tetano
Editor, Senior Moderator
Med Intensiva. 2012 Feb 14. [Epub ahead of print]
Extracorporeal lung support in patients with severe respiratory failure secondary to the 2010-2011 winter seasonal outbreak of influenza A (H1N1) in Spain.
[Article in English, Spanish]
Bonastre J, Suberviola B, Pozo JC, Guerrero JE, Torres A, Rodr?guez A, Mart?n-Loeches I; SEMICYUC-CIBERES-REIPI working group.
Source
Servicio Medicina Intensiva, Hospital Universitario y Polit?cnico La Fe, CIBER Enfermedades Respiratorias, Valencia, Espa?a.
Abstract
OBJECTIVE:
To describe the use of extracorporeal membrane oxygenation (ECMO) in refractory respiratory failure.
DESIGN:
A prospective, observational, multi-center study was carried out.
SETTING:
Intensive Care Units (ICU) in 148 Spanish hospitals.
PATIENTS:
Subjects admitted during epidemic weeks 50-52 of 2010 and weeks 1-4 of 2011, receiving respiratory support with ECMO.
MAIN VARIABLES OF INTEREST:
Clinical and blood gas features, complications and survival of patients with ECMO.
RESULTS:
Out of 300 ICU admitted patients, 239 (79.6%) were mechanically ventilated. ECMO was available in only 5 ICUs. Nine patients were treated with ECMO (3% of the total and 3.2% of the ventilated patients). In 77.7% of the cases some hypoxemia rescue technique was previously used. ECMO was initiated when ARDS proved refractory to standard treatment. ECMO therapy was started a median of 4.5 days after the onset of mechanical ventilation. The median duration of ECMO was 6 days. Veno-venous (VV) ECMO was the most frequent cannulation mode (88.9%). Four patients had complications associated with ECMO therapy. The median ICU and hospital stay was 17 and 29 days, respectively. In five patients (55.5%), ECMO assistance was satisfactory suspended. The ICU and hospital survival rate was 44.4%.
CONCLUSIONS:
The use of ECMO in refractory respiratory failure in patients with influenza A (H1N1) is rare in Spain. The hospital survival achieved with its use allows it to be regarded as a possible rescue technique in these patients.
Copyright © 2011 Elsevier Espa?a, S.L. y SEMICYUC. All rights reserved.
PMID:
22341559
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/22341559
Extracorporeal lung support in patients with severe respiratory failure secondary to the 2010-2011 winter seasonal outbreak of influenza A (H1N1) in Spain.
[Article in English, Spanish]
Bonastre J, Suberviola B, Pozo JC, Guerrero JE, Torres A, Rodr?guez A, Mart?n-Loeches I; SEMICYUC-CIBERES-REIPI working group.
Source
Servicio Medicina Intensiva, Hospital Universitario y Polit?cnico La Fe, CIBER Enfermedades Respiratorias, Valencia, Espa?a.
Abstract
OBJECTIVE:
To describe the use of extracorporeal membrane oxygenation (ECMO) in refractory respiratory failure.
DESIGN:
A prospective, observational, multi-center study was carried out.
SETTING:
Intensive Care Units (ICU) in 148 Spanish hospitals.
PATIENTS:
Subjects admitted during epidemic weeks 50-52 of 2010 and weeks 1-4 of 2011, receiving respiratory support with ECMO.
MAIN VARIABLES OF INTEREST:
Clinical and blood gas features, complications and survival of patients with ECMO.
RESULTS:
Out of 300 ICU admitted patients, 239 (79.6%) were mechanically ventilated. ECMO was available in only 5 ICUs. Nine patients were treated with ECMO (3% of the total and 3.2% of the ventilated patients). In 77.7% of the cases some hypoxemia rescue technique was previously used. ECMO was initiated when ARDS proved refractory to standard treatment. ECMO therapy was started a median of 4.5 days after the onset of mechanical ventilation. The median duration of ECMO was 6 days. Veno-venous (VV) ECMO was the most frequent cannulation mode (88.9%). Four patients had complications associated with ECMO therapy. The median ICU and hospital stay was 17 and 29 days, respectively. In five patients (55.5%), ECMO assistance was satisfactory suspended. The ICU and hospital survival rate was 44.4%.
CONCLUSIONS:
The use of ECMO in refractory respiratory failure in patients with influenza A (H1N1) is rare in Spain. The hospital survival achieved with its use allows it to be regarded as a possible rescue technique in these patients.
Copyright © 2011 Elsevier Espa?a, S.L. y SEMICYUC. All rights reserved.
PMID:
22341559
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/22341559