tetano
Editor, Senior Moderator
Expert Rev Cardiovasc Ther
. 2023 May 19.
doi: 10.1080/14779072.2023.2216456. Online ahead of print. Prevalence of arrhythmia in COVID-19 patients with mild/moderate and severe illness: a prospective cohort study
Praveen Gupta[SUP] 1 [/SUP], Sandeep Bansal[SUP] 1 [/SUP], Anunay Gupta[SUP] 1 [/SUP], Kapil Gupta[SUP] 2 [/SUP], Sumita Saluja[SUP] 3 [/SUP], Sudheesh Kumar Kattumannil[SUP] 4 [/SUP]
Affiliations
Objectives: The type of arrhythmias, and their prevalence in mild/moderate and severe COVID-19 patients admitted to the hospital are unknown from a prospective cohort study.
Methods: Continuous electrocardiograms along with multiple ECGs were done in 305 consecutive hospitalized COVID-19 patients with mild/moderate and severe illness for the diagnosis of arrhythmias.
Results: In this study, the incidence of arrhythmias was 6.8% (21/305) in the target population. The incidence of arrhythmias was 9.2% (17/185) in patients with severe COVID-19 illness and 3.3% (4/120) in patients with mild/moderate COVID-19 illness with no significant difference (p = 0.063). All the arrhythmias were new-onset arrhythmias in this study. 95% (20/21) of these arrhythmias were atrial arrhythmia with 71.42% (15/21) being atrial fibrillation and one episode of sustained polymorphic ventricular tachycardia. We did not observe any episode of high-grade atrioventricular block, sustained monomorphic ventricular arrhythmia, or torsades de pointes arrhythmias in this study. The patients with arrhythmias were significantly more commonly admitted in the intensive care unit (80.9% vs. 50.7%; p: 0.007), were on a ventilator (47.6% vs. 21.4%; p: 0.006), and with high in-hospital mortality (57.1% versus 21.1%; p: 0.0001) than patients without arrhythmias.
Conclusion: Atrial arrhythmias were the most frequent arrhythmias in hospital-admitted COVID-19 patients. Among atrial arrhythmias, atrial fibrillation was the most common arrhythmia.
Trial registration: The study is registered at Clinical Trial Registry India (CTRI) (CTRI/2021/01/030788). (https://www.ctri.nic.in/).
Keywords: Arrhythmias; Atrial arrhythmias; COVID-19; Electrocardiogram; N-terminal pro-brain natriuretic peptide; Severe acute respiratory syndrome-coronavirus-2; Troponin.
. 2023 May 19.
doi: 10.1080/14779072.2023.2216456. Online ahead of print. Prevalence of arrhythmia in COVID-19 patients with mild/moderate and severe illness: a prospective cohort study
Praveen Gupta[SUP] 1 [/SUP], Sandeep Bansal[SUP] 1 [/SUP], Anunay Gupta[SUP] 1 [/SUP], Kapil Gupta[SUP] 2 [/SUP], Sumita Saluja[SUP] 3 [/SUP], Sudheesh Kumar Kattumannil[SUP] 4 [/SUP]
Affiliations
- PMID: 37204921
- DOI: 10.1080/14779072.2023.2216456
Objectives: The type of arrhythmias, and their prevalence in mild/moderate and severe COVID-19 patients admitted to the hospital are unknown from a prospective cohort study.
Methods: Continuous electrocardiograms along with multiple ECGs were done in 305 consecutive hospitalized COVID-19 patients with mild/moderate and severe illness for the diagnosis of arrhythmias.
Results: In this study, the incidence of arrhythmias was 6.8% (21/305) in the target population. The incidence of arrhythmias was 9.2% (17/185) in patients with severe COVID-19 illness and 3.3% (4/120) in patients with mild/moderate COVID-19 illness with no significant difference (p = 0.063). All the arrhythmias were new-onset arrhythmias in this study. 95% (20/21) of these arrhythmias were atrial arrhythmia with 71.42% (15/21) being atrial fibrillation and one episode of sustained polymorphic ventricular tachycardia. We did not observe any episode of high-grade atrioventricular block, sustained monomorphic ventricular arrhythmia, or torsades de pointes arrhythmias in this study. The patients with arrhythmias were significantly more commonly admitted in the intensive care unit (80.9% vs. 50.7%; p: 0.007), were on a ventilator (47.6% vs. 21.4%; p: 0.006), and with high in-hospital mortality (57.1% versus 21.1%; p: 0.0001) than patients without arrhythmias.
Conclusion: Atrial arrhythmias were the most frequent arrhythmias in hospital-admitted COVID-19 patients. Among atrial arrhythmias, atrial fibrillation was the most common arrhythmia.
Trial registration: The study is registered at Clinical Trial Registry India (CTRI) (CTRI/2021/01/030788). (https://www.ctri.nic.in/).
Keywords: Arrhythmias; Atrial arrhythmias; COVID-19; Electrocardiogram; N-terminal pro-brain natriuretic peptide; Severe acute respiratory syndrome-coronavirus-2; Troponin.