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Fauci (NIAID) on MSNBC

HenryN

Retired
Anthony Fauci was just on MSNBC discussing H1N1. He was relatively upbeat and expects significant levels of vaccine by mid-October.
 
Re: Fauci (NIAID) on MSNBC

He also discourage porphylactic use of osetamivir (except for those with underlying conditions), and also discouraged swine flu parties, noting that a small but real number of patients get into trouble and die.

He also thought that the spread of the virus in the fall would convince people to take the vaccine. He acknowledged that the yeild was only at 50% of expectations, but projections on availability used the 50% of expected number.
 
Re: Fauci (NIAID) on MSNBC

Anthony Fauci was just on MSNBC discussing H1N1. He was relatively upbeat and expects significant levels of vaccine by mid-October.

How much time (days, weeks?) does it for a vaccine to provide sufficient immunity to the virus?
 
Re: Fauci (NIAID) on MSNBC

How much time (days, weeks?) does it for a vaccine to provide sufficient immunity to the virus?
Normally it takes a couple of weeks. However, since this is a swine target which has not been seen by most being vaccinated, a booster is recommended, which I believe is given three weeks later. However, it is unclear when vaccine for boosters will be available.
Thus, optimally, there would be full immunity 4-6 weeks after the first shot (but it remains unclear how optimal the situation will be). Some have projected large volumes of the first shot being available in January, and boosters not ready for months after that (as long as a year from now).
 
Re: Fauci (NIAID) on MSNBC

> U.S. health officials say swine flu could strike up to 40 percent of Americans over the
> next two years and as many as several hundred thousand could die if a vaccine campaign
> and other measures aren't successful.

> He (Fauci) also discourage porphylactic use of osetamivir

why ?

> , and also discouraged swine flu parties, noting that a small but real number
> of patients get into trouble and die.

ohh, real numbers. Even positive integers, presumably.
336 deaths reported in USA and more than a million infected.
CFR=0.03%
Expected/estimated are 120M infected and ~200000 dead (if the vaccine campaign and other measures
are not successful) CFR = 0.17% 5-6 times more.
Assume an infection now protects with 50% for 1 year, that's about the same expectation
value to die from swine flu parties as the expected/estimated protection that they provide.
But we still have the vaccine-chance which weights more on the non-party side.

Chances are almost balanced for and against the parties (IMO) so some city or region
might try it so we can compare later and give advice to other regions,states,countries

Well, New York City (Queens) is a natural example

> He also thought that the spread of the virus in the fall would convince people to take
> the vaccine.

when it already did spread, then it's too late for that wave ?

> He acknwledged that the yeild was only at 50% of expecttaions, but projections on
> availability used the 50% of expected number.

what are those projections
 
Re: Fauci (NIAID) on MSNBC

Normally it takes a couple of weeks. However, since this is a swine target which ahs not been seen by most being vaccinated, a booster is recommended, which I believe is give three weeks later. However, it is unclear when vaccine for boosters will be available.
Thus, optimally, there would be full immunity 4-6 weeks after the first shot (but it remains unclear how optimal the situation will be). Some have projected large volumes of the first shot being available in January, and boosters not ready for months after that (as long as a year from now).


So hypothetically if we see a 1918 redux, where the majority of deaths occured in October. Getting a shot in mid October and a booster a couple of weeks later might mean that if you get infected in November that you have a rather good chance of having an immune response?

Unfortunately, if we are following the 1918 redux, heading out to get a vaccine shot in mid October, may just put you at more risk of getting infected.
 
Re: Fauci (NIAID) on MSNBC

it had been recommended to split the available vaccine
and rather give many people a low dose than fewer people the full dose
 
Re: Fauci (NIAID) on MSNBC

> u.s. Health officials say swine flu could strike up to 40 percent of americans over the
> next two years and as many as several hundred thousand could die if a vaccine campaign
> and other measures aren't successful.

> he (fauci) also discourage porphylactic use of osetamivir

why ?
h274y
 
Re: Fauci (NIAID) on MSNBC

weren't you the one who said it didn't come from drug use ?


so for the individual it would still make sense but he doesn't recommend it
because others might suffer.
Like recommending not to burn oil,drive cars because it pollutes the environment.
Will people follow ?
 
Re: Fauci (NIAID) on MSNBC

weren't you the one who said it didn't come from drug use ?
Reality Check.
I said spread of H274Y in SEASONAL H1N1 didn't come from drug use (or traveling salesmen). I also said that the H274Y in seasonal flu would lead to H274Y in H1N1 swine flu via recombination (H274Y would be on a swine background because of recombination and hitchhiking). Others said H274Y would be acquired by reassortment with seasonal flu. I also said H274Y spread in swine H1N1 would be ACCELERATED by widespread Tamiflu use.

As predicted, there are ZERO examples of H274Y (or anything else) being acquired by reassortment with circulating seasonal flu. However, there have been FIVE examples of H274Y on a swine background. One (Hong Kong ex-San Francisco) was from a patient who was NOT taking Tamiflu. The other four (Denmark Japan twice, Canada) were in patients on PROPHYLACTIC tamiflu (selecting a pre-exsiting minor population with H274Y - no examples of N294S).

The data has been exactly as predicted and the risk/reward of prophylactic Tamiflu is very high.
 
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