 5, 2008 8:12 AM via
http://news.yahoo.com/s/nm/20080304/hl_nm/birdflu_egypt_dc

Woman dies of bird flu in Egypt (AFP)
CAIRO (AFP) - A young Egyptian woman has died of bird flu, becoming the 20th victim of the deadly virus in Egypt over the past two years, the health ministry ...
submitted by pub4world at Mar, 5, 2008 8:12 AM via
http://news.yahoo.com/s/afp/20080304/hl_afp/healthfluegypt



Article


Virulence of H5N1 avian influenza virus enhanced by a 15-nucleotide deletion in the viral nonstructural gene
More and more H5N1 subtype avian influenza viruses possessing a 15-nucleotide (15-nt) deletion in the viral nonstructural protein (NS) gene from position ...
submitted by kickingbird at Mar, 9, 2008 11:23 AM via
link

Proposed lead molecules against Hemagglutinin of avian influenza virus (H5N1).
Human infection with avian influenza H5N1 is an emerging infectious disease characterized by respiratory symptoms and a high fatality rate. Hemagglutinin ...
submitted by kickingbird at Mar, 9, 2008 11:22 AM via
link

Evaluation of antigen detection kits for diagnosis of equine influenza
In this study, we evaluated whether five rapid antigen detection kits for human influenza could be used for the diagnosis of equine influenza (EI). Limiting ...
submitted by kickingbird at Mar, 9, 2008 11:20 AM via
link

The pathology of bronchointerstitial pneumonia in young foals associated with the first outbreak of equine influenza in Australia
Reasons for performing study: The first outbreak of equine influenza virus (EIV) infection was confirmed in Australia in 2007. Some EIV-positive young ...
submitted by kickingbird at Mar, 9, 2008 11:20 AM via
link

Natural selection for nucleotide usage at synonymous and non-synonymous sites in the influenza A genes
Influenza A is one of the best studied viruses and a model organism for the study of molecular evolution; in particular, much research has focused on detecting ...
submitted by kickingbird at Mar, 9, 2008 11:19 AM via
link

Realtime RT-PCR Assay Unable to Detect H7 Subtype Avian Influenza Viruses Isolated from Wild Birds
We report a failure of the current real-time RT-PCR H7 subtyping protocol, used in national avian influenza surveillance programs. Significant substitutions ...
submitted by kickingbird at Mar, 9, 2008 11:17 AM via
link

Influenza A virus neuraminidase limits viral superinfection.
Enveloped viruses use multiple mechanisms to inhibit infection of a target cell by more than one virion. These mechanisms may be of particular importance ...
submitted by kickingbird at Mar, 9, 2008 11:16 AM via
link

The evolution of human influenza A viruses from 1999 to 2006 - a complete genome study
ABSTRACT: BACKGROUND: Knowledge about the complete genome constellation of seasonal influenza A viruses from different countries is valuable for the monitoring ...
submitted by kickingbird at Mar, 9, 2008 11:15 AM via
link

Rescinding community mitigation strategies in an influenza pandemic
Using a networked, agent-based computational model of a stylized community, we evaluated thresholds for rescinding 2 community mitigation strategies after ...
submitted by kickingbird at Mar, 9, 2008 11:14 AM via
link

Protective effect of maritime quarantine in South pacific jurisdictions, 1918-19 influenza pandemic
We reviewed mortality data of the 1918-19 influenza pandemic for 11 South Pacific Island jurisdictions. Four of these appear to have successfully delayed ...
submitted by kickingbird at Mar, 9, 2008 11:13 AM via
link

Transmission of equine influenza virus to english foxhounds
We retrospectively demonstrated that an outbreak of severe respiratory disease in a pack of English foxhounds in the United Kingdom in September 2002 was ...
submitted by kickingbird at Mar, 9, 2008 11:12 AM via
link

Low Frequency of Infection with Avian Influenza Virus (H5N1) among Poultry Farmers, Thailand, 2004
In Thai provinces where avian influenza outbreaks in poultry had been confirmed in the preceding 6 months, serum from 322 poultry farmers was tested for ...
submitted by kickingbird at Mar, 9, 2008 11:11 AM via
link

Mutations in Influenza A Virus (H5N1) and Possible Limited Spread, Turkey, 2006
We report mutations in influenza A virus (H5N1) strains associated with 2 outbreaks in Turkey. Four novel amino acid changes (Q447L, N556K, and R46K in ...
submitted by kickingbird at Mar, 9, 2008 11:11 AM via
link

Highly Pathogenic Avian Influenza Virus (H5N1) in Domestic Poultry and Relationship with Migratory Birds, South Korea
During the 2006-2007 winter season in South Korea, several outbreaks of highly pathogenic avian influenza virus (H5N1) were confirmed among domestic poultry ...
submitted by kickingbird at Mar, 9, 2008 11:10 AM via
link

Influenza-related hospitalisation and death in Australians aged 50 years and older.
Estimating the true burden of influenza is problematic because relatively few hospitalisations or deaths are specifically coded as influenza related. Statistical ...
submitted by kickingbird at Mar, 9, 2008 11:9 AM via
link

Detection and isolation of H5N1 influenza virus from large volumes of natural water
Various species of aquatic or wetlands birds can be the natural reservoir of avian influenza A viruses of all hemagglutinin (HA) subtypes. Shedding of ...
submitted by kickingbird at Mar, 9, 2008 11:8 AM via
link

Clinical and genetic characterization of severe influenza B-associated diseases during an outbreak in Taiwan
BACKGROUND: Mismatches between circulating and vaccine strains of influenza virus had been observed in Taiwan. A comprehensive clinical and genetic analysis ...
submitted by kickingbird at Mar, 9, 2008 11:7 AM via
link

RESEARCH ON THE DIFFERENCE OF HA1 REGION BETWEEN ISOLATION STRAINS AND VACCINE STRAINS OF INFLUENZA VIRUSES SUBTYPE A1 IN JIANGXI PROVINCE FROM 2005 TO 2006
Objective To analyze the difference of HA1 region between isolation strains and vaccine strains of influenza viruses subtype A1 in Jiangxi province from ...
submitted by kickingbird at Mar, 9, 2008 11:4 AM via
http://www.cnki.net

Detection of aian influenza virus-infected cells by flow cytometry
MDCK cells,which were infected by H4 subtype avian influenza virus with different diluted concentration were cultured in the culture medium containing ...
submitted by kickingbird at Mar, 9, 2008 11:3 AM via
http://www.cnki.net

Research on the plaque forming features and pathogenicity of H5N1 avian influenza virus strains isolated from human
Objective To observe the plaque forming characteristics of different H5N1 avian influenza virus strains.And contrast the differences of pathogenicity and ...
submitted by kickingbird at Mar, 9, 2008 11:1 AM via
http://www.cnki.net

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Mar, 11, 2008 9:21 AM
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18.Mar.2008

18.Mar.2008

News



Vietnamese child dies from bird flu
Vietnam's National Hygiene and Epidemiology Institute said the country's latest human case of bird flu infection was a 11-year-old boy from northern Ha ...
submitted by kickingbird at Mar, 17, 2008 17:59 PM via
http://news.xinhuanet.com/english/2008-03/17/content_7807393.htm

China confirms outbreak of bird flu in Guangdong Province
HONG KONG - Chinese officials have confirmed that bird flu was to blame for killing chickens in poultry markets in the southern Chinese city of Guangzhou, ...
submitted by 2366 at Mar, 16, 2008 21:58 PM via
http://news.yahoo.com/s/ap/20080316/ap_on_he_me/china_bird_flu

China: Update on influenza situation in Hong Kong (13th, March)
The Centre for Health Protection (CHP) of the Department of Health (DH) today (March 13) followed up on 50 new reports of influenza-like illness ( ILI ...
submitted by kickingbird at Mar, 14, 2008 16:46 PM via
http://www.chp.gov.hk/view_content.asp?lang=en&info_id=11669

VietNam: Owston’s palm civets in national park die of bird flu
From February 2 to March 2, six Owston’s palm civets, two common plam civets, five pee-wit hoopie birds, two langurs and one loris have died. Independent ...
submitted by kickingbird at Mar, 13, 2008 16:59 PM via
http://english.vietnamnet.vn/social/2008/03/772984/

China: Update on institutional outbreaks of influenza in Hong Kong
The Centre for Health Protection (CHP) of the Department of Health (DH) received reports of influenza-like illness (ILI) outbreaks affecting 23 schools ...
submitted by kickingbird at Mar, 13, 2008 16:55 PM via
http://www.chp.gov.hk/view_content.asp?lang=en&info_id=11652

No pain as Japan develops nasal spray bird flu vaccine (AFP)
TOKYO (AFP) - Japanese researchers said Wednesday they were in the final stage of developing a painless bird flu vaccine which is sprayed up the nose instead ...
submitted by kickingbird at Mar, 13, 2008 0:21 AM via
http://news.yahoo.com/s/afp/20080312/hl_afp/healthflujapanvaccine

China: Hong Kong dead bird tested for H5 virus
A sick peregrine falcon found in Ma Wan has tested positive in a preliminary examination for H5 avian flu, the Agriculture, Fisheries & Conservation Department ...
submitted by kickingbird at Mar, 12, 2008 9:25 AM via
link

India conducts night raids to contain bird flu (Reuters)
NEW DELHI (Reuters) - Authorities in India's east battlingto contain a fresh outbreak of bird flu said they were raidingfarms at night to catch chickens ...
submitted by pub4world at Mar, 11, 2008 20:56 PM via
http://news.yahoo.com/s/nm/20080311/sc_nm/birdflu_india_dc

Bird flu showing signs of mutation: China expert (Reuters)
HONG KONG (Reuters) - One of China's top doctors hasdisclosed that the H5N1 bird flu virus has shown signs ofmutation and can kill human victims more ...
submitted by pub4world at Mar, 11, 2008 11:54 AM via
http://news.yahoo.com/s/nm/20080311/hl_nm/birdflu_china_hongkong_dc



Article


Ethical planning for an influenza pandemic
A U.K. Pandemic Influenza Contingency Plan was developed in 2006 but little research has since been carried out as to how ethically acceptable it will ...
submitted by kickingbird at Mar, 18, 2008 8:42 AM via
link

Mitigation measures for pandemic influenza in Italy: an individual based model considering different scenarios
BACKGROUND: Individual-based models can provide the most reliable estimates of the spread of infectious diseases. In the present study, we evaluated the ...
submitted by kickingbird at Mar, 18, 2008 8:42 AM via
http://www.plosone.org/article/info:doi/10.1371/journal.pone.0001790

A new influenza virus virulence determinant: The NS1 protein four C-terminal residues modulate pathogenicity
The virulence of influenza virus is a multigenic trait. One determinant of virulence is the multifunctional NS1 protein that functions in several ways ...
submitted by kickingbird at Mar, 18, 2008 8:39 AM via
http://www.pnas.org/cgi/reprint/0800482105v1

Mx1 causes resistance against influenza A viruses in the Mus spretus-derived inbred mouse strain SPRET/Ei
Inbred SPRET/Ei mice, derived from Mus spretus, were found to be extremely resistant to infection with a mouse adapted influenza A virus. The resistance ...
submitted by kickingbird at Mar, 18, 2008 8:38 AM via
link

Modeling targeted layered containment of an influenza pandemic in the United States
Planning a response to an outbreak of a pandemic strain of influenza is a high public health priority. Three research groups using different individual-based, ...
submitted by kickingbird at Mar, 18, 2008 8:37 AM via
http://www.pnas.org/cgi/reprint/0706849105v1

Identification of amino acids in the HA of H3 influenza viruses that determine infectivity levels in primary swine respiratory epithelial cells
In the late 1990s, triple reassortant H3N2 influenza A viruses emerged and spread widely within the swine population of the United States. We have shown ...
submitted by kickingbird at Mar, 18, 2008 8:36 AM via
link

Influenza virus and proteolytic bacteria co-infection in respiratory tract from individuals presenting respiratory manifestations
A role for proteolytic bacteria in the exacerbation of influenza virus has been shown in natural hosts such as pigs and humans. Four hundred seven samples ...
submitted by kickingbird at Mar, 18, 2008 8:35 AM via
link

Concerns, Perceived Impact and Preparedness in an Avian Influenza Pandemic - a Comparative Study between Healthcare Workers in Primary and Tertiary Care
Introduction: With the potential threat of an avian influenza (AI) pandemic, healthcare workers (HCWs) are expected to play important roles, and they encounter ...
submitted by kickingbird at Mar, 18, 2008 8:33 AM via
link

Clinical and genetic characterization of severe influenza B-associated diseases during an outbreak in Taiwan
BACKGROUND: Mismatches between circulating and vaccine strains of influenza virus had been observed in Taiwan. A comprehensive clinical and genetic analysis ...
submitted by kickingbird at Mar, 18, 2008 8:32 AM via
link

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Mar, 18, 2008 8:55 AM
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News


Indian state begins fresh bird flu cull (AFP)
KOLKATA (AFP) - Health workers in India's West Bengal state have begun culling poultry after a fresh outbreak of deadly bird flu, officials said. Blood ...
submitted by wanglh at Mar, 23, 2008 16:3 PM via
http://news.yahoo.com/s/afp/20080321/wl_sthasia_afp/healthfluindia

Booster patch helps bird flu vaccine: study (Reuters)
WASHINGTON (Reuters) - A skin patch helped boost a bird fluvaccine so well that people appear to be protected by a singledose, researchers at biotechnolgy ...
submitted by wanglh at Mar, 21, 2008 0:9 AM via
http://news.yahoo.com/s/nm/20080320/sc_nm/birdflu_patch_dc

India expands culling zone to contain bird flu (Reuters)
KOLKATA, India (Reuters) - Veterinary staff in safety gearbegan killing thousands of chickens on Thursday after expandinga culling operation to stop bird ...
submitted by wanglh at Mar, 20, 2008 23:48 PM via
http://news.yahoo.com/s/nm/20080320/hl_nm/india_birdflu_dc

India culls chickens to stop bird flu spreading (Reuters)
KOLKATA (Reuters) - Authorities in eastern India onWednesday started culling thousands of chickens, fearing thespread of bird flu in another district after ...
submitted by pub4world at Mar, 20, 2008 2:5 AM via
http://news.yahoo.com/s/nm/20080319/hl_nm/india_birdflu_dc

UN: Indonesia failing in bird flu fight (AP)
JAKARTA, Indonesia - Efforts to contain bird flu are failing in Indonesia, increasing the possibility that the virus may mutate into a deadlier form, the ...
submitted by 2366 at Mar, 19, 2008 15:5 PM via
http://news.yahoo.com/s/ap/20080319/ap_on_he_me/indonesia_bird_flu

Indonesia: Avian, human flu coinfection reported in teenager
An Indonesian teenager has been brought forward as a case of simultaneous infection with seasonal and avian strains of influenza—a possibility that health ...
submitted by kickingbird at Mar, 19, 2008 9:53 AM via
link

WHO: Avian influenza-situation in Viet Nam-update 5
The Ministry of Health in Viet Nam has confirmed a new case of human infection of H5N1 avian influenza. The case has been confirmed by the National Institute ...
submitted by kickingbird at Mar, 19, 2008 8:53 AM via
http://www.who.int/csr/don/2008_03_18/en/index.html

OIE: Highly pathogenic avian influenza, Turkey
Information received on 18/03/2008 from Assoc Prof Dr Muzaffer Aydemir, Director General, General Directorate of Protection and Control, Ministry of Agriculture ...
submitted by kickingbird at Mar, 19, 2008 8:18 AM via
http://www.oie.int

Bird flu in Indonesia could mutate into human form: UN agency (AFP)
ROME (AFP) - The bird flu situation is "critical" in Indonesia, where the virus could mutate and cause a human pandemic, the UN food agency warned ...
submitted by kickingbird at Mar, 19, 2008 0:43 AM via
http://news.yahoo.com/s/afp/20080318/hl_afp/healthfluindonesiafao

Bird flu may mutate to human form in Indonesia: FAO (Reuters)
MILAN (Reuters) - The bird flu virus, widespread inIndonesia, could mutate and cause a human influenza pandemic,the United Nations' Food and Agriculture ...
submitted by wanglh at Mar, 18, 2008 22:55 PM via
http://news.yahoo.com/s/nm/20080318/hl_nm/bird_flu_dc

China: Experts of Hong Kong, Macao and Guangdong meet to discuss seasonal flu
Public health and medical professional of Hong Kong, Macao and Guangdong today (March 17) held a meeting at the Centre for Health Protection (CHP) of the ...
submitted by kickingbird at Mar, 18, 2008 14:40 PM via
http://www.chp.gov.hk/view_content.asp?lang=en&info_id=11741

Vietnam military to test bird flu vaccine on humans (Reuters)
HANOI (Reuters) - Vietnam, one of the countries hardest-hit by bird flu, will start a human vaccine trial this month, amilitary medical official said ...
submitted by 2366 at Mar, 18, 2008 13:35 PM via
http://news.yahoo.com/s/nm/20080318/hl_nm/birdflu_vietnam_vaccine_dc



Article


Structural basis for the function and inhibition of an influenza virus proton channel
The M2 protein from influenza A virus is a pH-activated proton channel that mediates acidification of the interior of viral particles entrapped in endosomes. ...
submitted by kickingbird at Mar, 25, 2008 8:52 AM via
http://www.nature.com/nature/journal/v451/n7178/abs/nature06528.html

Morpholino oligomers targeting the PB1 and NP genes enhance the survival of mice infected with highly pathogenic influenza A H7N7 virus
Peptide-conjugated phosphorodiamidate morpholino oligomers (PPMO) are single-stranded nucleic acid-analogue antisense agents that enter cells readily and ...
submitted by kickingbird at Mar, 25, 2008 8:50 AM via
http://vir.sgmjournals.org/cgi/content/abstract/89/4/939

Ecology of H3 avian influenza viruses in Korea and assessment of their pathogenic potentials
To determine the genetic origins of novel H3 avian influenza viruses of chickens and ducks in Korea, genetic characterization of H3 avian influenza viruses ...
submitted by kickingbird at Mar, 25, 2008 8:48 AM via
http://vir.sgmjournals.org/cgi/content/abstract/89/4/949

Protection of cats against lethal influenza H5N1 challenge infection
Highly pathogenic avian influenza virus (HPAIV) H5N1 of Asian origin continues to circulate in poultry and wild birds, causing considerable concern for ...
submitted by kickingbird at Mar, 25, 2008 8:45 AM via
http://vir.sgmjournals.org/cgi/content/abstract/89/4/968

Identification of human-to-human transmissibility factors in PB2 proteins of influenza A by large-scale mutual information analysis
BACKGROUND: The identification of mutations that confer unique properties to a pathogen, such as host range, is of fundamental importance in the fight ...
submitted by kickingbird at Mar, 25, 2008 8:43 AM via
http://www.biomedcentral.com/1471-2105/9/S1/S18

Comparative phyloinformatics of virus genes at micro and macro levels in a distributed computing environment
BACKGROUND: Preparedness for a possible global pandemic caused by viruses such as the highly pathogenic influenza A subtype H5N1 has become a global priority. ...
submitted by kickingbird at Mar, 25, 2008 8:42 AM via
http://www.biomedcentral.com/1471-2105/9/S1/S23

Rule-based knowledge aggregation for large-scale protein sequence analysis of influenza A viruses
BACKGROUND: The explosive growth of biological data provides opportunities for new statistical and comparative analyses of large information sets, such ...
submitted by kickingbird at Mar, 25, 2008 8:40 AM via
http://www.biomedcentral.com/1471-2105/9/S1/S7

Population-wide emergence of antiviral resistance during pandemic influenza
BACKGROUND: The emergence of neuraminidase inhibitor resistance has raised concerns about the prudent use of antiviral drugs in response to the next influenza ...
submitted by kickingbird at Mar, 25, 2008 8:38 AM via
http://www.plosone.org/article/info:doi/10.1371/journal.pone.0001839

Origin of the 1918 Spanish influenza virus: A comparative genomic analysis.
To test the avian-origin hypothesis of the 1918 Spanish influenza virus we surveyed influenza sequences from a broad taxonomic distribution and collected ...
submitted by kickingbird at Mar, 25, 2008 8:37 AM via
link

Simultaneous genotyping of all hemagglutinin and neuraminidase subtypes of avian influenza viruses using padlock probes
A subtyping assay for both the hemagglutinin (HA) and neuraminidase (NA) surface antigens of the Avian Influenza virus (AIV) has been developed. The method ...
submitted by kickingbird at Mar, 25, 2008 8:34 AM via
http://jcm.asm.org/cgi/content/abstract/JCM.02292-07v1

Homologous Recombination is Very Rare or Absent in Human Influenza A Virus
To determine the extent of homologous recombination in human influenza A virus we assembled a data set of 13,852 sequences representing all eight segments ...
submitted by kickingbird at Mar, 25, 2008 8:32 AM via
http://jvi.asm.org/cgi/content/abstract/JVI.02683-07v1

Differential response of respiratory dendritic cell subsets to influenza virus infection
Dendritic cells (DC) are believed to play an important role in the initiation of innate and adaptive immune responses to infection - including respiratory ...
submitted by kickingbird at Mar, 25, 2008 8:30 AM via
http://jvi.asm.org/cgi/content/abstract/JVI.02367-07v1

Cross-recognition of avian H5N1 influenza virus by human cytotoxic T lymphocyte populations directed to human influenza A virus
Since the number of human cases of infection with avian H5N1 influenza viruses is ever increasing, a pandemic outbreak caused by these viruses is feared. ...
submitted by kickingbird at Mar, 25, 2008 8:29 AM via
http://jvi.asm.org/cgi/content/abstract/JVI.02694-07v1

Protection against Influenza A Virus by Memory CD8 T Cells Requires Reactivation by Bone Marrow-Derived Dendritic Cells
Influenza A virus is the causative agent of an acute inflammatory disease of the airway. Although Abs can prevent infection, disease and death can be prevented ...
submitted by kickingbird at Mar, 25, 2008 8:27 AM via
http://www.jimmunol.org/cgi/content/abstract/180/7/4956

Infectivity Studies of Influenza Virus Hemagglutinin Receptor Binding-Site Mutants in Mice
The replicative properties of influenza hemagglutinin (HA) mutants with altered receptor binding characteristics were analyzed following intranasal inoculation ...
submitted by kickingbird at Mar, 25, 2008 8:25 AM via
http://jvi.asm.org/cgi/content/abstract/JVI.01958-07v1

Antibody contributes to heterosubtypic protection against influenza A-induced tachypnea in cotton rats.
Influenza virus infection or vaccination evokes an antibody response to viral hemagglutinin (HA) and neuraminidase (NA) surface glycoproteins, which ...
submitted by kickingbird at Mar, 25, 2008 8:23 AM via
http://www.virologyj.com/content/5/1/44

A study quantifying the hand-to-face contact rate and its potential application to predicting respiratory tract infection.
A substantial portion of human respiratory tract infection is thought to be transmitted via contaminated hand contact with the mouth, eyes, and/or nostrils. ...
submitted by kickingbird at Mar, 25, 2008 8:21 AM via
http://www.informaworld.com/smpp/content?content=10.1080/15459620802003896

Identification of the progenitors of Indonesian and Vietnamese avian influenza A (H5N1) viruses from southern China
The transmission of highly pathogenic avian influenza H5N1 virus to Southeast Asian countries triggered the first major outbreak and transmission wave ...
submitted by kickingbird at Mar, 19, 2008 12:58 PM via
http://www.ncbi.nlm.nih.gov/pubmed/18216109?ordinalpos=1

Molecular survey of avian respiratory pathogens in commercial broiler chicken flocks with respiratory diseases in jordan
Acute respiratory tract infections are of paramount importance in the poultry industry. Avian influenza virus (AIV), infectious bronchitis virus (IBV), ...
submitted by kickingbird at Mar, 19, 2008 9:44 AM via
http://www.ncbi.nlm.nih.gov/pubmed/18281569?dopt=Abstract

Hydrophobic Inactivation of Influenza Viruses confers Preservation of Viral Structure with Enhanced Immunogenicity
The use of inactivated influenza virus for the development of vaccines with broad heterosubtypic protection requires selective inactivation techniques ...
submitted by kickingbird at Mar, 19, 2008 9:41 AM via
http://www.ncbi.nlm.nih.gov/pubmed/18305038?dopt=Abstract

Interaction of Polymerase Subunit PB2 and NP with Importin alpha1 Is a Determinant of Host Range of Influenza A Virus
We have previously reported that mutations in the polymerase proteins PB1, PB2, PA, and the nucleocapsid protein NP resulting in enhanced transcription ...
submitted by kickingbird at Mar, 19, 2008 9:40 AM via
http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.0040011

Quantitative biochemical rationale for differences in transmissibility of 1918 pandemic influenza A viruses
The human adaptation of influenza A viruses is critically governed by the binding specificity of the viral surface hemagglutinin (HA) to long (chain length) ...
submitted by kickingbird at Mar, 19, 2008 9:38 AM via
http://www.pnas.org/cgi/content/full/105/8/2800

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Mar, 25, 2008 9:5 AM
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News


S.Korea reports bird flu outbreak, culls poultry (Reuters)
SEOUL (Reuters) - South Korea has started culling over300,000 chickens and other poultry after confirming an outbreakof highly virulent bird flu at a farm ...
submitted by wanglh at Apr, 4, 2008 9:13 AM via(
http://news.yahoo.com/s/nm/20080404/sc_nm/birdflu_korea_dc

China approves bird flu vaccine for humans (Reuters)
HONG KONG (Reuters) - Beijing has given the go-ahead to aChinese drug maker to begin large-scale production of a humanbird flu vaccine, after a second ...
submitted by kickingbird at Apr, 3, 2008 14:14 PM via(
http://news.yahoo.com/s/nm/20080403/hl_nm/birdflu_china_vaccine_dc

Vietnam starts human trials for bird flu vaccine (Reuters)
HANOI (Reuters) - Vietnam has started clinical trials fordeveloping a human vaccine for the H5N1 virus, researchers saidon Thursday in the Southeast ...
submitted by kickingbird at Apr, 3, 2008 14:14 PM via(
http://news.yahoo.com/s/nm/20080403/hl_nm/birdflu_vietnam_vaccine_dc

Dogs catch flu directly from birds, study finds (Reuters)
WASHINGTON (Reuters) - Dogs can catch influenza directlyfrom birds, Korean researchers said on Wednesday, saying theirfinding shows pets could play a ...
submitted by kickingbird at Apr, 3, 2008 8:32 AM via(
http://news.yahoo.com/s/nm/20080402/hl_nm/birdflu_dogs_dc

Indonesian child tests positive for bird flu (Reuters)
JAKARTA (Reuters) - An Indonesian child has tested positivefor bird flu, pushing the country's total confirmed human casesto 130, a health ministry ...
submitted by kickingbird at Apr, 1, 2008 6:38 AM via(
http://news.yahoo.com/s/nm/20080331/hl_nm/birdflu_indonesia_dc

UN links ducks, people, rice paddies for bird flu (AFP)
ROME (AFP) - Concentrations of ducks, rice paddies and people are primarily responsible for outbreaks of potentially deadly bird flu across Asia, the UN ...
submitted by kickingbird at Mar, 29, 2008 7:6 AM via(
http://news.yahoo.com/s/afp/20080326/hl_afp/healthfluunfao

Study finds key factors behind bird flu outbreaks (Reuters)
WASHINGTON (Reuters) - Ducks, people and rice paddies arethe primary forces driving outbreaks of avian influenza inThailand and Vietnam, and the number ...
submitted by wanglh at Mar, 29, 2008 7:6 AM via(
http://news.yahoo.com/s/nm/20080326/hl_nm/birdflu_outbreaks_dc

Bird flu hits staple of Egypt"e;s streets (AP)
TAWFIQIYA, Egypt - Chickens used to roam every dusty street in every village across Egypt, and many of its city alleys too. But bird flu is changing that. ...
submitted by kickingbird at Mar, 29, 2008 7:6 AM via(
http://news.yahoo.com/s/ap/20080326/ap_on_re_mi_ea/egypt_bird_flu

Swiss report first bird flu case in 2 years (Reuters)
ZURICH (Reuters) - Switzerland reported the first case ofH5N1 bird flu in the country in two years in a duck onSempachersee lake, veterinary authorities ...
submitted by pub4world at Mar, 29, 2008 7:6 AM via(
http://news.yahoo.com/s/nm/20080327/hl_nm/swiss_birdflu_dc

Indonesia limits sharing of bird flu samples (Reuters)
JAKARTA (Reuters) - Indonesia will not fully share bird fluvirus samples with the World Health Organization until a newglobal mechanism is in place, a ...
submitted by kickingbird at Mar, 26, 2008 8:21 AM via(
http://news.yahoo.com/s/nm/20080324/hl_nm/birdflu_indonesia_dc

Don't just blame the chickens for flu (AP)
WASHINGTON - Intensive rice farming and large duck populations — not the number of chickens raised — may be the best predictors of where bird flu might ...
submitted by pub4world at Mar, 26, 2008 8:21 AM via(
http://news.yahoo.com/s/ap/20080324/ap_on_he_me/bird_flu_rice_fields

US officials launch bird flu stockpile in Thailand (AFP)
BANGKOK (AFP) - US officials on Tuesday officially opened a stockpile of equipment in Thailand designed to help Asian nations react rapidly to battle ...
submitted by wanglh at Mar, 26, 2008 8:21 AM via(
http://news.yahoo.com/s/afp/20080325/hl_afp/healthfluthailandus

--Flu In China & Flu Information Centre
Apr, 5, 2008 7:51 AM
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China rejects human-to-human bird flu report (AFP)
BEIJING (AFP) - China has rejected a study which found a probable case of human-to-human bird flu transmission in the country, state media reported. ...
submitted by kickingbird at Apr, 12, 2008 14:0 PM via(
http://news.yahoo.com/s/afp/20080412/wl_asia_afp/healthfluchina

Egyptian woman dies of bird flu (AFP)
CAIRO (AFP) - Egypt's health ministry announced the death on Friday of a woman from the H5N1 strain of bird flu, the 22nd human death from the disease ...
submitted by wanglh at Apr, 12, 2008 3:11 AM via(
http://news.yahoo.com/s/afp/20080411/wl_mideast_afp/healthfluegypt

(Yet) another human A/H5N1 influenza case and cluster – when should Europe be concerned?
A Chinese report of a case from Jiangsu province of an almost certain son-to-father transmission of avian influenza type A/H5N1 infection was ...
submitted by kickingbird at Apr, 11, 2008 12:47 PM via(
http://www.eurosurveillance.org/edition/v13n15/080410_5.asp

School closings may be no holiday for flu pandemic (Reuters)
CHICAGO (Reuters) - Closing schools during an influenzapandemic could prevent one in seven cases of flu, Britishresearchers said on Wednesday in a study ...
submitted by 2366 at Apr, 10, 2008 2:38 AM via(
http://news.yahoo.com/s/nm/20080409/hl_nm/birdflu_schools_dc

WHO: Avian influenza-situation in Egypt-update 8
8 April 2008 The Ministry of Health and Population of Egypt has announced a new human case of avian influenza A(H5N1) virus infection. The case is a ...
submitted by kickingbird at Apr, 9, 2008 7:0 AM via(
http://www.who.int/csr/don/2008_04_08/en/index.html

China confirms Tibetan bird flu outbreak
China's Ministry of Agriculture (MOA) on Monday confirmed an outbreak of bird flu at a farm in a Tibet Autonomous Region village. The ...
submitted by kickingbird at Apr, 8, 2008 12:53 PM via(
http://news.xinhuanet.com/english/2008-04/07/content_7935374.htm

Probable Case of Human-to-Human Bird Flu TransmissionReported (HealthDay)
MONDAY, April 7 (HealthDay News) -- Researchers have identified aprobable case of human-to-human transmission of bird flu in China. The finding lends ...
submitted by wanglh at Apr, 8, 2008 7:15 AM via(
link

Faster Test Detects Fake Tamiflu Drugs (HealthDay)
MONDAY, April 7 (HealthDay News) -- A fast method to detect fakeTamiflu, the mainstay medication for preventing and treating bird flu, hasbeen developed ...
submitted by 2366 at Apr, 8, 2008 7:15 AM via(
http://news.yahoo.com/s/hsn/20080407/hl_hsn/fastertestdetectsfaketamifludrugs

Human infects human with bird flu in China: study (AFP)
PARIS (AFP) - A 24-year old man in China probably infected his father with the H5N1 strain of bird flu before dying, renewing concerns that the disease ...
submitted by wanglh at Apr, 8, 2008 7:15 AM via(
http://news.yahoo.com/s/afp/20080407/hl_afp/healthfluchina

Chinese son likely gave bird flu to father: report (Reuters)
WASHINGTON (Reuters) - A 24-year-old Chinese man who diedof bird flu in December passed the virus directly to his fatherin a rare case of human-to-human ...
submitted by 2366 at Apr, 8, 2008 6:54 AM via(
http://news.yahoo.com/s/nm/20080407/hl_nm/birdflu_china_transmission_dc

Suspected bird flu outbreak in northeastern Indian state (AFP)
GUWAHATI, India (AFP) - Authorities were bracing to contain a suspected bird flu outbreak in another Indian state bordering Bangladesh, a senior official ...
submitted by wanglh at Apr, 7, 2008 14:37 PM via(
http://news.yahoo.com/s/afp/20080407/wl_sthasia_afp/healthfluindia

South Korea confirms new bird flu outbreak (Reuters)
SEOUL (Reuters) - South Korea on Monday confirmed a newoutbreak of bird flu at a duck farm in the southwest and saidit was investigating two other possible ...
submitted by kickingbird at Apr, 7, 2008 11:23 AM via(
http://news.yahoo.com/s/nm/20080407/sc_nm/birdflu_korea_dc

Egypt reports new bird flu death (AFP)
CAIRO (AFP) - An Egyptian teenager died from the H5N1 strain of bird flu on Saturday, the health ministry said, the 21st person to succumb to the virus ...
submitted by 2366 at Apr, 6, 2008 4:45 AM via(
http://news.yahoo.com/s/afp/20080405/wl_mideast_afp/healthfluegypt

South Korea reports new suspected bird flu case (Reuters)
SEOUL (Reuters) - South Korea on Saturday reported asuspected outbreak of the H5 strain of bird flu at a farm inthe southwest of the country, near another ...
submitted by 2366 at Apr, 5, 2008 11:49 AM via(
http://news.yahoo.com/s/nm/20080405/sc_nm/birdflu_korea_dc

WHO: Avian influenza-situation in Pakistan-update 2
3 April 2008 Two additional H5N1 cases were confirmed by serological testing, thus providing final H5N1 infection test results on a previously reported ...
submitted by kickingbird at Apr, 5, 2008 10:7 AM via(
http://www.who.int/csr/don/2008_04_03/en/index.html



Article


Source of High Pathogenicity of an Avian Influenza Virus H5N1:Why H5 is Better Cleaved by Furin
Origin of high pathogenicity of an emerging avian influenza H5N1 due to the -RRRKK- insertion at the cleavage loop of the hemagglutinin H5, was studied ...
submitted by kickingbird at Apr, 6, 2008 21:25 PM via(
link

Oseltamivir, an Anti-influenza Virus Drug, Produces Hypothermia in Mice
Oseltamivir phosphate (Tamiflu), an anti-influenza virus drug, is hydrolyzed by carboxylesterase to an active metabolite. The metabolite inhibits the influenza ...
submitted by kickingbird at Apr, 6, 2008 21:24 PM via(
link

Synthesis of full length PB1-F2 influenza A virus proteins from 'Spanish flu' and 'bird flu'
The proapoptotic influenza A virus PB1-F2 protein contributes to viral pathogenicity and is present in most human and avian isolates. Previous synthetic ...
submitted by kickingbird at Apr, 6, 2008 21:22 PM via(
link

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Apr, 12, 2008 19:27 PM
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65 million Indonesians at risk if bird flu mutates: official (AFP)
JAKARTA (AFP) - More than 60 million Indonesians could be infected with deadly bird flu if the virus mutates into a form transmissible between humans, ...
submitted by wanglh at Apr, 19, 2008 1:47 AM via(
http://news.yahoo.com/s/afp/20080418/hl_afp/healthfluindonesiadrillpandemic

New bird flu vaccine could last longer, protect more (AFP)
CHICAGO (AFP) - A new bird flu vaccine being developed by US researchers could provide broader protection, last longer and be easier to mass produce than ...
submitted by kickingbird at Apr, 18, 2008 9:56 AM via(
http://news.yahoo.com/s/afp/20080418/hl_afp/healthusfluvaccine

Experimental U.S. bird flu vaccine uses cold virus (Reuters)
WASHINGTON (Reuters) - An experimental bird flu vaccinethat uses a common cold virus and bits of DNA from the H5N1virus appears to stimulate an immune ...
submitted by kickingbird at Apr, 18, 2008 9:14 AM via(
http://news.yahoo.com/s/nm/20080418/hl_nm/birdflu_vaccine_dc

S.Korea culls 3 mln birds as bird flu spreads fast (Reuters)
SEOUL (Reuters) - South Korea said on Thursday it hadculled three million farmed birds and was probing seven freshcases of suspected bird flu, as the country ...
submitted by pub4world at Apr, 17, 2008 10:34 AM via(
http://news.yahoo.com/s/nm/20080417/wl_nm/birdflu_korea_dc

Egyptian 2-year-old boy infected with bird flu (Reuters)
CAIRO (Reuters) - A 2-year-old Egyptian boy has beeninfected with the deadly H5N1 bird flu virus, bringing thenumber of cases in the most populous Arab ...
submitted by kickingbird at Apr, 17, 2008 2:19 AM via(
http://news.yahoo.com/s/nm/20080416/hl_nm/birdflu_egypt_dc

SKorea upgrades bird flu alert, troops on standby (AFP)
SEOUL (AFP) - South Korea on Wednesday issued a nationwide bird flu alert, deployed troops and put firefighters on standby to try to contain the spread ...
submitted by pub4world at Apr, 16, 2008 21:22 PM via(
http://news.yahoo.com/s/afp/20080416/hl_afp/healthfluskorea

Japan to vaccinate medical workers against bird flu (AFP)
TOKYO (AFP) - Japan is to vaccinate thousands of medical workers and officials against bird flu to prepare for a possible pandemic, a health ministry official ...
submitted by kickingbird at Apr, 16, 2008 19:54 PM via(
http://news.yahoo.com/s/afp/20080416/hl_afp/healthflujapanvaccine

Small company gets U.S. go-ahead on bird flu patch (Reuters)
WASHINGTON (Reuters) - A small biotechnology company tryingto develop needle-free vaccines won a boost to its efforts onTuesday with U.S. government approval ...
submitted by 2366 at Apr, 16, 2008 6:16 AM via(
http://news.yahoo.com/s/nm/20080415/hl_nm/birdflu_patch_dc

Japan to vaccinate medical workers for bird flu (Reuters)
TOKYO (Reuters) - Japan plans to vaccinate 6,000 medicalworkers and quarantine officers with stockpiled bird fluvaccines to check their effectiveness and ...
submitted by 2366 at Apr, 15, 2008 17:47 PM via(
http://news.yahoo.com/s/nm/20080415/hl_nm/birdflu_japan_dc

South Korea probes new suspected bird flu cases (Reuters)
SEOUL (Reuters) - South Korea said on Tuesday it wasinvestigating four new suspected cases of bird flu, includingone near Seoul, adding to a string of ...
submitted by wanglh at Apr, 15, 2008 16:15 PM via(
http://news.yahoo.com/s/nm/20080415/hl_nm/birdflu_korea_dc

Indonesia, US must cooperate on bird flu: US official (AFP)
JAKARTA (AFP) - Indonesia and the United States must work together to prevent a global bird flu pandemic, the top US health official said here Monday. ...
submitted by kickingbird at Apr, 15, 2008 2:23 AM via(
http://news.yahoo.com/s/afp/20080414/hl_afp/healthfluindonesiaus

Bird flu case caused by deadly strain (AP)
SEOUL, South Korea - South Korea"e;s government confirmed a fourth outbreak of the H5N1 bird flu virus in the country"e;s southwest Sunday, as ...
submitted by kickingbird at Apr, 14, 2008 23:6 PM via(
http://news.yahoo.com/s/ap/20080413/ap_on_re_as/skorea_bird_flu

South Korea confirms latest deadly bird flu strain (Reuters)
SEOUL (Reuters) - South Korea on Sunday confirmed itslatest case of bird flu as from the deadly H5N1 strain, addingto a string of outbreaks in recent weeks ...
submitted by 2366 at Apr, 14, 2008 23:6 PM via(
http://news.yahoo.com/s/nm/20080413/hl_nm/birdflu_korea_dc

Indonesia says to launch bird flu pandemic plan (Reuters)
JAKARTA (Reuters) - Indonesia, which has the highest deathtoll from bird flu of any country, will launch a plan laterthis week to deal with a possible ...
submitted by pub4world at Apr, 14, 2008 23:6 PM via(
http://news.yahoo.com/s/nm/20080414/hl_nm/birdflu_indonesia_dc



Article


Activation of interleukin-32 pro-inflammatory pathway in response to influenza A virus infection
BACKGROUND: Interleukin (IL)-32 is a recently described pro-inflammatory cytokine that has been reported to be induced by bacteria treatment in culture ...
submitted by kickingbird at Apr, 18, 2008 23:41 PM via(
http://www.plosone.org/article/info:doi/10.1371/journal.pone.0001985

Comparative Efficacy of Neutralizing Antibodies Elicited by Recombinant Hemagglutinin Proteins from Avian H5N1 Influenza Virus
Although human transmission of avian H5N1 virus remains low, the prevalence of this highly pathogenic infection in avian species underscores the need for ...
submitted by kickingbird at Apr, 18, 2008 23:30 PM via(
link

Sulfatide Is Required for Efficient Replication of Influenza A Virus
Sulfatide is abundantly expressed in various mammalian organs, including the intestine and trachea, in which influenza A viruses (IAVs) replicate. However, ...
submitted by kickingbird at Apr, 18, 2008 23:28 PM via(
link

The genomic and epidemiological dynamics of human influenza A virus.
The evolutionary interaction between influenza A virus and the human immune system, manifest as 'antigenic drift' of the viral haemagglutinin, is one of ...
submitted by kickingbird at Apr, 18, 2008 23:24 PM via(
link

Multiple Sublineages of Influenza A Virus (H5N1), Vietnam, 2005-2007
Phylogenetic analysis of influenza subtype H5N1 viruses isolated from Vietnam during 2005-2007 shows that multiple sublineages are present in Vietnam. ...
submitted by kickingbird at Apr, 13, 2008 11:45 AM via(
link

Molecular analysis of the first avian influenza H5N1 isolates from fowl in Romania
Since the events of avian influenza (AI) caused by H5N1 subtype from Hong Kong (1997), the people worldwide have been confronted with new waves of epizootic ...
submitted by kickingbird at Apr, 13, 2008 11:42 AM via(
link

Modelling and prediction of weekly incidence of influenza A specimens in England and Wales
SUMMARYWe propose a rather simple model, which fits well the weekly human influenza incidence data from England and Wales. A standard way to analyse seasonally ...
submitted by kickingbird at Apr, 13, 2008 11:41 AM via(
link

Wild Ducks as Long-Distance Vectors of Highly Pathogenic Avian Influenza Virus (H5N1)
Wild birds have been implicated in the expansion of highly pathogenic avian influenza virus (H5N1) outbreaks across Asia, the Middle East, Europe, and ...
submitted by kickingbird at Apr, 13, 2008 11:41 AM via(
link

Reassortant Avian Influenza Virus (H5N1) in Poultry, Nigeria, 2007
Genetic characterization of a selection of influenza virus (H5N1) samples, circulating in 8 Nigerian states over a 39-day period in early 2007, indicates ...
submitted by kickingbird at Apr, 13, 2008 11:39 AM via(
link

Multi-antigen vaccines based on complex adenovirus vectors induce protective immune responses against H5N1 avian influenza viruses
There are legitimate concerns that the highly pathogenic H5N1 avian influenza virus could adapt for human-to-human transmission and cause a pandemic similar ...
submitted by kickingbird at Apr, 13, 2008 11:39 AM via(
link

Level of protection of chickens against highly pathogenic H5 avian influenza virus with Newcastle disease virus based live attenuated vector vaccine depends on homology of H5 sequence between vaccine
Vaccination of poultry against avian influenza is of high priority, in particular after the dramatic spread of subtype H5N1 in Asia, Africa and Europe. ...
submitted by kickingbird at Apr, 13, 2008 11:38 AM via(
link

Acute Childhood Encephalitis and Encephalopathy Associated With Influenza: A Prospective 11-Year Review
BACKGROUND:: Influenza virus infection has been associated with a variety of neurologic complications. The objective of this study was to evaluate prospectively ...
submitted by kickingbird at Apr, 13, 2008 11:38 AM via(
link

Proteomics analysis of differential expression of cellular proteins in response to avian H9N2 virus infection in human cells
We present the first proteomic analysis on the cellular responses to avian influenza virus (H9N2) infection in a human cell line in different time courses ...
submitted by kickingbird at Apr, 13, 2008 11:37 AM via(
link

Influenza-associated pneumonia in a Turkish area with endemic avian influenza.
BACKGROUND AND OBJECTIVE: The aim of the study was to describe the effects of influenza associated with community-acquired pneumonia (CAP) on the outcome ...
submitted by kickingbird at Apr, 13, 2008 11:35 AM via(
link

Probable limited person-to-person transmission of highly pathogenic avian influenza A (H5N1) virus in China
BACKGROUND: In December, 2007, a family cluster of two individuals infected with highly pathogenic avian influenza A (H5N1) virus was identified in Jiangsu ...
submitted by kickingbird at Apr, 13, 2008 11:34 AM via(
link

Fine-epitope mapping of an antibody that binds the ectodomain of influenza matrix protein 2
Our previous work found that the monoclonal antibody 8C6, which recognized the epitope EVETPIRN on influenza A virus M2 protein, conferred protection against ...
submitted by kickingbird at Apr, 13, 2008 11:34 AM via(
link

Estimating the impact of school closure on influenza transmission from Sentinel data
The threat posed by the highly pathogenic H5N1 influenza virus requires public health authorities to prepare for a human pandemic. Although pre-pandemic ...
submitted by kickingbird at Apr, 13, 2008 11:32 AM via(
link

Swine infection with H9N2 influenza viruses in China in 2004
In 2004, H9N2 influenza A viruses were isolated from pigs with respiratory syndrome in commercial swine farms in Henan province, China. Antigenic and genetic ...
submitted by kickingbird at Apr, 13, 2008 11:32 AM via(
link

Isolation and genetic characterization of avian origin H9N2 influenza viruses from pigs in China
As pigs are susceptible to infection with both avian and human influenza A viruses, they have been proposed to be an intermediate host for the adaptation ...
submitted by kickingbird at Apr, 13, 2008 11:31 AM via(
link

Identification of a human monoclonal Fab with neutralizing activity against H3N2 influenza A strain from a newly constructed human Fab library
A combinatorial Fab library was constructed in pComb3H phagemid vectors, using RNA from peripheral blood lymphocytes of a healthy volunteer who had recovered ...
submitted by kickingbird at Apr, 13, 2008 11:30 AM via(
link

Oseltamivir Enhances Hippocampal Network Synchronization
Oseltamivir, a widely used anti-influenza drug, inhibits virus neuraminidase. A mammalian homologue of this enzyme is expressed in the brain, yet the effect ...
submitted by kickingbird at Apr, 13, 2008 11:29 AM via(
link

Human-Like Receptor Specificity Does Not Affect the Neuraminidase-Inhibitor Susceptibility of H5N1 Influenza Viruses
If highly pathogenic H5N1 influenza viruses acquire affinity for human rather than avian respiratory epithelium, will their susceptibility to neuraminidase ...
submitted by kickingbird at Apr, 13, 2008 11:28 AM via(
http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1000043

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Apr, 19, 2008 2:28 AM
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News
Japan confirms H5N1 bird flu strain in swans (Reuters)
TOKYO (Reuters) - Japan on Tuesday confirmed four swansfound last week were infected with the H5N1 strain of bird flu. It was the first case of bird flu ...
submitted by pub4world at Apr, 29, 2008 17:4 PM via(
http://news.yahoo.com/s/nm/20080429/sc_nm/birdflu_japan_dc

Nepal on flu alert, tests poultry on India border (Reuters)
KATHMANDU (Reuters) - Nepal has issued a bird flu alert andis testing poultry along the border with India, where the virusrages despite the culling of ...
submitted by 2366 at Apr, 29, 2008 13:28 PM via(
http://news.yahoo.com/s/nm/20080429/sc_nm/birdflu_nepal_dc

Japan detects bird flu in four wild swans (Reuters)
TOKYO (Reuters) - Japan has detected a strain of bird fluin four wild swans after stepping up checks following majoroutbreaks of the disease in neighboring ...
submitted by kickingbird at Apr, 28, 2008 19:19 PM via(
http://news.yahoo.com/s/nm/20080428/sc_nm/birdflu_japan_dc

Indonesia runs massive bird flu drill (AFP)
TUKADDAYA, Indonesia (AFP) - Hundreds of Indonesian villagers and health workers took part in a massive drill here Friday to prepare for a potentially ...
submitted by pub4world at Apr, 25, 2008 17:10 PM via(
http://news.yahoo.com/s/afp/20080425/wl_asia_afp/healthfluindonesia

Indonesians hold major drill for bird flu pandemic (AP)
BALI, Indonesia - Indonesia launched a major bird flu drill Friday that will test the ability of the nation hardest hit by the virus to respond to a possible ...
submitted by wanglh at Apr, 25, 2008 14:14 PM via(
http://news.yahoo.com/s/ap/20080425/ap_on_re_as/indonesia_bird_flu

Indonesia defends its bird flu stance against US criticism (AP)
JAKARTA, Indonesia - Indonesia does not want money for its samples of a deadly bird flu virus, a health official said Wednesday after the U.S. criticized ...
submitted by 2366 at Apr, 24, 2008 16:10 PM via(
http://news.yahoo.com/s/ap/20080424/ap_on_re_as/indonesia_us_bird_flu

Indian state suffers second bird flu outbreak (AFP)
AGARTALA, India (AFP) - An Indian state reported new bird flu cases Tuesday, little more than a week after it finished culling thousands of chickens to ...
submitted by 2366 at Apr, 23, 2008 13:49 PM via(
http://news.yahoo.com/s/afp/20080423/wl_sthasia_afp/healthfluindia

Bird flu resurfaces in northeast India (Reuters)
GUWAHATI, India (Reuters) - Authorities in a remotenortheastern state of India prepared to cull thousands ofchickens after a fresh outbreak of bird flu ...
submitted by kickingbird at Apr, 22, 2008 17:3 PM via(
http://news.yahoo.com/s/nm/20080422/hl_nm/birdflu_india_dc

South Korea checks soldier for bird flu infection (Reuters)
SEOUL (Reuters) - South Korea is testing to see if one ofthe workers taking part in a mass cull of poultry infected withbird flu may have become infected ...
submitted by wanglh at Apr, 22, 2008 9:28 AM via(
http://news.yahoo.com/s/nm/20080422/hl_nm/birdflu_korea_dc

South Korea has new bird flu case (Reuters)
SEOUL (Reuters) - South Korea on Monday said it planned tocull a record 5.3 million birds as it announced its 17th caseof bird flu in three weeks, in what ...
submitted by 2366 at Apr, 21, 2008 12:7 PM via(
http://news.yahoo.com/s/nm/20080421/hl_nm/birdflu_korea_dc

Myanmar declares itself bird flu free (AFP)
YANGON (AFP) - Myanmar's military government on Sunday declared the country bird-flu free after three months without an outbreak of the deadly virus, ...
submitted by pub4world at Apr, 20, 2008 18:29 PM via(
http://news.yahoo.com/s/afp/20080420/wl_asia_afp/myanmarhealthflu

WHO: Avian influenza-situation in Egypt-update 10
17 April 2008 -- The Ministry of Health and Population of Egypt has announced a new human case of avian influenza A(H5N1) virus infection. The case is ...
submitted by kickingbird at Apr, 20, 2008 0:44 AM via(
http://www.who.int/csr/don/2008_04_17/en/index.html

South Korea confirms fresh bird flu case in poultry (Reuters)
SEOUL (Reuters) - South Korea's Farm Ministry reported onSaturday a new outbreak of bird flu at a chicken farm in thesouthwest, taking the total confirmed ...
submitted by pub4world at Apr, 19, 2008 17:23 PM via(
http://news.yahoo.com/s/nm/20080419/hl_nm/birdflu_korea_dc



Article


Transmission of Avian Influenza Virus (H3N2) to Dogs
In South Korea, where avian influenza virus subtypes H3N2, H5N1, H6N1, and H9N2 circulate or have been detected, 3 genetically similar canine influenza ...
submitted by kickingbird at Apr, 27, 2008 19:49 PM via(
http://www.cdc.gov/eid/content/14/5/741.htm?s_cid=eid741_e

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Apr, 29, 2008 20:59 PM
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Japan confirms another bird flu case in swan (AFP)
TOKYO (AFP) - A dead swan tested positive for bird flu in northern Japan on Monday, the environment ministry said, less than a week after officials announced ...
submitted by pub4world at May, 5, 2008 18:30 PM via(
http://news.yahoo.com/s/afp/20080505/wl_asia_afp/healthflujapan

Bird flu spreading in SKorea, officials say (AFP)
SEOUL (AFP) - Bird flu outbreaks have spread to six of South Korea's nine provinces despite a massive cull which saw the slaughter of more than five ...
submitted by pub4world at May, 4, 2008 3:33 AM via(
http://news.yahoo.com/s/afp/20080503/hl_afp/healthfluskorea

Thailand free of bird flu: ministry (AFP)
BANGKOK (AFP) - Thailand on Friday declared itself free of bird flu after no outbreaks of the deadly virus were reported over the past 90 days. The agriculture ...
submitted by 2366 at May, 3, 2008 0:9 AM via(
http://news.yahoo.com/s/afp/20080502/hl_afp/healthfluthailand

OIE: Highly pathogenic avian influenza, Japan
Information received on 29/04/2008 from Dr Toshiro Kawashima, Director, International Animal Health Affairs Office, Ministry of Agriculture, Forestry and ...
submitted by kickingbird at Apr, 30, 2008 6:8 AM via(
http://www.oie.int

OIE: Low pathogenic avian influenza (poultry), Denmark
Information received on 29/04/2008 from Mr Torben Grubbe, M. Sc., Animal Health Division, Ministry of Food, Agriculture and Fisheries Danish Veterinary ...
submitted by kickingbird at Apr, 30, 2008 6:6 AM via(
http://www.oie.int

Many Egyptians keep birds despite bird flu: poll (Reuters)
CAIRO (Reuters) - Over a quarter of Egyptians who are awareof the dangers of the H5N1 bird flu virus continue to raisebirds at home despite warnings that ...
submitted by 2366 at Apr, 29, 2008 22:36 PM via(
http://news.yahoo.com/s/nm/20080429/hl_nm/birdflu_egypt_dc

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May, 6, 2008 11:36 AM
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Indonesia to provide bird flu data online (AP)
JAKARTA, Indonesia - Indonesia"e;s health minister says she will give all genetic information about her country"e;s bird flu virus to a new global database. ...
submitted by wanglh at May, 15, 2008 13:37 PM via(
http://news.yahoo.com/s/ap/20080515/ap_on_he_me/bird_flu_new_database

Bird flu pandemic seen needing multiple drugs (Reuters)
LONDON (Reuters) - Governments need to stockpile differentsorts of flu drugs -- not just Roche's Tamiflu -- to counterthe danger of resistance in a ...
submitted by 2366 at May, 15, 2008 1:24 AM via(
http://news.yahoo.com/s/nm/20080514/sc_nm/birdflu_drugs_dc

SKorea steps up fight against worst bird flu outbreak (AFP)
SEOUL (AFP) - South Korea is to disinfect all poultry farms nationwide to combat its worst outbreak of bird flu, the agriculture ministry said Tuesday. ...
submitted by kickingbird at May, 13, 2008 12:29 PM via(
http://news.yahoo.com/s/afp/20080513/wl_asia_afp/healthfluskorea

All poultry in Seoul killed after bird flu outbreak (AP)
SEOUL, South Korea - South Korean officials said Monday they have killed all poultry in Seoul, the capital, to curb the spread of bird flu following a ...
submitted by 2366 at May, 12, 2008 17:15 PM via(
http://news.yahoo.com/s/ap/20080512/ap_on_he_me/skorea_bird_flu

S Korea culls 15,000 poultry to prevent spreading of bird flu
SEOUL, May 12 (Xinhua) -- South Korean quarantine officials announced Monday that they have slaughtered and buried around 15,000 ...
submitted by pub4world at May, 12, 2008 16:31 PM via(
http://news.xinhuanet.com/english/2008-05/12/content_8152211.htm

SKorea doubles Tamiflu stockpile over bird flu fears (AFP)
SEOUL (AFP) - South Korea will double its stockpiles of antiviral flu medicine Tamiflu as avian flu has spread through most the country, health officials ...
submitted by pub4world at May, 10, 2008 19:29 PM via(
http://news.yahoo.com/s/afp/20080510/hl_afp/healthfluskorea

South Korea to double Tamiflu stockpile (AP)
SEOUL, South Korea - South Korea says it will double its stockpile of the antiviral drug Tamiflu as bird flu spreads among poultry across the country. ...
submitted by pub4world at May, 10, 2008 18:46 PM via(
http://news.yahoo.com/s/ap/20080510/ap_on_re_as/skorea_bird_flu

New outbreak of bird flu hits India: minister (AFP)
KOLKATA (AFP) - Bird flu has spread to the hilly Darjeeling district of eastern India which has been hit by avian influenza several times already this ...
submitted by wanglh at May, 10, 2008 14:44 PM via(
http://news.yahoo.com/s/afp/20080510/wl_sthasia_afp/healthfluindia

Residents seek check-ups after Seoul's first bird flu case (AFP)
SEOUL (AFP) - The first bird flu outbreak in South Korea's capital Seoul was caused by the virulent H5N1 strain, the agriculture ministry said Wednesday, ...
submitted by wanglh at May, 7, 2008 15:30 PM via(
http://news.yahoo.com/s/afp/20080507/wl_asia_afp/healthfluskorea

Bird flu spreads to South Korean capital (AFP)
SEOUL (AFP) - Bird flu has spread to South Korea's capital Seoul despite a massive nationwide cull that saw the slaughter of six million ducks and ...
submitted by 2366 at May, 7, 2008 0:15 AM via(
http://news.yahoo.com/s/afp/20080506/wl_asia_afp/healthfluskorea

Risk of bird flu pandemic probably growing: experts (Reuters)
GENEVA (Reuters) - The risk of a human influenza pandemicremains real and is probably growing as the bird flu virusbecomes entrenched in poultry in more ...
submitted by 2366 at May, 6, 2008 21:43 PM via(
http://news.yahoo.com/s/nm/20080506/hl_nm/birdflu_who_dc

South Korea"e;s bird flu outbreak spreads to Seoul (Reuters)
SEOUL (Reuters) - South Korea's worst outbreak of bird fluhas spread to the capital with agriculture ministry officialssaying on Tuesday four dead ...
submitted by kickingbird at May, 6, 2008 14:24 PM via(
http://news.yahoo.com/s/nm/20080506/hl_nm/birdflu_korea_dc

Bird flu center opened to protect S Asia
PHNOM PENH, April 7 (Xinhua) -- The U.S. Agency for International Development (USAID) has opened a regional center in Thailand ...
submitted by pub4world at May, 6, 2008 13:35 PM via(
http://news.xinhuanet.com/english/2008-04/07/content_7935050.htm



Article


Oseltamivir Prophylactic Regimens Prevent H5N1 Influenza Morbidity and Mortality in a Ferret Model.
Background. Current oseltamivir prophylactic regimens may not be as effective against highly pathogenic H5N1 influenza viruses as they are against ...
submitted by kickingbird at May, 6, 2008 11:43 AM via(
http://www.ncbi.nlm.nih.gov/pubmed/18422444

Severe seasonal influenza in ferrets correlates with reduced interferon and increased IL-6 induction
Even though ferrets are one of the principal animal models for influenza pathogenesis, the lack of suitable immunological reagents has so far limited their ...
submitted by kickingbird at May, 6, 2008 11:42 AM via(
http://www.ncbi.nlm.nih.gov/pubmed/18420248

--Flu In China & Flu Information Centre
May, 15, 2008 16:14 PM
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China: Bird flu patient in Beijing dies, investigation ongoing
Beijing municipal health authorities confirmed Tuesday a 19-year-old woman was infected with bird flu and died in Beijing Monday. Huang ...
submitted by kickingbird at Jan, 6, 2009 22:0 PM via(http://news.xinhuanet.com/english/2009-01/06/content_10612862.htm)

China: Suspected bird flu patient in Beijing dies
A suspected bird flu patient in Beijing has died, local health bureau said Tuesday. The woman named Huang Yanqing died at 7:20 a.m. Monday. Her age is ...
submitted by kickingbird at Jan, 6, 2009 17:57 PM via(http://news.xinhuanet.com/english/2009-01/06/content_10612862.htm)

Vietnam confirms girl infected with bird flu
An eight-year-old Vietnamese girl from northern Thanh Hoa Province has been infected with bird flu and hospitalized, said an official with the National ...
submitted by kickingbird at Jan, 6, 2009 17:57 PM via(http://news.xinhuanet.com/english/2009-01/06/content_10613215.htm)

Bird flu triggers alert in Nepali border areas with India
KATHMANDU, Jan. 6 (Xinhua) -- Following the reported outbreak of Avian Influenza in bordering Indian state of West Bengal ...
submitted by wanglh at Jan, 6, 2009 16:52 PM via(http://news.xinhuanet.com/english/2009-01/06/content_10611678.htm)

Hong Kong baby living in China has mild bird flu
A 2-month-old Hong Kong-born infant who lives in China has contracted a mild strain of bird flu, a health official said Tuesday. The baby girl, ...
submitted by kickingbird at Dec, 31, 2008 11:0 AM via(http://www.iht.com/articles/ap/2008/12/30/asia/AS-Hong-Kong-Bird-Flu.php)

Article

Development of blocking ELISA for detection of antibodies against avian influenza virus of the H7 subtype
BACKGROUND AND PURPOSE: The conventional method used for subtyping of antibodies against avian influenza viruses is hemagglutination inhibition (HI) test. ...
submitted by kickingbird at Jan, 6, 2009 22:56 PM via(http://www.ncbi.nlm.nih.gov/pubmed/...nel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)

Using Influenza-Like Illness Data to Reconstruct an Influenza Outbreak
The objective of this study was to reconstruct the type A influenza epidemic that occurred in the Research Triangle Park (RTP) region of North Carolina ...
submitted by kickingbird at Jan, 6, 2009 22:56 PM via(http://www.ncbi.nlm.nih.gov/pubmed/...nel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)

HLA class I molecules consistently present internal influenza epitopes
Cytotoxic T lymphocytes (CTL) limit influenza virus replication and prevent morbidity and mortality upon recognition of HLA class I presented epitopes ...
submitted by kickingbird at Jan, 6, 2009 22:55 PM via(http://www.ncbi.nlm.nih.gov/pubmed/...nel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)

Systemic infection of avian influenza A virus H5N1 subtype in human
The viral dissemination in a patient with avian influenza A subtype H5N1 infection was retrospectively studied by the immunohistochemical localization ...
submitted by kickingbird at Jan, 6, 2009 22:54 PM via(http://www.ncbi.nlm.nih.gov/pubmed/...nel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)

Predicting the anticipated emotional and behavioral responses to an avian flu outbreak
BACKGROUND: The purpose of this study was to develop a model to predict the emotional and behavioral responses to an avian flu outbreak. METHODS: The participants ...
submitted by kickingbird at Jan, 6, 2009 22:54 PM via(http://www.ncbi.nlm.nih.gov/pubmed/...nel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)

Multiple components contribute to ability of saliva to inhibit influenza viruses
INTRODUCTION: Saliva is a potentially important barrier against respiratory viral infection but its mechanism of action is not well studied. METHODS: We ...
submitted by kickingbird at Jan, 6, 2009 22:53 PM via(http://www.ncbi.nlm.nih.gov/pubmed/...nel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)

Examples of probable host-pathogen co-adaptation/co-evolution in isolated farmed animal populations in the mountainous regions of North Vietnam
In Vietnam, for a number of specific geographical and historical reasons, the mountainous areas have preserved an exceptional diversity of wild and domestic ...
submitted by kickingbird at Jan, 6, 2009 22:52 PM via(http://www.ncbi.nlm.nih.gov/pubmed/...nel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)

Transmission of influenza virus in a mammalian host is increased by PB2 amino acids 627K or 627E/701N
Since 2003, more than 380 cases of H5N1 influenza virus infection of humans have been reported. Although the resultant disease in these cases was often ...
submitted by kickingbird at Jan, 6, 2009 22:51 PM via(http://www.ncbi.nlm.nih.gov/pubmed/...nel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)

Two amino acid residues in the matrix protein M1 contribute to the virulence difference of H5N1 avian influenza viruses in mice.
A/duck/Guangxi/53/2002 (DKGX/53) and A/duck/Fujian/01/2002 (DKFJ/01) are H5N1 avian influenza viruses that are lethal in chickens. In mice, however, DKFJ/01 ...
submitted by kickingbird at Jan, 6, 2009 22:50 PM via(http://www.ncbi.nlm.nih.gov/pubmed/...nel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)

Characterization of a Canadian mink H3N2 influenza A virus isolate genetically related to triple reassortant swine influenza virus
In 2007, a H3N2 influenza A virus was isolated from Canadian mink. It was found to be phylogenetically related to a triple reassortant influenza virus ...
submitted by kickingbird at Jan, 6, 2009 22:49 PM via(http://www.ncbi.nlm.nih.gov/pubmed/...nel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)

Changes in H5N1 influenza virus hemagglutinin receptor binding domain affect systemic spread
The HA of influenza virus is a receptor-binding and fusion protein that is required to initiate infection. The HA receptor-binding domain determines the ...
submitted by kickingbird at Jan, 6, 2009 22:49 PM via(http://www.ncbi.nlm.nih.gov/pubmed/...nel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)

Human infection with highly pathogenic avian influenza virus (H5N1) in northern Vietnam, 2004-2005
We performed a retrospective case-series study of patients with influenza A (H5N1) admitted to the National Institute of Infectious and Tropical Diseases ...
submitted by kickingbird at Jan, 6, 2009 22:48 PM via(http://www.ncbi.nlm.nih.gov/pubmed/...nel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)

Experimental infection of dogs with avian-origin canine influenza A virus (H3N2)
Susceptible dogs were brought into contact with dogs experimentally infected with an avian-origin influenza A virus (H3N2) that had been isolated from ...
submitted by kickingbird at Jan, 6, 2009 22:47 PM via(http://www.ncbi.nlm.nih.gov/pubmed/...nel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)

Personal protective equipment and risk for avian influenza (H7N3)
An outbreak of avian influenza (H7N3) among poultry resulted in laboratory-confirmed disease in 1 of 103 exposed persons. Incomplete use of personal protective ...
submitted by kickingbird at Jan, 6, 2009 22:47 PM via(http://www.ncbi.nlm.nih.gov/pubmed/...nel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)

--Flu In China & Flu Information Centre
Jan, 6, 2009 23:8 PM

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China confirms H5N1 bird flu outbreak in Xinjiang
BEIJING, July 2 (Xinhua) -- China's northwestern Xinjiang Uygur autonomous region has reported an outbreak of H5N1 in poultry, the Ministry of Agriculture ...
submitted by kickingbird at Jul, 2, 2012 22:10 PM via(http://news.xinhuanet.com/english/china/2012-07/02/c_131690453.htm)

Discovery of new gene sheds light on flu infections
Scientists have discovered a new gene in the influenza virus that helps the virus control the body’s response to infection. Although this control is exerted ...
submitted by kickingbird at Jul, 1, 2012 8:14 AM via(http://www.ed.ac.uk:80/news/all-news/flu-280612)

China: Scaly-breasted munia tests positive for H5N1 virus in HongKong
Preliminary testing on a dead scaly-breasted munia found in Yuen Long has returned a positive result for the H5N1 avian influenza ...
submitted by kickingbird at Jun, 25, 2012 21:17 PM via(http://www.info.gov.hk/gia/general/201206/20/P201206200415.htm)

Article

An Overlapping Protein-Coding Region in Influenza A Virus Segment 3 Modulates the Host Response
Influenza A virus (IAV) infection leads to variable and imperfectly understood pathogenicity. We report that segment 3 of the virus contains a second open ...
submitted by kickingbird at Jul, 1, 2012 8:16 AM via(http://www.sciencemag.org/content/early/2012/06/27/science.1222213.abstract)

--Flu In China & Flu Information Centre
Jul, 2, 2012 22:17 PM

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