tetano
Editor, Senior Moderator
BMC Public Health. 2016 Sep 2;16:922. doi: 10.1186/s12889-016-3602-z.
[h=1]Factors associated with hospitalization for seasonal influenza in a Japanese nonelderly cohort.[/h] Ono S[SUP]1[/SUP], Ono Y[SUP]2[/SUP], Matsui H[SUP]3[/SUP], Yasunaga H[SUP]3[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] Nonelderly patients may require hospitalization if their symptoms of influenza are severe. However, little evidence is available about the risk factors for hospitalization for influenza.
[h=4]METHODS:[/h] We used a multicenter outpatient and inpatient database to obtain patients' characteristics and clinical procedures. We identified patients aged <65 years with a confirmed diagnosis of influenza between October 2013 and December 2014. We used a Cox regression model to identify the risk factors for hospitalization, using a comparison group of individuals with a confirmed diagnosis of influenza but who were not hospitalized.
[h=4]RESULTS:[/h] Of 88,054 patients diagnosed with influenza, 276 (0.3 %) patients were hospitalized. With reference to patients aged 18-64 years, the hazard ratio (95 % confidence interval) for hospitalization in patients aged <2, 2-4, and 5-17 years was 12.25 (8.37-17.93), 4.56 (3.10-6.72) and 1.45 (1.03-2.05), respectively. Anemia, chronic obstructive pulmonary disease, neurologic disease, and regular steroid use were significantly associated with hospitalization. Hazard ratios were adjusted for age, sex, comorbidities, respiratory co-infection, virus type, and influenza season.
[h=4]CONCLUSIONS:[/h] Our findings suggest that younger age and several comorbidities are associated with higher probability of hospitalization for influenza.
[h=4]KEYWORDS:[/h] Hospitalization; Nonelderly patient; Risk factor; Seasonal influenza
PMID: 27590634 PMCID: PMC5009717 DOI: 10.1186/s12889-016-3602-z
[PubMed - in process] Free PMC Article
[h=1]Factors associated with hospitalization for seasonal influenza in a Japanese nonelderly cohort.[/h] Ono S[SUP]1[/SUP], Ono Y[SUP]2[/SUP], Matsui H[SUP]3[/SUP], Yasunaga H[SUP]3[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] Nonelderly patients may require hospitalization if their symptoms of influenza are severe. However, little evidence is available about the risk factors for hospitalization for influenza.
[h=4]METHODS:[/h] We used a multicenter outpatient and inpatient database to obtain patients' characteristics and clinical procedures. We identified patients aged <65 years with a confirmed diagnosis of influenza between October 2013 and December 2014. We used a Cox regression model to identify the risk factors for hospitalization, using a comparison group of individuals with a confirmed diagnosis of influenza but who were not hospitalized.
[h=4]RESULTS:[/h] Of 88,054 patients diagnosed with influenza, 276 (0.3 %) patients were hospitalized. With reference to patients aged 18-64 years, the hazard ratio (95 % confidence interval) for hospitalization in patients aged <2, 2-4, and 5-17 years was 12.25 (8.37-17.93), 4.56 (3.10-6.72) and 1.45 (1.03-2.05), respectively. Anemia, chronic obstructive pulmonary disease, neurologic disease, and regular steroid use were significantly associated with hospitalization. Hazard ratios were adjusted for age, sex, comorbidities, respiratory co-infection, virus type, and influenza season.
[h=4]CONCLUSIONS:[/h] Our findings suggest that younger age and several comorbidities are associated with higher probability of hospitalization for influenza.
[h=4]KEYWORDS:[/h] Hospitalization; Nonelderly patient; Risk factor; Seasonal influenza
PMID: 27590634 PMCID: PMC5009717 DOI: 10.1186/s12889-016-3602-z
[PubMed - in process] Free PMC Article