tetano
Editor, Senior Moderator
Expert Rev Vaccines
. 2024 Jan-Dec;23(1):8-15.
doi: 10.1080/14760584.2023.2291184. Epub 2023 Dec 11. Time lapses between distribution of influenza vaccines to health authorities and their administration by General Practitioners (GPs) to older adults: a retrospective study over five influenza seasons in Italy
Francesco Lapi[SUP] 1 [/SUP], Ettore Marconi[SUP] 1 [/SUP], Elettra Fallani[SUP] 2 3 [/SUP], Marco Salvatore[SUP] 2 3 [/SUP], Maura Cambiaggi[SUP] 2 [/SUP], Alessandro Rossi[SUP] 4 [/SUP], Claudio Cricelli[SUP] 4 [/SUP]
Affiliations
Background: Delays in influenza vaccine delivery and administration can hinder vaccine coverage and protection. This study examines the differentials in distributing and administering adjuvanted trivalent (aTIV) and quadrivalent influenza vaccines (aQIV) to older adults in Italy's primary care setting and its potential impact on hospitalization risk over 5 epidemic seasons.
Methods: Using a primary care database, individuals aged ≥ 65 years were selected. The proportion of vaccine distribution to regional authorities and subsequent administration by GPs was estimated using census data. Using quantile (median) regression, we examined the relationship between velocities of vaccine distribution and administration (doses/week) and the incidence of hospitalizations.
Results: Over the 5 influenza seasons, the velocity of distribution and administration of aTIV/aQIV ranged 341-833 and 152-270 median doses/week; no trend was yielded for the difference between these velocities (p = 0.189) or vaccine coverage (p = 0.142). An association was observed for each differential dose/week between distributed and administered vaccines and all-cause hospitalizations with a 10% increase in 2017-2018, 54% in 2018-2019, and 12% in 2020-2021 season.
Conclusions: These findings highlight the importance of minimizing the time lapse between vaccine distribution and administration to mitigate the impact of influenza and address factors that contribute to vaccination barriers.
Keywords: Influenza vaccine; administration; distribution; elderly; influenza hospitalizations; older adults; time lapse; velocity.
. 2024 Jan-Dec;23(1):8-15.
doi: 10.1080/14760584.2023.2291184. Epub 2023 Dec 11. Time lapses between distribution of influenza vaccines to health authorities and their administration by General Practitioners (GPs) to older adults: a retrospective study over five influenza seasons in Italy
Francesco Lapi[SUP] 1 [/SUP], Ettore Marconi[SUP] 1 [/SUP], Elettra Fallani[SUP] 2 3 [/SUP], Marco Salvatore[SUP] 2 3 [/SUP], Maura Cambiaggi[SUP] 2 [/SUP], Alessandro Rossi[SUP] 4 [/SUP], Claudio Cricelli[SUP] 4 [/SUP]
Affiliations
- PMID: 38078867
- DOI: 10.1080/14760584.2023.2291184
Background: Delays in influenza vaccine delivery and administration can hinder vaccine coverage and protection. This study examines the differentials in distributing and administering adjuvanted trivalent (aTIV) and quadrivalent influenza vaccines (aQIV) to older adults in Italy's primary care setting and its potential impact on hospitalization risk over 5 epidemic seasons.
Methods: Using a primary care database, individuals aged ≥ 65 years were selected. The proportion of vaccine distribution to regional authorities and subsequent administration by GPs was estimated using census data. Using quantile (median) regression, we examined the relationship between velocities of vaccine distribution and administration (doses/week) and the incidence of hospitalizations.
Results: Over the 5 influenza seasons, the velocity of distribution and administration of aTIV/aQIV ranged 341-833 and 152-270 median doses/week; no trend was yielded for the difference between these velocities (p = 0.189) or vaccine coverage (p = 0.142). An association was observed for each differential dose/week between distributed and administered vaccines and all-cause hospitalizations with a 10% increase in 2017-2018, 54% in 2018-2019, and 12% in 2020-2021 season.
Conclusions: These findings highlight the importance of minimizing the time lapse between vaccine distribution and administration to mitigate the impact of influenza and address factors that contribute to vaccination barriers.
Keywords: Influenza vaccine; administration; distribution; elderly; influenza hospitalizations; older adults; time lapse; velocity.