tetano
Editor, Senior Moderator
Sci Rep. 2018 Feb 9;8(1):2752. doi: 10.1038/s41598-018-21058-w.
[h=1]Far-UVC light: A new tool to control the spread of airborne-mediated microbial diseases.[/h] Welch D[SUP]1[/SUP], Buonanno M[SUP]2[/SUP], Grilj V[SUP]2[/SUP], Shuryak I[SUP]2[/SUP], Crickmore C[SUP]2[/SUP], Bigelow AW[SUP]2[/SUP], Randers-Pehrson G[SUP]2[/SUP], Johnson GW[SUP]2[/SUP], Brenner DJ[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Airborne-mediated microbial diseases such as influenza and tuberculosis represent major public health challenges. A direct approach to prevent airborne transmission is inactivation of airborne pathogens, and the airborne antimicrobial potential of UVC ultraviolet light has long been established; however, its widespread use in public settings is limited because conventional UVC light sources are both carcinogenic and cataractogenic. By contrast, we have previously shown that far-UVC light (207-222 nm) efficiently inactivates bacteria without harm to exposed mammalian skin. This is because, due to its strong absorbance in biological materials, far-UVC light cannot penetrate even the outer (non living) layers of human skin or eye; however, because bacteria and viruses are of micrometer or smaller dimensions, far-UVC can penetrate and inactivate them. We show for the first time that far-UVC efficiently inactivates airborne aerosolized viruses, with a very low dose of 2 mJ/cm[SUP]2[/SUP] of 222-nm light inactivating >95% of aerosolized H1N1 influenza virus. Continuous very low dose-rate far-UVC light in indoor public locations is a promising, safe and inexpensive tool to reduce the spread of airborne-mediated microbial diseases.
PMID: 29426899 DOI: 10.1038/s41598-018-21058-w
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[h=1]Far-UVC light: A new tool to control the spread of airborne-mediated microbial diseases.[/h] Welch D[SUP]1[/SUP], Buonanno M[SUP]2[/SUP], Grilj V[SUP]2[/SUP], Shuryak I[SUP]2[/SUP], Crickmore C[SUP]2[/SUP], Bigelow AW[SUP]2[/SUP], Randers-Pehrson G[SUP]2[/SUP], Johnson GW[SUP]2[/SUP], Brenner DJ[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Airborne-mediated microbial diseases such as influenza and tuberculosis represent major public health challenges. A direct approach to prevent airborne transmission is inactivation of airborne pathogens, and the airborne antimicrobial potential of UVC ultraviolet light has long been established; however, its widespread use in public settings is limited because conventional UVC light sources are both carcinogenic and cataractogenic. By contrast, we have previously shown that far-UVC light (207-222 nm) efficiently inactivates bacteria without harm to exposed mammalian skin. This is because, due to its strong absorbance in biological materials, far-UVC light cannot penetrate even the outer (non living) layers of human skin or eye; however, because bacteria and viruses are of micrometer or smaller dimensions, far-UVC can penetrate and inactivate them. We show for the first time that far-UVC efficiently inactivates airborne aerosolized viruses, with a very low dose of 2 mJ/cm[SUP]2[/SUP] of 222-nm light inactivating >95% of aerosolized H1N1 influenza virus. Continuous very low dose-rate far-UVC light in indoor public locations is a promising, safe and inexpensive tool to reduce the spread of airborne-mediated microbial diseases.
PMID: 29426899 DOI: 10.1038/s41598-018-21058-w
Free full text