tetano
Editor, Senior Moderator
Ned Tijdschr Geneeskd. 2010;154(19):A1634.
[Fatal pneumonitis due to oseltamivir-resistant new influenza A(H1N1) in the case of an intensive care patient.]
[Article in Dutch]
Aardema H, Tulleken JE, van den Biggelaar RJ, Wolters BA, de Jager CM, Boucher CA, Riezebos-Brilman A.
Universitair Medisch Centrum Groningen.
Abstract
A 58-year-old man was submitted to our intensive care ward with respiratory failure due to pneumonitis. He had previously been treated for non-Hodgkin lymphoma by autologous stem cell transplantation, as a result of which bone marrow function was reduced. Further analysis showed infection with new influenza A(H1N1); typing revealed an oseltamivir-resistant subpopulation (H275Y). The patient was treated with oseltamivir and intravenously with zanamivir, but died of respiratory disease progression. This is the first published case of oseltamivir-resistant new influenza A(H1N1) infection in the Netherlands.
PMID: 20482913 [PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/20482913
[Fatal pneumonitis due to oseltamivir-resistant new influenza A(H1N1) in the case of an intensive care patient.]
[Article in Dutch]
Aardema H, Tulleken JE, van den Biggelaar RJ, Wolters BA, de Jager CM, Boucher CA, Riezebos-Brilman A.
Universitair Medisch Centrum Groningen.
Abstract
A 58-year-old man was submitted to our intensive care ward with respiratory failure due to pneumonitis. He had previously been treated for non-Hodgkin lymphoma by autologous stem cell transplantation, as a result of which bone marrow function was reduced. Further analysis showed infection with new influenza A(H1N1); typing revealed an oseltamivir-resistant subpopulation (H275Y). The patient was treated with oseltamivir and intravenously with zanamivir, but died of respiratory disease progression. This is the first published case of oseltamivir-resistant new influenza A(H1N1) infection in the Netherlands.
PMID: 20482913 [PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/20482913