tetano
Editor, Senior Moderator
J Clin Microbiol. 2014 Oct 22. pii: JCM.02322-14. [Epub ahead of print]
Family Clusters of Avian Influenza A H7N9 Infection in Guangdong Province, China.
Yi L1, Guan D2, Kang M2, Wu J2, Zeng X2, Lu J1, Rutherford S3, Zou L2, Liang L2, Ni H2, Zhang X2, Zhong H2, He J2, Lin J2, Ke C4.
Author information
Abstract
Since its first identification, the epizootic avian influenza A H7N9 has continued in China. Two waves were observed during this outbreak. No cases were reported from Guangdong province during the first wave but this province became one of the prime outbreak sites during the second wave. In order to identify the transmission potential of this continuously evolving infectious virus, our research group monitored all clusters of H7N9 infections during the second wave of the epidemic in Guangdong province. Epidemiologic, clinical, and virological data on these patients were collected and analyzed. Three family clusters including six cases of H7N9 infection were recorded. The virus caused severe disease in two adult patients but only mild symptoms for all the four pediatric patients. All cases reported direct poultry or poultry market exposure history. Relevant environment samples collected according to their reported exposures tested H7N9 positive. Virus isolates from patients in the same cluster shared high sequence similarities. In conclusion, although continually evolving the currently circulating H7N9 viruses in Guangdong province have not yet demonstrated the capacity for efficient and sustained person-to-person transmission.
Copyright ? 2014, American Society for Microbiology. All Rights Reserved.
PMID:
25339399
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/25339399
Family Clusters of Avian Influenza A H7N9 Infection in Guangdong Province, China.
Yi L1, Guan D2, Kang M2, Wu J2, Zeng X2, Lu J1, Rutherford S3, Zou L2, Liang L2, Ni H2, Zhang X2, Zhong H2, He J2, Lin J2, Ke C4.
Author information
Abstract
Since its first identification, the epizootic avian influenza A H7N9 has continued in China. Two waves were observed during this outbreak. No cases were reported from Guangdong province during the first wave but this province became one of the prime outbreak sites during the second wave. In order to identify the transmission potential of this continuously evolving infectious virus, our research group monitored all clusters of H7N9 infections during the second wave of the epidemic in Guangdong province. Epidemiologic, clinical, and virological data on these patients were collected and analyzed. Three family clusters including six cases of H7N9 infection were recorded. The virus caused severe disease in two adult patients but only mild symptoms for all the four pediatric patients. All cases reported direct poultry or poultry market exposure history. Relevant environment samples collected according to their reported exposures tested H7N9 positive. Virus isolates from patients in the same cluster shared high sequence similarities. In conclusion, although continually evolving the currently circulating H7N9 viruses in Guangdong province have not yet demonstrated the capacity for efficient and sustained person-to-person transmission.
Copyright ? 2014, American Society for Microbiology. All Rights Reserved.
PMID:
25339399
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/25339399